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- Handal, M, et al.
(författare)
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Opioid maintenance treatment of pregnant women in the Scandinavian countries
- 2020
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Ingår i: Nordisk alkohol- & narkotikatidskrift : NAT. - : SAGE Publications. - 1458-6126. ; 37:3, s. 298-312
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Tidskriftsartikel (refereegranskat)abstract
- WHO guidelines emphasise the need for descriptions of clinical practice and observational studies on risk and benefits of pharmacotherapies in pregnancy. The aims of the present study were to: (1) Describe opioid maintenance treatment (OMT) in the Scandinavian countries in general, and specifically for pregnant women, (2) Describe a project which utilises a new approach using registry-linkage data to examine associations between prenatal exposure to OMT and child outcomes: a Scandinavian cohort study of pregnant women in OMT during pregnancy (ScopeOMT). Data: Guidelines describing the treatment of persons with opioid use disorders in general, and specifically for pregnant women. Scandinavian registry-linkage data from ScopeOMT. Results: Registry data show that approximately 800 pregnant women received OMT during pregnancy in the period of the ScopeOMT study. Similarities across the Scandinavian countries include access to free healthcare and treatment; multidisciplinary teams trained to support pregnant women in OMT; buprenorphine as the recommended drug when initiating therapy; and a holistic focus on the patients’ lives. An important difference is that Norwegian women who use illegal substances that may harm the foetus may be admitted – voluntarily, or against their will – for parts of, or the remainder of the pregnancy to inpatient treatment at specialised clinics. Conclusion: Many similarities in the treatment provided to opioid-dependent persons in the Scandinavian countries place this area in an excellent position to combine the efforts and carry out observational studies concerning the safety of OMT during pregnancy.
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- Naim, M.M., et al.
(författare)
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A net present value assessment of make-to-order and make-to-stock manufacturing systems
- 2007
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Ingår i: Omega. - : Elsevier BV. - 0305-0483 .- 1873-5274. ; 35:5, s. 524-532
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Tidskriftsartikel (refereegranskat)abstract
- This paper shows the impact of using the net present value (NPV) on parameter selection in the ordering policy of a production planning and control system. Using a well understood and documented model, the net present value is used as an objective function to determine the discounted future variance costs resulting from the model's dynamics. The NPV of the variance (NPVv) is defined and applied to the model under make-to-order and make-to-stock conditions. We show that the cost structure of the manufacturing system defines the NPVv and hence aids in identifying the most appropriate control strategy to apply. © 2005 Elsevier Ltd. All rights reserved.
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- SHELDON, RW, et al.
(författare)
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NANOPLANKTON AND PICOPLANKTON GROWTH AND PRODUCTION IN THE BAY OF VILLEFRANCHE-SUR-MER (NW MEDITERRANEAN)
- 1992
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Ingår i: Hydrobiologia. - 0018-8158 .- 1573-5117. ; 241:2, s. 91-106
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Tidskriftsartikel (refereegranskat)abstract
- Plankton production in the Bay of Villefranche was relatively constant during March and April 1986 but the particle size at which the production occurred was more variable. At the beginning of the study, production was dominated by the larger (ca. 6 mum) flagellates but towards the end it was more or less equally divided between the nano- and picoplankton. There were considerable differences in the estimates of population growth rates, depending on the methods used, but on average the population doubling times were close to 12 hours for autotrophs and 24 hours for heterotrophs. As autotrophs do not grow during the night, each population was therefore doubling once per day. It seemed that each of the nano- or picoplankton populations could adversely affect the growth of the others. This could be either by simple predation or by some form of inhibition. Although nutrient levels in the bay were uniformly low, the addition of nutrients did not always stimulate algal growth. The plankton populations seemed to be both in a state of equilibrium and intense ecological competition.
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