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1.
  • de Ruijter, Markus J. T., et al. (författare)
  • Pipeline for automated assessment of intra- and inter-individual locomotive behavior in Drosophila melanogaster
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • While human psychology is studied extensively, a knowledge gap between psychology and neural physiology remains. Personality traits may be present in non-primate animals and are thought to have an evolutionary origin. Drosophila melanogaster are a highly used model organism due to their ease of culturing and handling. However, they have been little used for studying personality. In this article we describe a novel methodology that aims to assess locomotive individuality in Drosophila, as a first step into assessing potential personality traits. A dual experimental setup was performed where flies (N=40) were recorded six times, for five minutes, with ten minute breaks in between. In the first experimental setup, flies were aspirated back into a familiar vial containing food during the breaks. In the second setup, flies were kept in the recording arena for the whole duration of the experiment. Tracking of the Drosophila was performed using existing tracking software SLEAP. The resulting tracking data was subsequently examined for locomotion behavior as well as examined for more detailed behavioral motifs using B-SOiD. Finally, we assessed intra- and inter-fly differences based on the locomotion behavior. This setup resulted in an efficient experimental and computational pipeline capable of collecting and processing large amounts of high quality behavioral data. We show that the intra-individual differences are smaller than the inter-individual differences. The unsupervised clustering of behavioral motifs resulted in unusable clusters as they contained either multiple types of behavior, or were specific to individual recordings. We believe this pipeline may be of great use for studying behavioral patterns in Drosophila melanogaster in a broad manner and that combined experimental methods may start to reveal potential personalities in these organisms.
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2.
  • Jolin, Shan Williams, et al. (författare)
  • Multipartite entanglement in a microwave frequency comb
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Significant progress has been made with multipartite entanglement of discrete qubits, but continuous variable systems may provide a more scalable path toward entanglement of large ensembles. We demonstrate multipartite entanglement in a microwave frequency comb generated by a Josephson parametric amplifier subject to a bichromatic pump. We find 64 correlated modes in the transmission line using a multifrequency digital signal processing platform. Full inseparability is verified in a subset of seven modes. Our method can be expanded to generate even more entangled modes in the near future. 
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  • Resultat 1-3 av 3

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