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Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States.

Wang, Li-San (author)
Naj, Adam C (author)
Graham, Robert R (author)
show more...
Crane, Paul K (author)
Kunkle, Brian W (author)
Cruchaga, Carlos (author)
Murcia, Josue D Gonzalez (author)
Cannon-Albright, Lisa (author)
Baldwin, Clinton T (author)
Zetterberg, Henrik, 1973 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Blennow, Kaj, 1958 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Kukull, Walter A (author)
Faber, Kelley M (author)
Schupf, Nicole (author)
Norton, Maria C (author)
Tschanz, Joann T (author)
Munger, Ronald G (author)
Corcoran, Christopher D (author)
Rogaeva, Ekaterina (author)
Lin, Chiao-Feng (author)
Dombroski, Beth A (author)
Cantwell, Laura B (author)
Partch, Amanda (author)
Valladares, Otto (author)
Hakonarson, Hakon (author)
St George-Hyslop, Peter (author)
Green, Robert C (author)
Goate, Alison M (author)
Foroud, Tatiana M (author)
Carney, Regina M (author)
Larson, Eric B (author)
Behrens, Timothy W (author)
Kauwe, John S K (author)
Haines, Jonathan L (author)
Farrer, Lindsay A (author)
Pericak-Vance, Margaret A (author)
Mayeux, Richard (author)
Schellenberg, Gerard D (author)
Albert, Marilyn S (author)
Albin, Roger L (author)
Apostolova, Liana G (author)
Arnold, Steven E (author)
Barber, Robert (author)
Barmada, M Michael (author)
Barnes, Lisa L (author)
Beach, Thomas G (author)
Becker, James T (author)
Beecham, Gary W (author)
Beekly, Duane (author)
Bennett, David A (author)
Bigio, Eileen H (author)
Bird, Thomas D (author)
Blacker, Deborah (author)
Boeve, Bradley F (author)
Bowen, James D (author)
Boxer, Adam (author)
Burke, James R (author)
Buxbaum, Joseph D (author)
Cairns, Nigel J (author)
Cao, Chuanhai (author)
Carlson, Chris S (author)
Carroll, Steven L (author)
Chui, Helena C (author)
Clark, David G (author)
Cribbs, David H (author)
Crocco, Elizabeth A (author)
DeCarli, Charles (author)
DeKosky, Steven T (author)
Demirci, F Yesim (author)
Dick, Malcolm (author)
Dickson, Dennis W (author)
Duara, Ranjan (author)
Ertekin-Taner, Nilufer (author)
Fallon, Kenneth B (author)
Farlow, Martin R (author)
Ferris, Steven (author)
Frosch, Matthew P (author)
Galasko, Douglas R (author)
Ganguli, Mary (author)
Gearing, Marla (author)
Geschwind, Daniel H (author)
Ghetti, Bernardino (author)
Gilbert, John R (author)
Glass, Jonathan D (author)
Graff-Radford, Neill R (author)
Growdon, John H (author)
Hamilton, Ronald L (author)
Hamilton-Nelson, Kara L (author)
Harrell, Lindy E (author)
Head, Elizabeth (author)
Honig, Lawrence S (author)
Hulette, Christine M (author)
Hyman, Bradley T (author)
Jarvik, Gail P (author)
Jicha, Gregory A (author)
Jin, Lee-Way (author)
Jun, Gyungah (author)
Kamboh, M Ilyas (author)
Karydas, Anna (author)
Kaye, Jeffrey A (author)
Kim, Ronald (author)
Koo, Edward H (author)
Kowall, Neil W (author)
Kramer, Joel H (author)
Kramer, Patricia (author)
LaFerla, Frank M (author)
Lah, James J (author)
Leverenz, James B (author)
Levey, Allan I (author)
Li, Ge (author)
Lieberman, Andrew P (author)
Lopez, Oscar L (author)
Lunetta, Kathryn L (author)
Lyketsos, Constantine G (author)
Mack, Wendy J (author)
Marson, Daniel C (author)
Martin, Eden R (author)
Martiniuk, Frank (author)
Mash, Deborah C (author)
Masliah, Eliezer (author)
McCormick, Wayne C (author)
McCurry, Susan M (author)
McDavid, Andrew N (author)
McKee, Ann C (author)
Mesulam, M Marsel (author)
Miller, Bruce L (author)
Miller, Carol A (author)
Miller, Joshua W (author)
Montine, Thomas J (author)
Morris, John C (author)
Murrell, Jill R (author)
Olichney, John M (author)
Parisi, Joseph E (author)
Perry, William (author)
Peskind, Elaine (author)
Petersen, Ronald C (author)
Pierce, Aimee (author)
Poon, Wayne W (author)
Potter, Huntington (author)
Quinn, Joseph F (author)
Raj, Ashok (author)
Raskind, Murray (author)
Reiman, Eric M (author)
Reisberg, Barry (author)
Reitz, Christiane (author)
Ringman, John M (author)
Roberson, Erik D (author)
Rosen, Howard J (author)
Rosenberg, Roger N (author)
Sano, Mary (author)
Saykin, Andrew J (author)
Schneider, Julie A (author)
Schneider, Lon S (author)
Seeley, William W (author)
Smith, Amanda G (author)
Sonnen, Joshua A (author)
Spina, Salvatore (author)
Stern, Robert A (author)
Tanzi, Rudolph E (author)
Thornton-Wells, Tricia A (author)
Trojanowski, John Q (author)
Troncoso, Juan C (author)
Tsuang, Debby W (author)
Van Deerlin, Vivianna M (author)
Van Eldik, Linda J (author)
Vardarajan, Badri N (author)
Vinters, Harry V (author)
Vonsattel, Jean Paul (author)
Weintraub, Sandra (author)
Welsh-Bohmer, Kathleen A (author)
Williamson, Jennifer (author)
Wishnek, Sarah (author)
Woltjer, Randall L (author)
Wright, Clinton B (author)
Younkin, Steven G (author)
Yu, Chang-En (author)
Yu, Lei (author)
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 (creator_code:org_t)
American Medical Association (AMA), 2015
2015
English.
In: JAMA neurology. - : American Medical Association (AMA). - 2168-6157 .- 2168-6149. ; 72:2
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Recently, a rare variant in the amyloid precursor protein gene (APP) was described in a population from Iceland. This variant, in which alanine is replaced by threonine at position 673 (A673T), appears to protect against late-onset Alzheimer disease (AD). We evaluated the frequency of this variant in AD cases and cognitively normal controls to determine whether this variant will significantly contribute to risk assessment in individuals in the United States.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor
Wang, Li-San
Naj, Adam C
Graham, Robert R
Crane, Paul K
Kunkle, Brian W
Cruchaga, Carlos
show more...
Murcia, Josue D ...
Cannon-Albright, ...
Baldwin, Clinton ...
Zetterberg, Henr ...
Blennow, Kaj, 19 ...
Kukull, Walter A
Faber, Kelley M
Schupf, Nicole
Norton, Maria C
Tschanz, Joann T
Munger, Ronald G
Corcoran, Christ ...
Rogaeva, Ekateri ...
Lin, Chiao-Feng
Dombroski, Beth ...
Cantwell, Laura ...
Partch, Amanda
Valladares, Otto
Hakonarson, Hako ...
St George-Hyslop ...
Green, Robert C
Goate, Alison M
Foroud, Tatiana ...
Carney, Regina M
Larson, Eric B
Behrens, Timothy ...
Kauwe, John S K
Haines, Jonathan ...
Farrer, Lindsay ...
Pericak-Vance, M ...
Mayeux, Richard
Schellenberg, Ge ...
Albert, Marilyn ...
Albin, Roger L
Apostolova, Lian ...
Arnold, Steven E
Barber, Robert
Barmada, M Micha ...
Barnes, Lisa L
Beach, Thomas G
Becker, James T
Beecham, Gary W
Beekly, Duane
Bennett, David A
Bigio, Eileen H
Bird, Thomas D
Blacker, Deborah
Boeve, Bradley F
Bowen, James D
Boxer, Adam
Burke, James R
Buxbaum, Joseph ...
Cairns, Nigel J
Cao, Chuanhai
Carlson, Chris S
Carroll, Steven ...
Chui, Helena C
Clark, David G
Cribbs, David H
Crocco, Elizabet ...
DeCarli, Charles
DeKosky, Steven ...
Demirci, F Yesim
Dick, Malcolm
Dickson, Dennis ...
Duara, Ranjan
Ertekin-Taner, N ...
Fallon, Kenneth ...
Farlow, Martin R
Ferris, Steven
Frosch, Matthew ...
Galasko, Douglas ...
Ganguli, Mary
Gearing, Marla
Geschwind, Danie ...
Ghetti, Bernardi ...
Gilbert, John R
Glass, Jonathan ...
Graff-Radford, N ...
Growdon, John H
Hamilton, Ronald ...
Hamilton-Nelson, ...
Harrell, Lindy E
Head, Elizabeth
Honig, Lawrence ...
Hulette, Christi ...
Hyman, Bradley T
Jarvik, Gail P
Jicha, Gregory A
Jin, Lee-Way
Jun, Gyungah
Kamboh, M Ilyas
Karydas, Anna
Kaye, Jeffrey A
Kim, Ronald
Koo, Edward H
Kowall, Neil W
Kramer, Joel H
Kramer, Patricia
LaFerla, Frank M
Lah, James J
Leverenz, James ...
Levey, Allan I
Li, Ge
Lieberman, Andre ...
Lopez, Oscar L
Lunetta, Kathryn ...
Lyketsos, Consta ...
Mack, Wendy J
Marson, Daniel C
Martin, Eden R
Martiniuk, Frank
Mash, Deborah C
Masliah, Eliezer
McCormick, Wayne ...
McCurry, Susan M
McDavid, Andrew ...
McKee, Ann C
Mesulam, M Marse ...
Miller, Bruce L
Miller, Carol A
Miller, Joshua W
Montine, Thomas ...
Morris, John C
Murrell, Jill R
Olichney, John M
Parisi, Joseph E
Perry, William
Peskind, Elaine
Petersen, Ronald ...
Pierce, Aimee
Poon, Wayne W
Potter, Huntingt ...
Quinn, Joseph F
Raj, Ashok
Raskind, Murray
Reiman, Eric M
Reisberg, Barry
Reitz, Christian ...
Ringman, John M
Roberson, Erik D
Rosen, Howard J
Rosenberg, Roger ...
Sano, Mary
Saykin, Andrew J
Schneider, Julie ...
Schneider, Lon S
Seeley, William ...
Smith, Amanda G
Sonnen, Joshua A
Spina, Salvatore
Stern, Robert A
Tanzi, Rudolph E
Thornton-Wells, ...
Trojanowski, Joh ...
Troncoso, Juan C
Tsuang, Debby W
Van Deerlin, Viv ...
Van Eldik, Linda ...
Vardarajan, Badr ...
Vinters, Harry V
Vonsattel, Jean ...
Weintraub, Sandr ...
Welsh-Bohmer, Ka ...
Williamson, Jenn ...
Wishnek, Sarah
Woltjer, Randall ...
Wright, Clinton ...
Younkin, Steven ...
Yu, Chang-En
Yu, Lei
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About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Neurosciences
Articles in the publication
JAMA neurology
By the university
University of Gothenburg

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