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Sökning: WFRF:(Wisén Anita) > Medicin och hälsovetenskap

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2.
  • Hagströmer, Maria, et al. (författare)
  • Bedöma och utvärdera fysisk aktivitet
  • 2017. - 3
  • Ingår i: FYSS 2017 : Fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling - Fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling. - 9789198171129 ; , s. 250-266
  • Bokkapitel (refereegranskat)
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3.
  • Wisén, Anita, et al. (författare)
  • Exercise testing using a cycle or treadmill: a review of various protocols.
  • 1999
  • Ingår i: Physical Therapy Reviews. - 1743-288X. ; 4, s. 7-20
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract: In order to evaluate physical capacity it is neccesary to choose an appropriate method depending on the condition of the subject being tested and on the purpose of testing. A review has been carried out in order to present some of the protocols for evaluating exercise capacity which are in practical use. Twenty different test protocols for evaluating exercise capacity; 12 cycle protocols, six treadmill protocols and two protocols including both cycle and treadmill, are described in detail, as well as some of the physiological background of the tests. When testing subjects with reduced physical capacity, a protocol starting with a low work load and small increments is preferred. The test results can be reported as achieved oxygen uptake (V˙O2), metabolic equivalents (METs)or achieved work load (W). When testing healthy subjects and athletes, submaximal tests which estimate maximal oxygen uptake (V˙O2max) may be used. If high accuracy is required direct measurements of V˙O2 or V˙O2max are most reliable, regardless of which protocol is used.
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4.
  • Wisén, Anita, et al. (författare)
  • A comparison between two exercise tests on cycle; a computerised test versus the Åstand test.
  • 1995
  • Ingår i: Clin Physiol. ; 15:1, s. 91-102
  • Tidskriftsartikel (refereegranskat)abstract
    • Two submaximal cycle ergometer test methods, the Astrand nomogram test and a computerized two-point extrapolation test (Cat Eye ergociser, commercially available), were compared in order to determine agreement and repeatability of estimates of maximum oxygen consumption (VO2max). Twenty healthy women, divided into two groups of ten according to their age (mean 35.3 and mean 46.9), performed test-retest with each method. In both methods the VO2max was estimated from workload and the corresponding heart rate. The correlation between the VO2max using the two methods was high (r = 0.85, P < 0.001). Some of the estimates derived from the computerized test had large errors, which reduced the agreement between the tests. The variation (2SD), expressed in per cent of mean VO2max was 19% for the Astrand test and 34% for the computerized test. Furthermore, the computerized test underestimated the VO2max with approximately 5 ml kg-1 min-1 compared with the Astrand test. Due to this underestimation and the greater variation of the VO2max in the computerized test, it is not recommended to use the two methods interchangeably in clinical practice.
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5.
  • Garland, Stephen, et al. (författare)
  • Is Ross treadmill method an alternative to Åstrand cycle ergometer method?
  • 2017
  • Ingår i: European Journal of Physiotherapy. - : Informa UK Limited. - 2167-9169 .- 2167-9177. ; 19:3, s. 167-172
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: To assess the agreement between the Ross treadmill method and the Åstrand ergometer cycle method, and the repeatability of each method. Methodology: Twenty healthy people aged 22.5 ± 2.2 years were tested on two different days, each day with both methods with a pause of 30 min between the tests. The tests were executed in the reverse order the following test day. Major findings: There was no statistical difference between the methods. The correlation (R) between the methods was 0.85. The mean difference (95% CI) of the methods was 0.050 (0.046–0.054) L/min and the limit of the agreement (mean difference ±2SD) was 0.81 L/min. No significant differences in test-retest were shown for either test. The mean difference for Åstrand tests was 0.12 L/min and 0.08 L/min for the Ross tests. The coefficient of repeatability was 0.88 L/min (23%) for the Åstrand test, and 0.78 L/min (20%) for the Ross test. Conclusion: The Ross treadmill test could be used as an alternative to the Åstrand cycle ergometer test, showing good agreement and repeatability. The large variation should be considered when estimating aerobic capacity on an individual level, although either method could be used for group studies where maximal measurements are not possible.
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6.
  • Gustafsson, Anna, et al. (författare)
  • Effects of Acute Exercise on Circulating Soluble Form of the Urokinase Receptor in Patients With Major Depressive Disorder
  • 2017
  • Ingår i: Biomarker Insights. - : Sage Publications. - 1177-2719. ; 12, s. 1-6
  • Tidskriftsartikel (refereegranskat)abstract
    • Inflammation has been proposed to play a role in the generation of depressive symptoms. Previously, we demonstrated that patients with major depressive disorder (MDD) have increased plasma levels of the soluble form of the urokinase receptor (suPAR), a marker for low-grade inflammation. The aim of this study was to test the hypothesis that acute exercise would induce inflammatory response characterized by increased suPAR and elucidate whether patients with MDD display altered levels of suPAR in response to acute exercise. A total of 17 patients with MDD and 17 controls were subjected to an exercise challenge. Plasma suPAR (P-suPAR) was analyzed before, during, and after exercise. There was a significantly higher baseline P-suPAR in the patients with MDD, and the dynamic changes of P-suPAR during the exercise were significantly lower in the patients with MDD, compared with the controls. This study supports the hypothesis that an activation of systemic inflammatory processes, measured as elevated P-suPAR, is involved in the pathophysiology of depression. The study concludes that P-suPAR is influenced by acute exercise, most likely due to release from activated neutrophils.
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7.
  • Svensson, Philippa, et al. (författare)
  • The Borg scale is a sustainable method for prescribing and monitoring self-administered aerobic endurance exercise in patients with chronic kidney disease
  • 2023
  • Ingår i: European Journal of Physiotherapy. - : Informa UK Limited. - 2167-9169 .- 2167-9177. ; 25:5, s. 265-273
  • Tidskriftsartikel (refereegranskat)abstract
    • Aim: To examine adherence, performance, and safety of self-administered aerobic endurance exercise when exercise intensity was prescribed and self-monitored with the Borg RPE scale in patients with chronic kidney disease (CKD), and the relationship between performed exercise and change in walking distance. Materials and Methods: 97 men and 50 women (age 66 ± 14 years, measured GFR 22 ± 8 mL/min/1.73m2) were prescribed 60 min aerobic endurance exercise/week at RPE 13–15. The 6-minute walk test was measured at 0, 4, 8 and 12 months of exercise. Results: 100 patients completed the study, 80% reported exercise intensity at 12 months, 74% performed exercise within the prescribed RPE. Median RPE was 13 (13–15). Median duration was 56 (33–109) minutes/week. Patients with a short walking distance at baseline performed significantly less minutes of exercise/week (p = 0.039). There was no correlation between weekly duration and change in walking distance. No exercise-related incidents were recorded. Walking distance improved significantly by 30 ± 56 metres (p < 0.001). Conclusions: The Borg RPE scale is useful, acceptable, simple and safe for prescribing and monitoring intensity of self-administered aerobic endurance exercise in patients with CKD. A RPE of 13–15 improved walking distance in well-functioning and deconditioned patients, within a wide range of weekly duration of exercise.
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8.
  • Wisén, Anita, et al. (författare)
  • Plasma ANP and BNP during exercise in patients with major depressive disorder and in healthy controls
  • 2011
  • Ingår i: JOURNAL OF AFFECTIVE DISORDERS. - : Elsevier BV. - 0165-0327 .- 1573-2517. ; 129:1-3, s. 371-375
  • Tidskriftsartikel (refereegranskat)abstract
    • Increased levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been shown to reduce the hormones in the HPA axis. In this study we addressed the question whether patients with unmedicated major depressive disorder (MDD) might have altered baseline levels of these natriuretic peptides and an altered response to acute exercise. METHODS: An incremental exercise test was performed in 18 patients with MDD and in 18 healthy controls. Plasma concentrations of ANP and BNP were determined at rest, during the exercise test and 30 min post exercise using immunoradiometric assays. RESULTS: During the exercise test the concentrations of ANP and BNP increased significantly in both groups. The MDD group showed significantly lower levels of ANP than the controls at rest, at maximal work rate and post exercise and of BNP at rest and at maximal work rate. The dynamic changes of both ANP and BNP, respectively, from baseline to maximal work rate were significantly lower in the MDD group. A slightly lower (non-significant) maximal work rate was observed in the MDD group compared with the controls. LIMITATIONS: Group sizes are relatively limited. CONCLUSION: Lower concentrations of ANP and BNP during rest and exercise were observed in the MDD patients together with a decreased dynamic response to maximal exercise. Hypothetically, the reduced ANP and BNP concentration contributes to the high hormone levels in the HPA system seen in depressive disorders. Of interest for future research is whether physical training might increase the levels of ANP and BNP and thereby diminish depressive symptoms.
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