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- Bischof, P., et al.
(författare)
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Implantation of the human embryo: Research lines and models
- 2006
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Ingår i: Gynecologic and Obstetric Investigation. - : S. Karger AG. - 1423-002X .- 0378-7346. ; 62:4, s. 206-216
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Forskningsöversikt (refereegranskat)abstract
- Infertility is an increasing problem all over the world, and it has been estimated that 10 - 15% of couples in fertile age have fertility problems. Likewise induced unsafe abortion is a serious threat to women's health. Despite advances made in assisted reproduction techniques, little progress has been made in increasing the success rate during fertility treatment. This document describes a wide range of projects carried out to increase the understanding in the field of embryo implantation research. The 'Fruitful' research network was created to encourage collaborations within the consortium and to describe our different research potentials to granting agencies or private sponsors. Copyright (c) 2006 S. Karger AG, Basel.
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| 2. |
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| 3. |
- Dawes, C., et al.
(författare)
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The functions of human saliva: A review sponsored by the World Workshop on Oral Medicine VI
- 2015
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Ingår i: Archives of Oral Biology. - : Elsevier BV. - 0003-9969. ; 60:6, s. 863-874
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Forskningsöversikt (refereegranskat)abstract
- This narrative review of the functions of saliva was conducted in the PubMed, Embase and Web of Science databases. Additional references relevant to the topic were used, as our key words did not generate references which covered all known functions of saliva. These functions include maintaining a moist oral mucosa which is less susceptible to abrasion, and removal of micro-organisms, desquamated epithelial cells, leucocytes and food debris by swallowing. The mucins form a slimy coating on all surfaces in the mouth and act as a lubricant during such processes as mastication, formation of a food bolus, swallowing and speaking. Saliva provides the fluid in which solid tastants may dissolve and distributes tastants around the mouth to the locations of the taste buds. The hypotonic unstimulated saliva facilitates taste recognition. Salivary amylase is involved in digestion of starches. Saliva acts as a buffer to protect oral, pharyngeal and oesophageal mucosae from orally ingested acid or acid regurgitated from the stomach. Saliva protects the teeth against acid by contributing to the acquired enamel pellicle, which forms a renewable lubricant between opposing tooth surfaces, by being supersaturated with respect to tooth mineral, by containing bicarbonate as a buffer and urea and by facilitating clearance of acidic materials from the mouth. Saliva contains many antibacterial, antiviral and antifungal agents which modulate the oral microbial flora in different ways. Saliva also facilitates the healing of oral wounds. Clearly, saliva has many functions which are needed for proper protection and functioning of the human body. (C) 2015 Elsevier Ltd. All rights reserved. RAMS CK, 1988, GASTROENTEROLOGY, V95, P1460
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| 4. |
- Karlsson, Maths, 1978, et al.
(författare)
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Neutron Reflectivity in Corrosion Research on Metals
- 2024
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Ingår i: ACS Materials Au. - 2694-2461. ; 4:4, s. 346-353
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Forskningsöversikt (refereegranskat)abstract
- Neutron reflectivity (NR) is potentially a powerful tool for characterizing chemical and morphological changes in thin films and at buried interfaces in corrosion science. While the scope of NR is limited by its inherent demands for low surface roughness and high sample planarity, these drawbacks are compensated for by the unique ability to detect light elements and distinguish between isotopes. Furthermore, the generally weak absorption of neutrons by matter allows the use of bulky sample environments and in situ experiments. In particular, the layer thickness range of 3-100 nm accessible by NR is appropriate for studying air-formed films and passive films, which are crucial for the ability of metallic materials to resist corrosion, as well as for investigating the interaction of metal surfaces with hydrogen and its compounds, e.g., water. Also, NR is suitable for studying early stages of oxide growth on metals at high temperature, including the transition from Cabrera-Mott-type films to Wagner-type growth. Here, we outline key characteristics of NR as applied to the study of corrosion of metals, exemplified by earlier work, and discuss perspectives for future work in the field. The aim of our work is to stimulate the application of the unique capabilities of NR to corrosion science.
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| 6. |
- Wolff, Aviva L., et al.
(författare)
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Dynamic assessment of the upper extremity: a review of available and emerging technologies
- 2023
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Ingår i: Journal of Hand Surgery, European Volume. - : SAGE PUBLICATIONS LTD. - 1753-1934 .- 2043-6289. ; 48:5, s. 404-411
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Forskningsöversikt (refereegranskat)abstract
- The purpose of this review article is to provide an update on the realm of emerging technology available for the assessment of dynamic functional movement of the hand and upper limb. A critical overview of the literature and a conceptual framework for use of such technologies is proposed. The framework explores three broad purpose categories including customization of care, functional surveillance and interventions through biofeedback strategies. State-of-the-art technologies are described, from basic activity monitors to feedback-enabled robotic gloves, along with exemplar trials and clinical applications. The future of technologies innovation in hand pathology is proposed in the context of the current obstacles and opportunities for hand surgeons and therapists.
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| 7. |
- Wolff, Johannes M., et al.
(författare)
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Is intermittent androgen-deprivation therapy beneficial for patients with advanced prostate cancer?
- 2014
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Ingår i: BJU International. - : Wiley. - 1464-4096. ; 114:4, s. 476-483
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Forskningsöversikt (refereegranskat)abstract
- Use of intermittent androgen-deprivation therapy (IADT) in patients with prostate cancer has been evaluated in several studies, in an attempt to delay the development of castration resistance and reduce side-effects associated with ADT. However it is still not clear whether survival is adversely affected in patients treated with IADT. In this review, we explore the available data in an attempt to identify the most suitable candidate patients for IADT, and discuss factors that may inform appropriate patient stratification. ADT is first-line treatment for advanced/metastatic prostate cancer and is also recommended for use with definitive radiotherapy for high-risk localised prostate cancer. The changes in hormone levels induced by ADT can lead to short-and long-term side-effects which, although treatable in most cases, can significantly reduce the tolerability of ADT treatment. IADT has been investigated in several phase II and phase III studies in patients with locally advanced or metastatic prostate cancer, in an attempt to delay time to tumour progression and reduce the side-effect burden of ADT. In selected patient groups IADT is no less effective than continuous ADT, ameliorating the impact of ADT-related side-effects, and, to a degree, their impact on patient health-related quality of life (HRQL). Further comparative study is required, particularly in relation to HRQL and long-term complications associated with ADT.
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