SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Wu MJ) "

Sökning: WFRF:(Wu MJ)

Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  • Tidskriftsartikel (refereegranskat)
  •  
3.
  • Forskningsöversikt (refereegranskat)
  •  
4.
  • Campbell, PJ, et al. (författare)
  • Pan-cancer analysis of whole genomes
  • 2020
  • Ingår i: Nature. - : Nature Publishing Group. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82-
  • Tidskriftsartikel (refereegranskat)
  •  
5.
  • Tidskriftsartikel (refereegranskat)
  •  
6.
  • Tidskriftsartikel (refereegranskat)
  •  
7.
  • Michailidou, Kyriaki, et al. (författare)
  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
  • 2015
  • Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 47:4, s. 373-U127
  • Tidskriftsartikel (refereegranskat)abstract
    • Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining similar to 14% of the familial risk of the disease. To identify new susceptibility loci, we performed a meta-analysis of 11 GWAS, comprising 15,748 breast cancer cases and 18,084 controls together with 46,785 cases and 42,892 controls from 41 studies genotyped on a 211,155-marker custom array (iCOGS). Analyses were restricted to women of European ancestry. We generated genotypes for more than 11 million SNPs by imputation using the 1000 Genomes Project reference panel, and we identified 15 new loci associated with breast cancer at P < 5 x 10(-8). Combining association analysis with ChIP-seq chromatin binding data in mammary cell lines and ChIA-PET chromatin interaction data from ENCODE, we identified likely target genes in two regions: SETBP1 at 18q12.3 and RNF115 and PDZK1 at 1q21.1. One association appears to be driven by an amino acid substitution encoded in EXO1.
  •  
8.
  • Phelan, Catherine M, et al. (författare)
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
  • 2017
  • Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 49:5, s. 680-691
  • Tidskriftsartikel (refereegranskat)abstract
    • To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC. This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31. Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.
  •  
9.
  • Forskningsöversikt (refereegranskat)
  •  
10.
  • Tidskriftsartikel (refereegranskat)
  •  
Skapa referenser, mejla, bekava och länka
Typ av publikation
tidskriftsartikel (167)
forskningsöversikt (2)
annan publikation (1)
Typ av innehåll
refereegranskat (166)
övrigt vetenskapligt (4)
Författare/redaktör
Brenner, H (62)
Zheng, W. (57)
Easton, DF (57)
Giles, GG (56)
Chang-Claude, J (56)
Lubinski, J (51)
visa fler...
Nevanlinna, H (47)
Wang, Q (47)
Chenevix-Trench, G (47)
Lindblom, A (46)
Lambrechts, D (46)
Hopper, JL (45)
Fasching, PA (45)
Milne, RL (45)
Southey, MC (44)
Wu, AH (44)
Garcia-Closas, M (44)
Dork, T (44)
Haiman, CA (43)
Couch, FJ (43)
Jakubowska, A (43)
Pharoah, PDP (43)
Benitez, J. (42)
Hamann, U (42)
Dennis, J (41)
Shu, XO (41)
Hall, P (41)
Andrulis, IL (41)
Cox, A (41)
Mannermaa, A (41)
Le Marchand, L (41)
Brauch, H (40)
Schmidt, MK (40)
Beckmann, MW (40)
Czene, K (39)
Dunning, AM (39)
Guenel, P (39)
Winqvist, R (39)
Chanock, SJ (38)
Margolin, S (38)
Burwinkel, B (38)
Bojesen, SE (38)
Kosma, VM (38)
Radice, P (37)
Bolla, MK (36)
Simard, J (36)
Devilee, P (36)
Lissowska, J (36)
Michailidou, K (35)
Easton, Douglas F. (35)
visa färre...
Lärosäte
Karolinska Institutet (119)
Lunds universitet (46)
Uppsala universitet (38)
Umeå universitet (30)
Göteborgs universitet (11)
Kungliga Tekniska Högskolan (9)
visa fler...
Högskolan Dalarna (4)
Linköpings universitet (3)
Chalmers tekniska högskola (3)
Stockholms universitet (2)
Örebro universitet (2)
Mittuniversitetet (1)
Blekinge Tekniska Högskola (1)
visa färre...
Språk
Engelska (170)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (86)
Naturvetenskap (14)
Samhällsvetenskap (4)
Teknik (1)

År

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy