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Sökning: WFRF:(Wu Ying Yu) > Stockholms universitet

  • Resultat 1-5 av 5
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  • 2019
  • Tidskriftsartikel (refereegranskat)
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  • Wu, Wei, et al. (författare)
  • Association of life satisfaction with disability-free survival : role of chronic diseases and healthy lifestyle
  • 2021
  • Ingår i: Age and Ageing. - : Oxford University Press (OUP). - 0002-0729 .- 1468-2834. ; 50:5, s. 1657-1665
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: this article investigates the association between life satisfaction and disability-free survival, and explores the roles of chronic diseases and healthy lifestyle in this association.Method: a cohort of 2,116 functionally independent adults aged >= 60 was followed up to 12 years. At baseline, life satisfaction was assessed with the Life Satisfaction Index A (LSI-A). Disability-free survival was defined as the survival till the first occurrence of either death, dementia or physical disability. Information on lifestyle factors was collected via questionnaire. Chronic diseases were ascertained through clinical examinations at baseline and each follow-up. Data were analysed using Cox proportional hazard regression models and Laplace regression.Results: over follow-up, 1,121 participants died, developed dementia, or became disabled. High LSI-A versus Low LSI-A had a lower risk of death, dementia and physical disability (hazard ratio [HR] 0.79, 95% confidence intervals [CI] 0.67-0.94), and had a longer disability-free period by 1.73 (95% CI 0.18-3.32) years. In mediation analysis, accumulation of chronic diseases mediated 17.8% of the association between LSI-A and disability-free survival. In joint effect analysis, participants with high LSI-A and a favourable lifestyle profile had a HR of 0.53 (95% CI 0.41-0.69) for the composite endpoint, and lived 3.2 (95% CI 1.35-5.11) disability-free years longer than those with low life satisfaction and an unfavourable lifestyle profile.Discussion: high life satisfaction is independently associated with longer disability-free survival. This association is partially mediated by a lower burden of chronic diseases and is reinforced by healthy lifestyle.
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  • Wu, Wei, et al. (författare)
  • Can health behaviours prolong survival and compress the period of survival with the disability? A population-based cohort study
  • 2021
  • Ingår i: Age and Ageing. - : Oxford University Press (OUP). - 0002-0729 .- 1468-2834. ; 50:2, s. 480-487
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: It remains unclear whether and to what extent health behaviours may prolong survival and compress the period of survival with disability.Objective: To identify modifiable health behaviours that are associated with later disability onset and longer disability-free survival.Design: This population-based cohort study used data from the Swedish National Study on Ageing and Care in Kungsholmen (SNAC-K) ranging between 2001 and 2016.Setting and subjects: A total of 3,041 disability-free adults aged >= 60 years were followed up to 15 years. Methods: Data on health behaviours were collected at baseline. Information on limitations in activities of daily living was obtained at baseline and during the follow-up. Laplace regression was used to model the median age at death and disability occurrence as a function of health behaviours.Results: Never smoking, moderate alcohol drinking, rich social network and high leisure activity were individually related to longer survival by 1-3 years. Participants with high leisure activity lived 1.6 years (95% CI: 0.9-2.3) more without a disability. After combining lifestyle factors, social network, and leisure activities into a 4-level `health behaviour profile', people with the healthiest behaviour profile lived 2.8 years (95% CI: 1.3-4.2) longer, had disability 3.5 years (95% CI: 1.7-5.3) later and lived 0.7 years (95% CI, 0.4-1.1) more without a disability compared to those with the least healthy behaviours profile.Conclusions: These findings suggest that health behaviours could prolong the lifespan, and leisure activities may further compress years lived with disability among older adults.
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