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Sökning: WFRF:(Yan Hongbing)

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  • Chen, Yundai, et al. (författare)
  • Treatment Trends, Effectiveness, and Safety of Statins on Lipid Goal Attainment in Chinese Percutaneous Coronary Intervention Patients : a Multicenter, Retrospective Cohort Study
  • 2017
  • Ingår i: Clinical Therapeutics. - : ELSEVIER. - 0149-2918 .- 1879-114X. ; 39:9, s. 1827-1839
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: Limited data exist on the use of statins in Chinese patients with coronary artery disease (CAD) treated with percutaneous coronary intervention (PCI). We therefore conducted this study to observe the usage trend and the effectiveness of statins on LDL-C goal attainment and other lipid parameters among PCI-treated patients.Methods: This multicenter, retrospective, observational, longitudinal cohort study was conducted in PCI-treated patients with CAD between July 1, 2011, and February 28, 2015. Primary study outcomes included statin treatment pattern after PCI and proportion of patients achieving target (LDL-C) levels 1 month after PCI and initiating statin therapy.Findings: Data were analyzed for 2708 patients (mean age, 59 [10] years; median body mass index, 25.6 [4.0] kg/m(2)). From baseline to the end of 1 month, atorvastatin and rosuvastatin were the most prescribed statins; 20 mg and 10 mg were the most prescribed doses and therefore chosen for efficacy comparisons. In patients without dose changes, LDL-C reduction with rosuvastatin 10 mg was significantly greater compared with atorvastatin 20 mg (-0.67 mmol/L [from 2.44 mmol/L to 1.77 mmol/L] vs 0.54 mmol/L [from 2.40 mmol/L to 1.86 mmol/L]; P = 0.008). However, there was no difference in HDL-C, triglyceride, or total cholesterol values between groups. Age and LDL-C levels at baseline were significantly associated with target LDL-C achievement.
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  • Qu, Hui-Ying, et al. (författare)
  • Cation-/Anion-Based Physicochemical Mechanisms for Anodically-Coloring Electrochromic Nickel Oxide Thin Films
  • 2022
  • Ingår i: ChemElectroChem. - : John Wiley & Sons. - 2196-0216. ; 9:7
  • Tidskriftsartikel (refereegranskat)abstract
    • The rapidly expanding field of intelligent ion-based devices has increased interest in the use of anodically-coloring electrochromic nickel oxide thin films. The degradation and coloration mechanisms of nickel oxide, especially in Li+-based electrolytes, are yet to be well understood. Herein we demonstrate that high potentials have a positive effect on the electrochromic performance of nickel oxide thin films. Our studies show that Cl- ions involved in the electrochromic process have been accumulated on the surface of the films upon extended electrochemical cycling, as confirmed by the X-ray Photoelectron Spectroscopy. X-ray Absorption Spectroscopy results indicate that the formation of Ni-Cl bonds influence the structural distortion and that the hybridization between Ni 3d and O 2p orbitals has been enhanced. Density functional theory calculations provide further insights for the band structures and how they change when Li+ and Cl- are adsorbed. Our results have revealed the underlying physical and chemical origins associated with the coloration mechanism and the degradation of nickel oxide thin films and highlighted the key role of Cl-. These new understandings will advance the development of superior electrochromic materials and the designing of efficient and durable electrochromic devices, both experimentally and theoretically.
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