SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Young Allan H.) "

Sökning: WFRF:(Young Allan H.)

  • Resultat 1-10 av 43
  • [1]2345Nästa
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Ahrens, Maryon, et al. (författare)
  • Neutrino oscillation studies with IceCube-DeepCore
  • 2016
  • Ingår i: Nuclear Physics B. - 0550-3213 .- 1873-1562. ; 908, s. 161-177
  • Tidskriftsartikel (refereegranskat)abstract
    • IceCube, a gigaton-scale neutrino detector located at the South Pole, was primarily designed to search for astrophysical neutrinos with energies of PeV and higher. This goal has been achieved with the detection of the highest energy neutrinos to date. At the other end of the energy spectrum, the DeepCore extension lowers the energy threshold of the detector to approximately 10 GeV and opens the door for oscillation studies using atmospheric neutrinos. An analysis of the disappearance of these neutrinos has been completed, with the results produced being complementary with dedicated oscillation experiments. Following a review of the detector principle and performance, the method used to make these calculations, as well as the results, is detailed. Finally, the future prospects of IceCube-DeepCore and the next generation of neutrino experiments at the South Pole (IceCube-Gen2, specifically the PINGU sub-detector) are briefly discussed.
2.
  • Aartsen, M. G., et al. (författare)
  • Search for astrophysical tau neutrinos in three years of IceCube data
  • 2016
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 93:2
  • Tidskriftsartikel (refereegranskat)abstract
    • The IceCube Neutrino Observatory has observed a diffuse flux of TeV-PeVastrophysical neutrinos at 5.7 sigma significance from an all-flavor search. The direct detection of tau neutrinos in this flux has yet to occur. Tau neutrinos become distinguishable from other flavors in IceCube at energies above a few hundred TeV, when the cascade from the tau neutrino charged current interaction becomes resolvable from the cascade from the tau lepton decay. This paper presents results from the first dedicated search for tau neutrinos with energies between 214 TeV and 72 PeV in the full IceCube detector. The analysis searches for IceCube optical sensors that observe two separate pulses in a single event-one from the tau neutrino interaction and a second from the tau decay. No candidate events were observed in three years of IceCube data. For the first time, a differential upper limit on astrophysical tau neutrinos is derived around the PeV energy region, which is nearly 3 orders of magnitude lower in energy than previous limits from dedicated tau neutrino searches.
  •  
3.
  • Adrian-Martinez, S., et al. (författare)
  • The First Combined Search For Neutrino Point-Sources In The Southern Hemisphere With The Antares And Icecube Neutrino Telescopes
  • 2016
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 823:1
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the results of searches for point-like sources of neutrinos based on the first combined analysis of data from both the ANTARES and IceCube neutrino telescopes. The combination of both detectors, which differ in size and location, forms a window in the southern sky where the sensitivity to point sources improves by up to a factor of 2 compared with individual analyses. Using data recorded by ANTARES from 2007 to 2012, and by IceCube from 2008 to 2011, we search for sources of neutrino emission both across the southern sky and from a preselected list of candidate objects. No significant excess over background has been found in these searches, and flux upper limits for the candidate sources are presented for E-2.5 and E-2 power-law spectra with different energy cut-offs.
  •  
4.
  • Ahrens, Maryon, et al. (författare)
  • Flavor Ratio of Astrophysical Neutrinos above 35 TeV in IceCube
  • 2015
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 114:17
  • Tidskriftsartikel (refereegranskat)abstract
    • A diffuse flux of astrophysical neutrinos above 100 TeV has been observed at the IceCube Neutrino Observatory. Here we extend this analysis to probe the astrophysical flux down to 35 TeV and analyze its flavor composition by classifying events as showers or tracks. Taking advantage of lower atmospheric backgrounds for showerlike events, we obtain a shower-biased sample containing 129 showers and 8 tracks collected in three years from 2010 to 2013. We demonstrate consistency with the (f(e) : f(mu) : f(tau))(circle plus) approximate to (1 : 1 : 1)(circle plus) flavor ratio at Earth commonly expected from the averaged oscillations of neutrinos produced by pion decay in distant astrophysical sources. Limits are placed on nonstandard flavor compositions that cannot be produced by averaged neutrino oscillations but could arise in exotic physics scenarios. A maximally tracklike composition of (0 : 1 : 0)(circle plus) is excluded at 3.3 sigma, and a purely showerlike composition of (1 : 0 : 0)(circle plus) is excluded at 2.3 sigma.
  •  
5.
  • Kankare, E., et al. (författare)
  • Search for transient optical counterparts to high-energy IceCube neutrinos with Pan-STARRS1
  • 2019
  • Ingår i: Astronomy and Astrophysics. - EDP Sciences. - 0004-6361 .- 1432-0746. ; 626
  • Tidskriftsartikel (refereegranskat)abstract
    • In order to identify the sources of the observed diffuse high-energy neutrino flux, it is crucial to discover their electromagnetic counterparts. To increase the sensitivity of detecting counterparts of transient or variable sources by telescopes with a limited field of view, IceCube began releasing alerts for single high-energy (E-v > 60 TeV) neutrino detections with sky localisation regions of order 1 degrees radius in 2016. We used Pan-STARRS1 to follow-up five of these alerts during 2016-2017 to search for any optical transients that may be related to the neutrinos. Typically 10-20 faint m(ip1) less than or similar to 22.5 mag) extragalactic transients are found within the Pan-STARRS1 footprints and are generally consistent with being unrelated field supernovae (SNe) and AGN. We looked for unusual properties of the detected transients, such as temporal coincidence of explosion epoch with the IceCube timestamp, or other peculiar light curve and physical properties. We found only one transient that had properties worthy of a specific follow-up. In the Pan-STARRS1 imaging for IceCube-160427A (probability to be of astrophysical origin of similar to 50%), we found a SN PS16cgx, located at 10.0' from the nominal IceCube direction. Spectroscopic observations of PS16cgx showed that it was an H-poor SN at redshift z = 0.2895 +/- 0.0001. The spectra and light curve resemble some high-energy Type Ic SNe, raising the possibility of a jet driven SN with an explosion epoch temporally coincident with the neutrino detection. However, distinguishing Type Ia and Type Ic SNe at this redshift is notoriously difficult. Based on all available data we conclude that the transient is more likely to be a Type Ia with relatively weak Sin absorption and a fairly normal rest-frame r-band light curve. If, as predicted, there is no high-energy neutrino emission from Type Ia SNe, then PS16cgx must be a random coincidence, and unrelated to the IceCube-160427A. We find no other plausible optical transient for any of the five IceCube events observed down to a 5 sigma limiting magnitude of mip1 approximate to 22 mag, between 1 day and 25 days after detection.
  •  
6.
  • Aartsen, M. G., et al. (författare)
  • Determining neutrino oscillation parameters from atmospheric muon neutrino disappearance with three years of IceCube DeepCore data
  • 2015
  • Ingår i: Physical Review D. - 1550-7998. ; 91:7
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a measurement of neutrino oscillations via atmospheric muon neutrino disappearance with three years of data of the completed IceCube neutrino detector. DeepCore, a region of denser IceCube instrumentation, enables the detection and reconstruction of atmospheric muon neutrinos between 10 and 100 GeV, where a strong disappearance signal is expected. The IceCube detector volume surrounding DeepCore is used as a veto region to suppress the atmospheric muon background. Neutrino events are selected where the detected Cherenkov photons of the secondary particles minimally scatter, and the neutrino energy and arrival direction are reconstructed. Both variables are used to obtain the neutrino oscillation parameters from the data, with the best fit given by Delta m(32)(2) = 2.72(-0.20)(+0.19) x 10(-3) eV(2) and sin(2)theta(23) = 0.53(-0.12)(+0.09) (normal mass ordering assumed). The results are compatible, and comparable in precision, to those of dedicated oscillation experiments.
  •  
7.
  • Ahrens, Maryon, et al. (författare)
  • Neutrino emission from the direction of the blazar TXS 0506+056 prior to the IceCube-170922A alert
  • 2018
  • Ingår i: Science. - 0036-8075 .- 1095-9203. ; 361:6398, s. 147-151
  • Tidskriftsartikel (refereegranskat)abstract
    • A high-energy neutrino event detected by IceCube on 22 September 2017 was coincident in direction and time with a gamma-ray flare from the blazar TXS 0506+056. Prompted by this association, we investigated 9.5 years of IceCube neutrino observations to search for excess emission at the position of the blazar. We found an excess of high-energy neutrino events, with respect to atmospheric backgrounds, at that position between September 2014 and March 2015. Allowing for time-variable flux, this constitutes 3.5 sigma evidence for neutrino emission from the direction of TXS 0506+056, independent of and prior to the 2017 flaring episode. This suggests that blazars are identifiable sources of the high-energy astrophysical neutrino flux.
  •  
8.
  • Aartsen, M. G., et al. (författare)
  • Astrophysical neutrinos and cosmic rays observed by IceCube
  • 2018
  • Ingår i: Advances in Space Research. - 0273-1177 .- 1879-1948. ; 62:10, s. 2902-2930
  • Tidskriftsartikel (refereegranskat)abstract
    • The core mission of the IceCube neutrino observatory is to study the origin and propagation of cosmic rays. IceCube, with its surface component IceTop, observes multiple signatures to accomplish this mission. Most important are the astrophysical neutrinos that are produced in interactions of cosmic rays, close to their sources and in interstellar space. IceCube is the first instrument that measures the properties of this astrophysical neutrino flux and constrains its origin. In addition, the spectrum, composition, and anisotropy of the local cosmic-ray flux are obtained from measurements of atmospheric muons and showers. Here we provide an overview of recent findings from the analysis of IceCube data, and their implications to our understanding of cosmic rays.
  •  
9.
  • Turcot, Valérie, et al. (författare)
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
  • 2018
  • Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 50:1, s. 26-
  • Tidskriftsartikel (refereegranskat)abstract
    • Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains challenging. Here we combined data from 718,734 individuals to discover rare and low-frequency (minor allele frequency (MAF) < 5%) coding variants associated with BMI. We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHE, RAPGEF3, RAB21, ZFHX3, ENTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in genes (MC4R and KSR2) previously observed to be mutated in extreme obesity and 2 variants were in GIPR. The effect sizes of rare variants are ~10 times larger than those of common variants, with the largest effect observed in carriers of an MC4R mutation introducing a stop codon (p.Tyr35Ter, MAF = 0.01%), who weighed ~7 kg more than non-carriers. Pathway analyses based on the variants associated with BMI confirm enrichment of neuronal genes and provide new evidence for adipocyte and energy expenditure biology, widening the potential of genetically supported therapeutic targets in obesity.
  •  
10.
  • Kato, Norihiro, et al. (författare)
  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
  • 2015
  • Ingår i: Nature Genetics. - Nature Publishing Group. - 1546-1718. ; 47:11, s. 93-1282
  • Tidskriftsartikel (refereegranskat)abstract
    • We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10(-11) to 5.0 × 10(-21)). The sentinel blood pressure SNPs are enriched for association with DNA methylation at multiple nearby CpG sites, suggesting that, at some of the loci identified, DNA methylation may lie on the regulatory pathway linking sequence variation to blood pressure. The sentinel SNPs at the 12 new loci point to genes involved in vascular smooth muscle (IGFBP3, KCNK3, PDE3A and PRDM6) and renal (ARHGAP24, OSR1, SLC22A7 and TBX2) function. The new and known genetic variants predict increased left ventricular mass, circulating levels of NT-proBNP, and cardiovascular and all-cause mortality (P = 0.04 to 8.6 × 10(-6)). Our results provide new evidence for the role of DNA methylation in blood pressure regulation.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 43
  • [1]2345Nästa
Åtkomst
fritt online (11)
Typ av publikation
tidskriftsartikel (41)
konferensbidrag (1)
forskningsöversikt (1)
Typ av innehåll
refereegranskat (43)
Författare/redaktör
Linneberg, Allan, (16)
Grarup, Niels, (16)
Pedersen, Oluf, (16)
Hansen, Torben, (16)
Boehnke, Michael (16)
Scott, Robert A (16)
visa fler...
Esko, Tonu (16)
McCarthy, Mark I (15)
Langenberg, Claudia (15)
Metspalu, Andres (15)
Mahajan, Anubha (15)
Wareham, Nicholas J. (14)
Kuusisto, Johanna, (14)
Laakso, Markku, (14)
Mohlke, Karen L (14)
Chambers, John C. (14)
Salomaa, Veikko (13)
Peters, Annette (13)
Strauch, Konstantin (13)
Morris, Andrew P. (13)
Tuomilehto, Jaakko (13)
Zhang, Weihua (13)
Lind, Lars, (12)
Stancáková, Alena, (12)
Jackson, Anne U. (12)
Collins, Francis S. (12)
Frayling, Timothy M. (12)
Rauramaa, Rainer (12)
Grallert, Harald (12)
Froguel, Philippe, (11)
Uitterlinden, Andre ... (11)
Jorgensen, Torben (11)
Barroso, Ines (11)
Luan, Jian'an (11)
Stringham, Heather M ... (11)
Loos, Ruth J. F. (11)
Lindgren, Cecilia M. (11)
Mueller-Nurasyid, Ma ... (11)
Raitakari, Olli T (10)
Deloukas, Panos (10)
Bork-Jensen, Jette, (10)
Brandslund, Ivan, (10)
Saleheen, Danish, (10)
Gieger, Christian (10)
Hattersley, Andrew T (10)
Hayward, Caroline (10)
Karpe, Fredrik, (10)
Zeggini, Eleftheria (10)
Balkau, Beverley (10)
Kooner, Jaspal S. (10)
visa färre...
Lärosäte
Uppsala universitet (26)
Lunds universitet (19)
Umeå universitet (18)
Stockholms universitet (9)
Karolinska Institutet (9)
Göteborgs universitet (8)
visa fler...
Linköpings universitet (1)
Sveriges Lantbruksuniversitet (1)
Chalmers tekniska högskola (1)
visa färre...
Språk
Engelska (43)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (30)
Naturvetenskap (17)

År

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy