Sökning: WFRF:(Yu Jin)
> VTI - Statens väg- och transportforskningsinstitut >
Genomewide Associat...
Genomewide Association Study on Fallible Behavior of Accident-Repeated Drivers in China
-
- Jin, Hui-qing (författare)
- Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China
-
- Zhang, Shu-lin (författare)
- Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China
-
- Song, Yang (författare)
- Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China
-
visa fler...
-
- Yu, Wan-sheng (författare)
- Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China
-
visa färre...
-
(creator_code:org_t)
- Linköping : Statens väg- och transportforskningsinstitut, 2013
- 2013
- Engelska.
-
Ingår i: Proceedings of the 16th International Conference Road Safety on Four Continents. - Linköping : Statens väg- och transportforskningsinstitut.
- Relaterad länk:
-
https://vti.diva-por... (primary) (Raw object)
-
visa fler...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- Driving behavior of a driver is closely related to traffic accidents, and is controlled by nervous system. Gene expression in the nervous cells may indirectly affect people's behavior. In order to explore genetic basis of fallible behavior of the accident-repeated drivers, in accordance with the Chinese national standard "Physical qualifications for automobile drivers and their test protocol" (GB18463-2001), these drivers whose indexes were all abnormal were chose as candidates of case, and those whose indexes were all normal were chose as candidates of control. A total of 232 matching pairs of drivers were selected. We chose above case candidates who had three or more accidents at the level of more than equal-responsibility within 5 consecutive years (2005-2009) as case group. The control candidates who did not have liability for accidents over the same years (2005-2009) as control group, 179 matching pairs of drivers has been chosen as sample. GWAS (Genome-wide association study) are applied to 179 pairs of matching samples on fallible behavior of drivers. The result showed that 31 SNPs loci in 3 linked genes (SMAD5,TRPC7(P<10-4)and CBLN4 (P<10-5) ) are associated with fallible behavior of drivers .The current study suggested for the first time the potential association between the fallible behavior and the potential susceptible genes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
Nyckelord
- Accident proneness
- Medical aspects
- 84 Road: Road users
- 84 Road: Road users
- X RSXC
- X RSXC
Publikations- och innehållstyp
- vet (ämneskategori)
- kon (ämneskategori)