| 1. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 4. |
- Dai, Qile, et al.
(författare)
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OTTERS: a powerful TWAS framework leveraging summary-level reference data
- 2023
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- Most existing TWAS tools require individual-level eQTL reference data and thus are not applicable to summary-level reference eQTL datasets. The development of TWAS methods that can harness summary-level reference data is valuable to enable TWAS in broader settings and enhance power due to increased reference sample size. Thus, we develop a TWAS framework called OTTERS (Omnibus Transcriptome Test using Expression Reference Summary data) that adapts multiple polygenic risk score (PRS) methods to estimate eQTL weights from summary-level eQTL reference data and conducts an omnibus TWAS. We show that OTTERS is a practical and powerful TWAS tool by both simulations and application studies.
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| 5. |
- Wang, Zeng, et al.
(författare)
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Zeolite coated ATR crystals for new applications in FTIR-ATR spectroscopy
- 2004
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; :24, s. 2888-2889
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Tidskriftsartikel (refereegranskat)abstract
- Thin silicalite-1 films were grown on ATR crystals and used for detection of low amounts of organic molecules in a gas flow by FTIR spectroscopy.
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| 6. |
- Zeng, L.F., et al.
(författare)
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Adaptive finite element procedure for 2D dynamic transient analysis using direct integration
- 1992
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Ingår i: International Journal for Numerical Methods in Engineering. - : Wiley. - 0029-5981 .- 1097-0207. ; 34:3, s. 997-1014
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Tidskriftsartikel (refereegranskat)abstract
- An adaptive h-version finite element procedure is presented for a 2D elastodynamic transient analysis using direct integration. The procedure modifies the spatial discretization, i.e. the mesh, in time so that the spatial discretization error can be controlled in each time instant. We analyse an a priori error estimate for the total energy which shows that an a posteriori error estimate developed by Zienkiewicz and Zhu for linear elastostatics can reasonably be extended to dynamic transient analysis. For the time integration, both explicit and implicit time integration schemes can be coupled with the procedure. However, the study in this paper is confined to the use of the Newmark scheme. Numerical examples are used to study the performance of the error estimate and to illustrate the adaptive procedure. Obtained numerical results indicate that: (i) the extension of the Zienkiewicz-Zhu estimate to dynamic transient analysis is useful; (ii) the presented adaptive procedure can, in an efficient way, provide a finite element solution with a user-controlled accuracy.
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