| 1. |
-
- 2019
-
Tidskriftsartikel (refereegranskat)
|
|
| 2. |
- Kristan, Matej, et al.
(författare)
-
The Ninth Visual Object Tracking VOT2021 Challenge Results
- 2021
-
Ingår i: 2021 IEEE/CVF INTERNATIONAL CONFERENCE ON COMPUTER VISION WORKSHOPS (ICCVW 2021). - : IEEE COMPUTER SOC. - 9781665401913 ; , s. 2711-2738
-
Konferensbidrag (refereegranskat)abstract
- The Visual Object Tracking challenge VOT2021 is the ninth annual tracker benchmarking activity organized by the VOT initiative. Results of 71 trackers are presented; many are state-of-the-art trackers published at major computer vision conferences or in journals in recent years. The VOT2021 challenge was composed of four sub-challenges focusing on different tracking domains: (i) VOT-ST2021 challenge focused on short-term tracking in RGB, (ii) VOT-RT2021 challenge focused on "real-time" short-term tracking in RGB, (iii) VOT-LT2021 focused on long-term tracking, namely coping with target disappearance and reappearance and (iv) VOT-RGBD2021 challenge focused on long-term tracking in RGB and depth imagery. The VOT-ST2021 dataset was refreshed, while VOT-RGBD2021 introduces a training dataset and sequestered dataset for winner identification. The source code for most of the trackers, the datasets, the evaluation kit and the results along with the source code for most trackers are publicly available at the challenge website(1).
|
|
| 3. |
- Luo, Yifei, et al.
(författare)
-
Technology Roadmap for Flexible Sensors
- 2023
-
Ingår i: ACS Nano. - : American Chemical Society. - 1936-0851 .- 1936-086X. ; 17:6, s. 5211-5295
-
Forskningsöversikt (refereegranskat)abstract
- Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensors and propose promising solutions. We first analyze challenges in achieving satisfactory sensing performance for real-world applications and then summarize issues in compatible sensor-biology interfaces, followed by brief discussions on powering and connecting sensor networks. Issues en route to commercialization and for sustainable growth of the sector are also analyzed, highlighting environmental concerns and emphasizing nontechnical issues such as business, regulatory, and ethical considerations. Additionally, we look at future intelligent flexible sensors. In proposing a comprehensive roadmap, we hope to steer research efforts towards common goals and to guide coordinated development strategies from disparate communities. Through such collaborative efforts, scientific breakthroughs can be made sooner and capitalized for the betterment of humanity.
|
|
| 4. |
- Zhang, Guojie, et al.
(författare)
-
Comparative genomics reveals insights into avian genome evolution and adaptation
- 2014
-
Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 346:6215, s. 1311-1320
-
Tidskriftsartikel (refereegranskat)abstract
- Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. The avian genome is principally characterized by its constrained size, which predominantly arose because of lineage-specific erosion of repetitive elements, large segmental deletions, and gene loss. Avian genomes furthermore show a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synteny, and chromosomal structure. Despite this pattern of conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncoding regions. These analyses reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.
|
|
| 5. |
- Hu, Hai-Xi, et al.
(författare)
-
Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation
- 2015
-
Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 5
-
Tidskriftsartikel (refereegranskat)abstract
- The one-dimensional pattern of heterocyst in the model cyanobacterium Anabaena sp. PCC 7120 is coordinated by the transcription factor HetR and PatS peptide. Here we report the complex structures of HetR binding to DNA, and its hood domain (HetR(Hood)) binding to a PatS-derived hexapeptide (PatS6) at 2.80 and 2.10 angstrom, respectively. The intertwined HetR dimer possesses a couple of novel HTH motifs, each of which consists of two canonical alpha-helices in the DNA-binding domain and an auxiliary alpha-helix from the flap domain of the neighboring subunit. Two PatS6 peptides bind to the lateral clefts of HetR(Hood), and trigger significant conformational changes of the flap domain, resulting in dissociation of the auxiliary alpha-helix and eventually release of HetR from the DNA major grove. These findings provide the structural insights into a prokaryotic example of Turing model.
|
|
| 6. |
- Zhang, Daquan, et al.
(författare)
-
Large-scale planar and spherical light-emitting diodes based on arrays of perovskite quantum wires
- 2022
-
Ingår i: Nature Photonics. - : Springer Science and Business Media LLC. - 1749-4885 .- 1749-4893. ; 16:4, s. 284-290
-
Tidskriftsartikel (refereegranskat)abstract
- Halide perovskites are enticing candidates for highly efficient planar light-emitting diodes (LEDs) with commercial potential in displays and lighting. However, it remains a challenge for conventional solution fabrication processes to fabricate large-scale or non-planar LEDs due to the non-uniformity of perovskite films in conjunction with material stability issues. Here large-area highly uniform arrays of crystalline perovskite quantum wires are grown with emission spectra covering the whole visible range. Photoluminescence quantum yield of up to 92% and 5,644 hours as the time for photoluminescence to degrade down to its 50% of the initial value under ambient conditions are achieved for MAPbBr3 quantum wires. LEDs based on these quantum wires on rigid and flexible planar substrates are fabricated up to a four-inch wafer size and also unique three-dimensional spherical LEDs with outstanding uniformity are reported. The results suggest that the approach developed here can be generalized to other unconventional three-dimensional LEDs in the future.
|
|
| 7. |
- Zhao, Zeng-Ren, et al.
(författare)
-
Overexpression of Id-1 protein is a marker in colorectal cancer progression
- 2008
-
Ingår i: Oncology Reports. - : Spandidos. - 1021-335X .- 1791-2431. ; 19:2, s. 419-424
-
Tidskriftsartikel (refereegranskat)abstract
- Abstract: The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an important role in the regulation of cell proliferation and differentiation. We examined the Id-1 expression by immunohistochemistry in 9 adenomas, 79 primary colorectal adenocarcinomas matched with 40 adjacent normal mucosa specimens and its relationship with clinicopathological factors. The Id-1 expression was increased in the carcinoma compared to the adjacent normal mucosa either in the unmatched and matched samples or to the adenoma. There was no significant difference in the Id-1 expression between normal mucosa and adenoma. The Id-1 expression of carcinoma was increased from Dukes' stages A to B, to C and to D. The cases with lymph node metastasis had a higher rate of a stronger Id-1 expression than those without lymph node metastasis. In conclusion, Id-1 overexpression plays an important role in colorectal cancer progression.
|
|
| 8. |
- Lin, Li'na, et al.
(författare)
-
GEOCHRONOLOGIC AND GEOCHEMICAL EVIDENCE FOR PERSISTENCE OF SOUTH-DIPPING SUBDUCTION TO LATE PERMIAN TIME, LANGSHAN AREA, INNER MONGOLIA (CHINA) : SIGNIFICANCE FOR TERMINATION OF ACCRETIONARY OROGENESIS IN THE SOUTHERN ALTAIDS
- 2014
-
Ingår i: American Journal of Science. - : American Journal of Science (AJS). - 0002-9599 .- 1945-452X. ; 314:2, s. 679-703
-
Tidskriftsartikel (refereegranskat)abstract
- The Langshan area in Inner Mongolia is situated in the southern Altaids between the Beishan suture to the west and the Solonker suture to the east. This paper addresses the poorly known tectonic evolution that led to formation of the terminal Solonker suture. Dating of deformed porphyries and undeformed dolerites and gabbros constrains the timing of the relevant NE-E-striking and north-vergent deformation. Deformed granitic-granodioritic porphyries in this area are characterized by high SiO2 (65.38-78.00%), low TFe2O3 (1.29-5.07%), MgO (0.13-0.63%), and variable K2O (0.534.14%) and Na2O (2.05-4.62%). All samples have enriched LREE (La/Yb 6-18) and negative Nb anomalies (Nb-N/Th(N)0.09-0.48), but different Eu anomalies (Eu* <0.7 or similar to 1); these geochemical features can be ascribed to a heterogeneous source in a subduction-related environment. Gabbros and dolerites have 42.33 to 52.03 percent SiO2. All mafic samples have similar La/Yb ratios of 4 to 6 and negative Nb anomalies (Nb-N/Th-N) ratios of 0.2 to 0.8, suggestive of a subduction-related setting. Two granitic porphyries yielded U-238/Pb-206 weighted mean ages of 284.7 +/- 2.1 Ma with MSWD of 1.6 and 291.7 +/- 2: 2.1 Ma with MSWD of 1.14; these ages are consistent with U-235/Pb-207 and U-238/Pb-206 concordia ages of 281 +/- 17 Ma with MSWD of 0.87 and 289.8 +/- 9.2 Ma with MSWD of 0.66. A dolerite yielded concordia ages of 256.2 +/- 2.6 Ma with MSWD of 0.44 and 256 +/- 2.5 Ma with MSWD 0.45. The ages and geochemistry of the deformed porphyries indicate that in the early Permian there was important deformation and recrystallization in a subduction-related setting. The isotopic and geochemical signatures of all the rocks indicate that they formed during subduction-related conditions. We propose that Langshan was a Permian active continental margin arc built on the edge of the North China Craton by southward subduction, which led to closure of the ocean, concomitant formation of the Solonker suture in the late Permian-early Triassic, and termination of the accretion-subduction orogen of the southern Altaids.
|
|
| 9. |
- Makafe, Gaelle G., et al.
(författare)
-
Quinoline Derivatives Kill Mycobacterium tuberculosis by Activating Glutamate Kinase
- 2019
-
Ingår i: Cell Chemical Biology. - : CELL PRESS. - 2451-9456 .- 2451-9448. ; 26:8, s. 1187-
-
Tidskriftsartikel (refereegranskat)abstract
- There is a great need for identification and development of new anti-tuberculosis drugs with novel targets. Recent drug-discovery efforts typically focus on identifying inhibitors but not activators that perturb metabolic enzymes' functions as a means to kill Mycobacterium tuberculosis (Mtb). Here, we describe a class of quinoline compounds, Z0933/Z0930, which kill Mtb by acting as activators of glutamate kinase (GK), a previously untargeted enzyme catalyzing the first step of proline biosynthesis. We further show that Z0933/Z0930 augment proline production and induce Mtb killing via proline-derived redox imbalance and production of reactive oxygen species. This work highlights the effectiveness of gain-of-function probes against Mtb and provides a framework for the discovery of next-generation allosteric activators of GK.
|
|
| 10. |
- Zhang, Peili, et al.
(författare)
-
Paired Electrocatalytic Oxygenation and Hydrogenation of Organic Substrates with Water as the Oxygen and Hydrogen Source
- 2019
-
Ingår i: Angewandte Chemie International Edition. - : Wiley-VCH Verlagsgesellschaft. - 1433-7851 .- 1521-3773. ; 58:27, s. 9155-9159
-
Tidskriftsartikel (refereegranskat)abstract
- The use of water as an oxygen and hydrogen source for the paired oxygenation and hydrogenation of organic substrates to produce valuable chemicals is of utmost importance as a means of establishing green chemical syntheses. Inspired by the active Ni3+ intermediates involved in electro-catalytic water oxidation by nickel-based materials, we prepared NiBx as a catalyst and used water as the oxygen source for the oxygenation of various organic compounds. NiBx was further employed as both an anode and a cathode in a paired electrosynthesis cell for the respective oxygenation and hydrogenation of organic compounds, with water as both the oxygen and hydrogen source. Conversion efficiency and selectivity of >= 99% were observed during the oxygenation of 5-hydroxy-methylfurfural to 2,5-furandicarboxylic acid and the simultaneous hydrogenation of p-nitrophenol to p-aminophenol. This paired electrosynthesis cell has also been coupled to a solar cell as a stand-alone reactor in response to sunlight.
|
|
