| 1. |
- Kaliyugarasan, Satheshkumar, et al.
(författare)
-
Multi-Center CNN-Based Spine Segmentation from T2W MRI Using Small Amounts of Data
- 2023
-
Ingår i: Proceedings - International Symposium on Biomedical Imaging. - 1945-7928 .- 1945-8452. - 9781665473583
-
Konferensbidrag (refereegranskat)abstract
- Segmentation of the spinal tissues on MRI is the basis for quantitative analyses, but time-consuming if done manually. In this work, we construct a pipeline for automatic vertebrae segmentation from T2w MRI scans, assessing performance and generalizability by external validation. Our study used 15 scans from one site (Haukeland University Hospital, HUH) and 10 scans from another (Sahlgrenska University Hospital, SUH). MRI experts manually delineated the vertebral bodies Th12-L5 on all the HUH data and a subset of six scans from SUH. We trained multiple convolutional neural networks, assessing the performance in an experimental design tailored to small-data contexts and also on external data. Our best model achieved a mean Dice score of 0.899. This is comparable to results in the literature, but our system required much less training data.
|
|
| 2. |
- Laurell, Katarina, et al.
(författare)
-
Premonitory symptoms in migraine : a cross-sectional study in 2714 persons
- 2016
-
Ingår i: Cephalalgia. - : SAGE Publications. - 0333-1024 .- 1468-2982. ; 36:10, s. 951-959
-
Tidskriftsartikel (refereegranskat)abstract
- AIM: To describe the frequency and number of premonitory symptoms (PS) in migraine, the co-occurrence of different PS, and their association with migraine-related factors.METHODS: In this cross-sectional study, a validated questionnaire was sent to Finnish migraine families between 2002 and 2013 to obtain data on 14 predefined PS, migraine diagnoses, demographic factors, and migraine characteristics. The estimated response rate was 80%.RESULTS: Out of 2714 persons, 2223 were diagnosed with migraine. Among these, 77% reported PS, with a mean number of 3.0 symptoms compared to 30% (p < 0.001) and 0.5 symptoms (p < 0.001) among 491 persons with non-migraine headaches. Yawning was the most commonly reported symptom (34%) among migraineurs. Females reported PS more frequently than males (81 versus 64%, p < 0.001) and experienced a higher number of different symptoms (mean 3.3 versus 1.8, p < 0.001). All measures of migraine severity were associated with a higher burden of PS. Light and sound sensitivity showed the highest co-occurrence (kappa = 0.51, 95% CI 0.47-0.55). In a generalized linear model, age, gender, higher frequency, duration and intensity of headache, reduced working capacity, most aura symptoms, and associated symptoms of the headache phase were significantly associated with an increased in the number of PS.CONCLUSION: PS are experienced by a majority of migraineurs. More severe migraine is associated with a higher burden of PS. Since the material was not entirely representative of the general population of migraineurs, caution should be exercised in generalizing the results.
|
|
| 3. |
|
|
| 4. |
- Tronvik, Erling, et al.
(författare)
-
The relationship between headache and religious attendance (the Nord-Trøndelag health study- HUNT)
- 2014
-
Ingår i: Journal of Headache and Pain. - : Springer. - 1129-2369 .- 1129-2377. ; 15
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Religious belief can be used as a pain coping strategy. Our purpose was to evaluate the relationship between headache and religious activity using prospective data from a large population-based study.METHODS: This longitudinal cohort study used data from two consecutive surveys in the Nord-Trøndelag Health Survey (HUNT 2 and 3) performed in 1995-1997; and 2006-2008. Among the 51,383 participants aged ≥ 20 years who answered headache questions at baseline, 41,766 were eligible approximately 11 years later. Of these, 25,177 (60%) completed the question in HUNT 3 regarding religious activity. Frequent religious attendees (fRA) (used as a marker of stronger religious belief than average) were defined as those who had been to church/prayer house at least once monthly during the last six months.RESULTS: In the multivariate analyses, adjusting for known potential confounders, individuals with headache 1-14 days/month in HUNT 2 were more likely to be fRA 11 years later than headache-free individuals. Migraine at baseline predisposed more strongly to fRA at follow-up (OR = 1.25; 95% CI 1.19-1.40) than did non-migrainous headache (OR = 1.13; 95% 1.04-1.23). The odds of being fRA was 48% increased (OR 1.48; 95% 1.19-1.83) among those with migraine 7-14 days/month at baseline compared to subjects without headache. In contrast, headache status at baseline did not influence the odds of being frequent visitors of concerts, cinema and/or theatre at follow-up 11 years later.CONCLUSIONS: In this prospective study, headache, in particular migraine, at baseline slightly increased the odds of being fRA 11 years later.
|
|
