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Träfflista för sökning "WFRF:(von Knorring Anne Liis 1945 ) "

Sökning: WFRF:(von Knorring Anne Liis 1945 )

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  • Bohman, Hannes, 1965-, et al. (författare)
  • Thicker carotid intima layer, thinner media layer and higher intima/media ratio in women with recurrent depressive disorders : a pilot study using non-invasive high frequency ultrasound
  • 2010
  • Ingår i: World Journal of Biological Psychiatry. - : Informa Healthcare. - 1562-2975 .- 1814-1412. ; 11:1, s. 71-75
  • Tidskriftsartikel (refereegranskat)abstract
    • Background. Growing evidence indicates that depression is an important risk factor for coronary heart disease. Thus, the aim of the present study has been to investigate if young women with adolescent onset and recurrent depressive disorders have signs of carotid intima and media changes already at the age of 30. Methods. Fifteen subjects with adolescent onset recurrent depressive disorders, mean age 31.5 years, were compared to 20 healthy women with a mean age of 39.6 years. The thickness of carotid artery intima and media was assessed, using non-invasive high-frequency ultrasound (25MHz). Results. The subjects with recurrent depressive disorders had significantly thicker carotid intima, significantly thinner carotid media and significantly higher intima/media ratio despite the fact that they were about 10 years younger than the healthy women. Hypertension, obesity or smoking could not explain the results. Conclusion. Already at the age of 30, subjects with recurrent depressive disorders with adolescent onset do have early signs of carotid intima and media changes, indicating a less healthy artery wall, despite otherwise no clinical signs of cardiovascular disease.
  • Alaie, Iman, et al. (författare)
  • Uppsala Longitudinal Adolescent Depression Study (ULADS)
  • 2019
  • Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055 .- 2044-6055. ; 9:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To present the Uppsala Longitudinal Adolescent Depression Study, initiated in Uppsala, Sweden, in the early 1990s. The initial aim of this epidemiological investigation was to study the prevalence, characteristics and correlates of adolescent depression, and has subsequently expanded to include a broad range of social, economic and health-related long-term outcomes and cost-of-illness analyses.Participants: The source population was first-year students (aged 16-17) in upper-secondary schools in Uppsala during 1991-1992, of which 2300 (93%) were screened for depression. Adolescents with positive screening and sex/age-matched peers were invited to a comprehensive assessment. A total of 631 adolescents (78% females) completed this assessment, and 409 subsequently completed a 15year follow-up assessment. At both occasions, extensive information was collected on mental disorders, personality and psychosocial situation. Detailed social, economic and health-related data from 1993 onwards have recently been obtained from the Swedish national registries for 576 of the original participants and an age-matched reference population (N=200 000).Findings to date: The adolescent lifetime prevalence of a major depressive episode was estimated to be 11.4%. Recurrence in young adulthood was reported by the majority, with a particularly poor prognosis for those with a persistent depressive disorder or multiple somatic symptoms. Adolescent depression was also associated with an increased risk of other adversities in adulthood, including additional mental health conditions, low educational attainment and problems related to intimate relationships.Future plans: Longitudinal studies of adolescent depression are rare and must be responsibly managed and utilised. We therefore intend to follow the cohort continuously by means of registries. Currently, the participants are approaching mid-adulthood. At this stage, we are focusing on the overall long-term burden of adolescent depression. For this purpose, the research group has incorporated expertise in health economics. We would also welcome extended collaboration with researchers managing similar datasets.
  • Ssegonja, Richard, et al. (författare)
  • Depressive disorders in adolescence, recurrence in early adulthood, and healthcare usage in mid-adulthood : A longitudinal cost-of-illness study
  • 2019
  • Ingår i: Journal of Affective Disorders. - : ELSEVIER. - 0165-0327 .- 1573-2517. ; 258, s. 33-41
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Depression in adolescence is associated with increased healthcare consumption in adulthood, but prior research has not recognized the heterogeneity of depressive disorders. This paper investigated the additional healthcare usage and related costs in mid-adulthood for individuals with adolescent depression, and examined the mediating role of subsequent depression in early adulthood.Methods: This study was based on the Uppsala Longitudinal Adolescent Depression Study, initiated in Sweden in the early 1990s. Depressive disorders were assessed in adolescence (age 16-17) and early adulthood (age 19-30). Healthcare usage and related costs in mid-adulthood (age 31-40) were estimated using nationwide population-based registries. Participants with specific subtypes of adolescent depression (n = 306) were compared with matched non-depressed peers (n = 213).Results: Women with persistent depressive disorder (PDD) in adolescence utilized significantly more healthcare resources in mid-adulthood. The association was not limited to psychiatric care, and remained after adjustment for individual and parental characteristics. The total additional annual cost for a single age group of females with a history of PDD at a population level was estimated at 3.10 million USD. Depression recurrence in early adulthood mediated the added costs for psychiatric care, but not for somatic care.Limitations: Primary health care data were not available, presumably resulting in an underestimation of the true healthcare consumption. Estimates for males had limited precision due to a relatively small male proportion.Conclusions: On a population level, the additional healthcare costs incurred in mid-adulthood in females with a history of adolescent PDD are considerable. Early treatment and prevention should be prioritized.
  • Hartzell, Monica, 1953-, et al. (författare)
  • Parents' perception of their first encounter with child and adolescent psychiatry
  • 2010
  • Ingår i: Contemporary family therapy. - : Springer. - 0892-2764 .- 1573-3335. ; 32:3, s. 273-289
  • Tidskriftsartikel (refereegranskat)abstract
    • Parents who came with their child to Child and Adolescent Psychiatry (CAP) for the first time were interviewed 1–2 weeks afterwards in the presence of the child and the therapists. In a grounded theory analysis they revealed uncertainty about their role in the first meeting as well as of future planning. What had been important to them were aspects like communication, sharing perspectives, and the reformulation of problems. 
  • Hartzell, Monica, 1953-, et al. (författare)
  • Therapists' Views of the First Meeting at Child and Adolescent Psychiatry
  • Annan publikation (övrigt vetenskapligt)abstract
    • Therapists’ influence on the therapeutic relationship is not much studied. In the first session in child and adolescent psychiatry (CAP) therapists are supposed to conduct assignments connected to the medical model. In psychotherapy the first meeting is regarded as having great impact on the continuation. Despite this, there are few studies on the issue. The aim was to learn more about the therapists’ perception of first meetings in CAP. Therapists were interviewed together with the families they had met. Reflectors helped the interviewer to hold on to the theme. The interviews were video-recorded. The data analysis was inspired by grounded theory. Two aspects appeared in the therapists’ descriptions, psychiatric and family psychotherapeutic ones. Psychiatric aspects included the demands from the organisation like making assessments and making families want to come back. In the meeting it converged with wishes from the family members: wanting to be in a dialogue with their therapists and negotiating the planning process. The therapists addressed that parents and children contributed to success in the meeting. Balancing between the psychiatric and the family psychotherapeutic aspects without questioning one’s own professional skills as CAP personnel seemed to be a challenge for the therapists.
  • Hartzell, Monica, 1953-, et al. (författare)
  • What children feel about their first encounter with child and adolescent psychiatry
  • 2009
  • Ingår i: Contemporary family therapy. - 0892-2764 .- 1573-3335. ; 31:3, s. 177-192
  • Tidskriftsartikel (refereegranskat)abstract
    • The first meeting in psychotherapeutic and psychosocial work, has a big impacton the continuation. It is a less explored research field. Children’s ‘‘voices’’ tend to come inthe back-ground in family therapy and other settings. In a project at CAP (Child andAdolescent Psychiatry) the children’s views were collected in interviews with parents andtherapists present. The grounded theory analysis process was used. The children addressedthe importance of the therapist’s actions and positions in helping them to be able tocommunicate and to be in a dialogue. To be accepted and allowed to express feelings wasimportant, and so was how the therapist managed to adjust to each person in the room andgive space for various perspectives.
  • Janols, Lars-Olof, 1943-, et al. (författare)
  • Central stimulants in the Treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents : A naturalistic study of the prescription in Sweden 1977-2007
  • 2009
  • Ingår i: Nordic Journal of Psychiatry. - 0803-9488 .- 1502-4725. ; 63:6, s. 508-516
  • Tidskriftsartikel (refereegranskat)abstract
    • Central   stimulants in the treatment of attention-deficit hyperactivity disorder   (ADHD) in children and adolescents. A naturalistic study of the   prescription in Sweden, 1977-2007. Nord J Psychiatry 2009; 63: 508-516.   Background: An increased prescription of central stimulants (CS) for   treatment of attention-deficit hyperactivity disorder (ADHD) in   children and adolescents has been reported in Sweden. Aims: To   follow-up the treatment with CS as concerns total as well as regional   differences in prescription rate. Efficacy and side-effects reported   and gender differences in prescription over time also have been   summarized. Methods: Data from the Swedish Medical Products Agency   (MPA) of individual licences, annual reports about patients on   individual or clinic licences from the MPA and sales statistics from   the National Pharmacy (Apoteket AB) have been used. Results: The number   of new licences and prescriptions increased dramatically from 1992 to   2007 and a change of preparations was seen. Great differences   (fivefold) between the 21 counties of Sweden were noticed. In the   follow-up reports to the MPA, a good/moderate treatment effect was   reported in 92% and adverse effects were reported in 4% leading to   discontinuation of medication in 46% of them. Abuse/misuse of the   preparation was suspected in 0.2% of the reports. A tendency of a   reduction of the proportion of boys to girls treated through individual   licences has been seen. Conclusions: The study, although observational,   supports good efficacy, limited adverse effects and a low degree of   misuse in clinical use of CS for children and adolescents with ADHD.
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