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Träfflista för sökning "WFRF:(Andreasson Håkan) srt2:(2010-2014)"

Sökning: WFRF:(Andreasson Håkan) > (2010-2014)

  • Resultat 1-10 av 28
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1.
  • Hall, Sara, et al. (författare)
  • Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders.
  • 2012
  • Ingår i: Archives of neurology. - 1538-3687. ; 69:11, s. 1445-52
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To assess the ability of 5 cerebrospinal fluid (CSF) biomarkers to differentiate between common dementia and parkinsonian disorders. Design: A cross-sectional, clinic-based study. Participants: Cerebrospinal fluid samples (N=453) were obtained from healthy individuals serving as controls and from patients with Parkinson disease (PD), PD with dementia (PDD), dementia with Lewy bodies (DLB), Alzheimer disease (AD), progressive supranuclear palsy (PSP), multiple system atrophy (MSA), or corticobasal degeneration (CBD). Setting: Neurology and memory disorder clinics. Main Outcome Measures: Cerebrospinal fluid biomarker levels in relation to clinical diagnosis. Results: Cerebrospinal fluid levels of alpha-synuclein were decreased in patients with PD, PDD, DLB, and MSA but increased in patients with AD. Cerebrospinal fluid levels of beta-amyloid 1-42 were decreased in DLB and even further decreased in AD. Cerebrospinal fluid levels of total tau and hyperphosphorylated tau were increased in AD. Multivariate analysis revealed that these biomarkers could differentiate AD from DLB and PDD with an area under the curve of 0.90, with alpha-synuclein and total tau contributing most to the model. Cerebrospinal fluid levels of neurofilament light chain were substantially increased in atypical parkinsonian disorders (ie, PSP, MSA, and CBD), and multivariate analysis revealed that the level of neurofilament light chain alone could differentiate PD from atypical parkinsonian disorders, with an area under the curve of 0.93. Conclusions: Ascertainment of the alpha-synuclein level in CSF somewhat improves the differential diagnosis of AD vs DLB and PDD when combined with established AD biomarkers. The level of neurofilament light chain alone may differentiate PD from atypical parkinsonian disorders.
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2.
  • Andreasson, Håkan, 1966- (författare)
  • Black hole formation from a complete past for the einstein–vlasov system
  • 2014
  • Ingår i: International conference on Relativity and Gravitation, 2012, Prague, Czech Republic, 25-29 June 2012. - 0930-8989 .- 1867-4941. - 978-3-319-06760-5 ; 157, s. 11-18
  • Konferensbidrag (refereegranskat)abstract
    • Anatural question in general relativity is to find initial data for the Einstein equations whose past evolution is regular and whose future evolution contains a black hole. In [1] initial data of this kind is constructed for the spherically symmetric Einstein–Vlasov system. One consequence of the result is that there exists a class of initial data for which the ratio of the Hawking mass (Formula presented) (r) and the area radius r is arbitrarily small everywhere, such that a black hole forms in the evolution. This result is analogous to the result [2] for a scalar field. Another consequence is that there exist black hole initial data such that the solutions exist for all Schwarzschild time t ∈ (−∞,∞). In the present article we review the results in [1].
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3.
  • Andreasson, Håkan, 1966- (författare)
  • Black Hole Formation from a Complete Regular Past for Collisionless Matter
  • 2012
  • Ingår i: Annales Henri Poincaré. - 1424-0637. ; 13:7, s. 1511-1536
  • Tidskriftsartikel (refereegranskat)abstract
    • Initial data for the spherically symmetric Einstein-Vlasov system is constructed whose past evolution is regular and whose future evolution contains a black hole. This is the first example of initial data with these properties for the Einstein-matter system with a "realistic" matter model. One consequence of the result is that there exists a class of initial data for which the ratio of the Hawking mass mIS= mIS (r) and the area radius r is arbitrarily small everywhere, such that a black hole forms in the evolution. This result is in a sense analogous to the result (Christodoulou Commun Pure Appl Math 44:339-373, 1991) for a scalar field. Another consequence is that there exist black hole initial data such that the solutions exist for all Schwarzschild time .
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4.
  • Andreasson, Håkan, 1966-, et al. (författare)
  • Bounds on M/R for charged objects with positive cosmological constant
  • 2012
  • Ingår i: Classical and Quantum Gravity. - 0264-9381. ; 29:9
  • Tidskriftsartikel (refereegranskat)abstract
    • We consider charged spherically symmetric static solutions of the Einstein-Maxwell equations with a positive cosmological constant Lambda. If r denotes the area radius, m(g) and q the gravitational mass and charge of a sphere with area radius r respectively, we find that for any solution which satisfies the condition p + 2p(perpendicular to) +/- = 0 and p(perpendicular to) are the radial and tangential pressures respectively, rho >= 0 is the energy density, and for which 0
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5.
  • Andréasson, Håkan, et al. (författare)
  • Cytoreductive surgery in pseudomyxoma peritonei-aspects of the learning curve
  • 2013
  • Ingår i: European Journal of Surgical Oncology. - 0748-7983 .- 1532-2157. ; 40:8, s. 930-936
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Cytoreductive surgery (CRS) plus perioperative intraperitoneal chemotherapy is a highly invasive treatment of peritoneal metastasis and requires many surgical procedures before mastering. The aim of this study was to estimate how many procedures are needed before stabilization can be seen in surgical outcome (R1 surgery, adverse events and bleeding) in patients with pseudomyxoma peritonei (PMP). Patients and methods: All 128 patients with PMP who were treated with CRS alone or CRS plus perioperative intraperitoneal chemotherapy between 2003 and 2008 at the Uppsala University Hospital, Uppsala, Sweden, were included. The learning curve was calculated using the partial least square (PLS) and cumulative sum control chart (CUSUM) graph. Two groups were formed based on the results of the learning curve. The learning curve plateau was considered the same as the stabilization in the CUSUM graph. Group I consisted of patients included during the learning period (n = 73) and Group 11 of patients treated after the learning period ended (n = 55). Comparisons between the groups were made on surgical outcome, survival and adverse events. Results: Stabilization was seen after 220 +/- 10 procedures. A higher occurrence of R1 surgery was seen in Group H (80%) compared to Group I (48%; P = 0.0002). Overall survival increased at four years after surgery in Group H compared to Group I (80% vs. 63%; P = 0.02). Conclusion: CRS plus perioperative intraperitoneal chemotherapy is a highly demanding procedure that requires more than 200 procedures before optimisation in surgical outcome is seen.
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6.
  • Andreasson, Håkan, 1966-, et al. (författare)
  • Existence of axially symmetric static solutions of the Einstein-Vlasov system
  • 2011
  • Ingår i: Commun. Math. Phys.. - 0010-3616. ; 308, s. 23-47
  • Tidskriftsartikel (refereegranskat)abstract
    • We prove the existence of static, asymptotically flat non-vacuum spacetimes with axial symmetry where the matter is modeled as a collisionless gas. The axially symmetric solutions of the resulting Einstein-Vlasov system are obtained via the implicit function theorem by perturbing off a suitable spherically symmetric steady state of the Vlasov-Poisson system.
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7.
  • Andreasson, Håkan, 1966-, et al. (författare)
  • Existence of axially symmetric static solutions of the Einstein-Vlasov system
  • 2011
  • Ingår i: Communications in Mathematical Physics. - 1432-0916 .- 0010-3616. ; 308:1, s. 23-47
  • Tidskriftsartikel (refereegranskat)abstract
    • We prove the existence of static, asymptotically flat non-vacuum spacetimes with axial symmetry where the matter is modeled as a collisionless gas. The axially symmetric solutions of the resulting Einstein-Vlasov system are obtained via the implicit function theorem by perturbing off a suitable spherically symmetric steady state of the Vlasov-Poisson system.
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8.
  • Andreasson, Håkan, 1966-, et al. (författare)
  • Formation of trapped surfaces for the spherically symmetric Einstein-Vlasov system
  • 2010
  • Rapport (övrigt vetenskapligt)abstract
    • We consider the spherically symmetric, asymptotically flat, nonvacuum Einstein equations, using as matter model a collisionless gas as described by the Vlasov equation. We find explicit conditions on the initial data which guarantee the formation of a trapped surface in the evolution which in particular implies that weak cosmic censorship holds for these data. We also analyze the evolution of solutions after a trapped surface has formed and we show that the event horizon is future complete. Furthermore we find that the apparent horizon andthe event horizon do not coincide. This behavior is analogous to what is found in certain Vaidya spacetimes. The analysis is carried out in Eddington-Finkelstein coordinates.
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9.
  • Andreasson, Håkan, 1966-, et al. (författare)
  • Formation of trapped surfaces for the spherically symmetric Einstein-Vlasov system
  • 2010
  • Ingår i: Journal of Hyperbolic Differential Equations. - 0219-8916. ; 7:4, s. 707-731
  • Tidskriftsartikel (refereegranskat)abstract
    • We consider the spherically symmetric, asymptotically flat, non-vacuum Einstein equations, using as matter model a collisionless gas as described by the Vlasov equation. We find explicit conditions on the initial data which guarantee the formation of a trapped surface in the evolution which in particular implies that weak cosmic censorship holds for these data. We also analyze the evolution of solutions after a trapped surface has formed and we show that the event horizon is future complete. Furthermore we find that the apparent horizon and the event horizon do not coincide. This behavior is analogous to what is found in certain Vaidya spacetimes. The analysis is carried out in Eddington-Finkelstein coordinates.
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10.
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  • Resultat 1-10 av 28
  • [1]23Nästa
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