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Sökning: WFRF:(Berglund Monica)

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1.
  • Rönn, Monika, et al. (författare)
  • Bisphenol A exposure increases liver fat in juvenile fructose-fed Fischer 344 rats
  • 2013
  • Ingår i: Toxicology. - 0300-483X. ; 303:1, s. 125-132
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND:Prenatal exposure to bisphenol A (BPA) has been shown to induce obesity in rodents. To evaluate if exposure also later in life could induce obesity or liver damage we investigated these hypothesises in an experimental rat model.METHODS: From five to fifteen weeks of age, female Fischer 344 rats were exposed to BPA via drinking water (0.025, 0.25 or 2.5mgBPA/L) containing 5% fructose. Two control groups were given either water or 5% fructose solution. Individual weight of the rats was determined once a week. At termination magnetic resonance imaging was used to assess adipose tissue amount and distribution, and liver fat content. After sacrifice the left perirenal fat pad and the liver were dissected and weighed. Apolipoprotein A-I in plasma was analyzed by western blot.RESULTS:No significant effects on body weight or the weight of the dissected fad pad were seen in rats exposed to BPA, and MRI showed no differences in total or visceral adipose tissue volumes between the groups. However, MRI showed that liver fat content was significantly higher in BPA-exposed rats than in fructose controls (p=0.04). BPA exposure also increased the apolipoprotein A-I levels in plasma (p<0.0001).CONCLUSION: We found no evidence that BPA exposure affects fat mass in juvenile fructose-fed rats. However, the finding that BPA in combination with fructose induced fat infiltration in the liver at dosages close to the current tolerable daily intake (TDI) might be of concern given the widespread use of this compound in our environment.
2.
  • Rönn, Monika, et al. (författare)
  • Quantification of total and visceral adipose tissue in fructose-fed rats using water-fat separated single echo MRI
  • 2013
  • Ingår i: Obesity. - 1930-7381. ; 21:9, s. E388-E395
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The aim of this study was to setup a rodent model for modest weight gain and an MRI-based quantification of body composition on a clinical 1.5 T MRI system for studies of obesity and environmental factors and their possible association. Design and Methods: Twenty-four 4-week-old female Fischer rats were divided into two groups: one exposed group (n=12) and one control group (n 12). The exposed group was given drinking water containing fructose (5% for 7 weeks, then 20% for 3 weeks). The control group was given tap water. Before sacrifice, whole body MRI was performed to determine volumes of total and visceral adipose tissue and lean tissue. MRI was performed using a clinical 1.5 T system and a chemical shift based technique for separation of water and fat signal from a rapid single echo acquisition. Fat signal fraction was used to separate adipose and lean tissue. Visceral adipose tissue volume was quantified using semiautomated segmentation. After sacrifice, a perirenal fat pad and the liver were dissected and weighed. Plasma proteins were analyzed by Western blot. Results: The weight gain was 5.2% greater in rats exposed to fructose than in controls (P=0.042). Total and visceral adipose tissue volumes were 5.2 cm(3) (P=0.017) and 3.1 cm(3) (P=0.019) greater, respectively, while lean tissue volumes did not differ. The level of triglycerides and apolipoprotein A-I was higher (P=0.034, P=0.005, respectively) in fructose-exposed rats.
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3.
  • Andersson, N., et al. (författare)
  • Amplitude modulation of light from various sources
  • 1994
  • Ingår i: Lighting Research and Technology. - Sage Publications. - 1477-1535. ; 26:3, s. 157-160
  • Tidskriftsartikel (refereegranskat)abstract
    • This work was done to obtain basic knowledge about various light sources and specially about light modulation, or flicker. The study showed that the modulation of light varied a lot between different ordinary light sources. In general the 100 Hz component in the flickering light dominated. For incandescent lights the modulation increased with decreasing power and was in the range 10-22%. Light from the tungsten-halogen lamps had 2-6% modulation. The most common light sources (single-colour fluorescent light) had a modulation of about 20%. Fluorescent tubes with better colour rendering (full-colour fluorescent and full-colour special fluorescent tubes) had a higher modulation, 30-40%, while light from high-frequency (HF) fluorescent tubes had a modulation of 0.9%. Light from conventional compact fluorescent tubes had a modulation degree of about 44%, and for HF compact fluorescent tubes it was 2-7%. Modulation of light from HF compact fluorescent tubes had a tendency to decrease with increasing tube size. The modulation of light from discharge lamps was in the range of 52% up to 100% and the curve form of the light from low pressure sodium vapour lamp (100% modulation) contained several high frequency components.
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4.
  • Berglund, Eva, et al. (författare)
  • Communicative skills in relation to gender, birth order, childcare and socioeconomic status in 18-month-old children
  • 2005
  • Ingår i: Scandinavian Journal of Psychology. - 0036-5564. ; 46:6, s. 485-491
  • Tidskriftsartikel (refereegranskat)abstract
    • Variation in communicative skills, defined as gestures, vocabulary comprehension and vocabulary production, was examined as a function of gender, birth order, childcare and socioeconomic status (SES) in 1,019 18-month-old children. The children were recruited at their regular check-up at a number of randomly selected Child Health Care centers in a Swedish county. The participation rate was 88%. The children were assessed by their mothers using a short version of the Swedish Early Communicative Development Inventories. The results demonstrate significant effects of gender and birth order on vocabulary comprehension and vocabulary production. Girls scored higher than boys and first-born children scored higher than later-born children. Type of childcare (family care, care at home and day-care centers) interacted with gender and birth order on vocabulary production and indicated that family care is not as advantageous as care at home or at day-care centers. SES had no effect on children's communicative skills at this age.
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9.
  • Berglund, Karin, et al. (författare)
  • Provoking identities : Entrepreneurship and emerging identity positions in rural development
  • 2016
  • Ingår i: Entrepreneurship and Regional Development. - Routledge. - 0898-5626. ; 28:1-2, s. 76-96
  • Tidskriftsartikel (refereegranskat)abstract
    • This article discusses entrepreneurship in a depleted community in transition. The purpose is to develop knowledge about how discourses are used in the positioning of identity in regional development. The concept positioning illustrates how identities are provoked, challenged, negotiated and moved into identity positions that break away from the idea of imitating successful and wealthy regions; instead, locality, place and history emerge as important resources from where local actors obtain agency and recognize new opportunities. Ethnographic data of a single case were collected over a six-year period between 2005 and 2010. The longitudinal nature of the study made it possible to incorporate how local stakeholders took on new identity positions, while handling their inspiration as well as their frustration. Results show how rural change was conditioned by discourses and how entrepreneurship challenged and reframed dominating structures through interaction between entrepreneurship and community. Four discourses, expressed as dichotomies available to people in this depleted community, illustrate the interactive process of positioning: change vs. traditions, rational vs. irrational, spectacular vs. mundane and individual vs. collective. The results support research emphasizing perspectives that acknowledge interaction between entrepreneurship and context as well as discursive aspects of regional development.
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