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Sökning: WFRF:(Johansson Anders W 1951 )

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  • Andersson, Lena, et al. (författare)
  • Small business promotion and intermediating as societal entrepreneurship
  • 2012
  • Ingår i: Societal Entrepreneurship : Positioning, Penetrating, Promoting. - Cheltenham : Edward Elgar Publishing. - 978-1-78100-632-0 ; s. 117-138
  • Bokkapitel (övrigt vetenskapligt)abstract
    • Most social ventures cross the boundaries between the private, the public and the non-profit/voluntary sectors, and this broad involvement of actors and intertwining of sectors makes the label 'societal' entrepreneurship more appropriate. Stating the importance of both the local and the broader societal context, the book reports close-up studies from a variety of social ventures. Generic themes include positioning societal entrepreneurship against other images of collective entrepreneurship, critically penetrating its assumptions and practices and proposing ways of promoting societal entrepreneurship more widely.
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  • Forslund, Anna-Lena, 1964-, et al. (författare)
  • Direct repeat-mediated deletion of a type IV pilin gene results in major virulence attenuation of Francisella tularensis
  • 2006
  • Ingår i: Molecular Microbiology. - Blackwell Publishing Ltd. - 0950-382X. ; 59:6, s. 1818-1830
  • Tidskriftsartikel (refereegranskat)abstract
    • Francisella tularensis, the causative agent of tularaemia, is a highly infectious and virulent intracellular pathogen. There are two main human pathogenic subspecies, Francisella tularensis ssp. tularensis (type A), and Francisella tularensis ssp. holarctica (type B). So far, knowledge regarding key virulence determinants is limited but it is clear that intracellular survival and multiplication is one major virulence strategy of Francisella. In addition, genome sequencing has revealed the presence of genes encoding type IV pili (Tfp). One genomic region encoding three proteins with signatures typical for type IV pilins contained two 120 bp direct repeats. Here we establish that repeat-mediated loss of one of the putative pilin genes in a type B strain results in severe virulence attenuation in mice infected by subcutaneous route. Complementation of the mutant by introduction of the pilin gene in cis resulted in complete restoration of virulence. The level of attenuation was similar to that of the live vaccine strain and this strain was also found to lack the pilin gene as result of a similar deletion event mediated by the direct repeats. Presence of the pilin had no major effect on the ability to interact, survive and multiply inside macrophage-like cell lines. Importantly, the pilin-negative strain was impaired in its ability to spread from the initial site of infection to the spleen. Our findings indicate that this putative pilin is critical for Francisella infections that occur via peripheral routes.
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  • Johannisson, Bengt, et al. (författare)
  • Avslutande reflektioner
  • 2012
  • Ingår i: Famileföretagande : affärer och känslor. - Stockholm : SNS förlag. - 978-91-86949-19-8 ; s. 355-366
  • Bokkapitel (övrigt vetenskapligt)
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  • Johansson, Anders W., 1951-, et al. (författare)
  • Bringing practice and theory together through entrepreneurial learning
  • 2014
  • Ingår i: Hawaii international conference on education : 2014 conference proceedings. - Honolulu : Hawaii International Conference on Education.
  • Konferensbidrag (refereegranskat)abstract
    • The paper is based upon experiences from a Swedish Business School of educating in the area of Entrepreneurship. Starting from traditional class room teaching, a specific pedagogical concept “entrepreneurial learning” emerged. The paper discusses how interaction with partner organizations and local communities can be used on bachelor and master level.
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  • Resultat 1-10 av 22
 
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