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- Jonsson, Pernilla Jonsson, 1967-
(författare)
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"Följ de omtänksamma husmödrarnas exempel" : livsmedelsannonsering i en svensk dagstidning, 1875-1965
- 2009
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Ingår i: Historisk Tidskrift (S). - 0345-469X. ; 2, s. 205-234
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Tidskriftsartikel (refereegranskat)abstract
- Handeln dominerade som annonsör under hela en studerade perioden. Märkesreklam i fabrikanters regi förekom redan 1875 och denna form av livsmedelannonsering var särskilt vanlig under 1920- och 1930-talen. Märkesvarorna var framför allt förpackade kolonialvaror samt nya processade varor där branschen präglades av oligopol och nya inbrytare. Fabrikanter, ofta utländska, var först med livsstilsannonsering. Under 1920- och 1930-talen befäste konsumentorienterad marknadsföring sin position i svensk dagstidningsreklam. Någonstans kring 1920 könades tilltalet i livsmedelsannonserna och riktades till framförallt kvinnor, definierade i en heterosexuell relation. Annonserna anspelade exempelvis på en önskan om en god hälsa eller att bli bekräftad som en lyckad hustru genom att tillfredställa man och barns önskningar. Men framförallt var det den goda husmoderns kunskap och förväntade önskan om att få hushållspengarna att räcka till som lyftes fram. Vid mitten av 1960-talet hade dock det suggestiva och normativa inslaget i livsmedelsannonserna minskat och varumärkesreklamen flyttats från dagstidningssidorna till veckotidningar och tidskrifter.
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- Eliasson, Pernilla, et al.
(författare)
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Hypoxia mediates low cell-cycle activity and increases the proportion of long-term reconstituting hematopoietic stem cells during in vitro culture
- 2010
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Ingår i: EXPERIMENTAL HEMATOLOGY. - 0301-472X. ; 38:4, s. 301-310
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Tidskriftsartikel (refereegranskat)abstract
- Objective. Recent evidence suggests that hematopoietic stem cells (HSCs) in the bone marrow (BM) are located in areas where the environment is hypoxic. Although previous studies have demonstrated positive effects by hypoxia, its role in HSC maintenance has not been fully elucidated, neither has the molecular mechanisms been delineated. Here, we have investigated the consequence of in vitro incubation of HSCs in hypoxia prior to transplantation and analyzed the role of hypoxia-inducible factor (HIF)-1 alpha. Materials and Methods. HSC and progenitor populations isolated from mouse BM were cultured in 20% or 1% O-2, and analyzed for effects on cell cycle, expression of cyclin-dependent kinase inhibitors genes, and reconstituting ability to lethally irradiated mice. The involvement of HIF-1 alpha was studied using methods of protein stabilization and gene silencing. Results. When long-term FLT3(-)CD34(-)Lin(-)Sca-1(+)c-Kit(+) (LSK) cells were cultured in hypoxia, cell numbers were significantly reduced in comparison to normoxia. This was due to a decrease in proliferation and more cells accumulating in G(0). Moreover, the proportion of HSCs with long-term engraftment potential was increased. Whereas expression of the cyclin-dependent kinase inhibitor genes p21(cip1), p27(Kip1), and p57(Kip2) increased in LSK cells by hypoxia, only p21(cip1) was upregulated in FLT3(-)CD34(-)LSK cells. We could demonstrate that expression of p27(KiP1) and p57(Kip2) was dependent of HIF-1 alpha. Surprisingly, overexpression of constitutively active HIF-1 alpha or treatment with the HIF stabilizer agent FG-4497 led to a reduction in HSC reconstituting ability. Conclusions. Our results imply that hypoxia, in part via HIF-1 alpha, maintains HSCs by decreasing proliferation and favoring quiescence.
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- Hedenrud, Tove, 1967-, et al.
(författare)
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Beliefs about medicines and adherence among Swedish migraineurs.
- 2007
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Ingår i: The 13th Congress of the International Headache Society, Stockholm, juni 2007..
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Konferensbidrag (refereegranskat)abstract
- Objective The aim was to analyze whether beliefs about medicines are associated with adherence to prophylactic medication among Swedish migraineurs. Methods A questionnaire was distributed consecutively to migraineurs attending a tertiary clinic. All participants were prescribed prophylactic medication. The questionnaire comprised e.g. background questions, beliefs about medicines (BMQ), and self-reported adherence (MARS). The General BMQ comprises three subparts: General Harm, General Overuse, and General Benefit. The specific part of the BMQ has two subparts: Specific Necessity and Specific Concerns. For the BMQ Specific, a necessity–concerns differential was calculated for each participant. A logistic regression analysis was performed to analyze the association between beliefs about medicines and adherence to prophylactic medication. Results Of the 175 participants, 15% were male and more than half of the participants were aged 45 years and over. Fifty percent had a university degree. Sixty-four percent were considered adherent. There was no significant difference in adherence between gender, age groups, or by educational level. Respondents with only compulsory school were less concerned about the long-term effects of medications and had a higher necessity–concern differential. In the logistic regression analysis, no variable was significantly associated with adherence. Conclusions The present study showed no association between beliefs about medication and adherence. We recommend that lack of adherence to migraine prophylactic drugs should be considered more often, looked for, and addressed in order to identify sufferers with an unnecessarily high migraine-associated disability. This assumes greater attention to the problem amongst both physicians and researchers in all countries.
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- Jonsson, Pernilla, et al.
(författare)
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Comparison and transfer : a fruitful approach to national history?
- 2007
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Ingår i: Scandinavian Journal of History. - 0346-8755. ; 32:3, s. 258-280
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this article is to discuss how a combined comparative and transnational approach can widen our understanding of historical change. By using examples from the first wave of the women's movement in Sweden and Canada we argue that exploring national differences, investigating differences in class and political culture and finally even tracing the transfer of resources and ideas could open up for new perspectives in gender history. Comparisons of women's organizing in different countries, but within the same international organizations, could help us to discern common structures that otherwise tend to be regarded as unique in one national context. In addition, such an approach can help to highlight specific national opportunities, cultures or strategies influencing the outcome of women's organizing.
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