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Träfflista för sökning "WFRF:(Tapper Michael) "

Sökning: WFRF:(Tapper Michael)

  • Resultat 1-10 av 441
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1.
  • Ghoussaini, Maya, et al. (författare)
  • Genome-wide association analysis identifies three new breast cancer susceptibility loci
  • 2012
  • Ingår i: Nature genetics. - 1546-1718. ; 44:3, s. 312-U120
  • Tidskriftsartikel (refereegranskat)abstract
    • Breast cancer is the most common cancer among women. To date, 22 common breast cancer susceptibility loci have been identified accounting for ~8% of the heritability of the disease. We attempted to replicate 72 promising associations from two independent genome-wide association studies (GWAS) in ~70,000 cases and ~68,000 controls from 41 case-control studies and 9 breast cancer GWAS. We identified three new breast cancer risk loci at 12p11 (rs10771399; P = 2.7 × 10−35), 12q24 (rs1292011; P = 4.3 × 10−19) and 21q21 (rs2823093; P = 1.1 × 10−12). rs10771399 was associated with similar relative risks for both estrogen receptor (ER)-negative and ER-positive breast cancer, whereas the other two loci were associated only with ER-positive disease. Two of the loci lie in regions that contain strong plausible candidate genes: PTHLH (12p11) has a crucial role in mammary gland development and the establishment of bone metastasis in breast cancer, and NRIP1 (21q21) encodes an ER cofactor and has a role in the regulation of breast cancer cell growth.
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2.
  • Tapper, Michael, et al. (författare)
  • Editorial
  • 2009
  • Ingår i: Fim International issue 38: Crime Film & TV. - Intellect Ltd.. - 2040-3801 .- 1651-6826. ; 7, s. 4-5
  • Bokkapitel (övrigt vetenskapligt)abstract
    • Editorial of Film International issue 38: Crime Film & TV
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3.
  • Tapper, Michael, et al. (författare)
  • Ledare: Alfred Hitchcock 100 år
  • 1999
  • Ingår i: Filmhäftet. - Filmhäftet. - 0345-3057. ; 27, s. 4-4
  • Bokkapitel (övrigt vetenskapligt)
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4.
  • Andersson, Lars Gustaf, et al. (författare)
  • Inledning: David Aquilon, Magisk cirkel
  • 2005
  • Ingår i: David Aquilon: Magisk cirkel. - Film International. - 91-974142-2-0 ; s. 1-8
  • Bokkapitel (övrigt vetenskapligt)abstract
    • Introduction to the edition of the unfinished doctoral dissertation "Magisk cirkel" by David Aquilon (1965 - 1999), focusing on the films of Ingmar Bergman and expecially "The Serpent's Egg" (1977).
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5.
  • Couch, Fergus J., et al. (författare)
  • Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
  • 2016
  • Ingår i: Nature Communications. - NATURE PUBLISHING GROUP. - 2041-1723. ; 7:11375, s. 1-13
  • Tidskriftsartikel (refereegranskat)abstract
    • Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 x 10(-8)) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative cases and 14,352 controls, combined with 7,333 ER-negative cases and 42,468 controls and 15,252 BRCA1 mutation carriers genotyped on the iCOGS array. We identify four previously unidentified loci including two loci at 13q22 near KLF5, a 2p23.2 locus near WDR43 and a 2q33 locus near PPIL3 that display genome-wide significant associations with ER-negative breast cancer. In addition, 19 known breast cancer risk loci have genome-wide significant associations and 40 had moderate associations (P<0.05) with ER-negative disease. Using functional and eQTL studies we implicate TRMT61B and WDR43 at 2p23.2 and PPIL3 at 2q33 in ER-negative breast cancer aetiology. All ER-negative loci combined account for similar to 11% of familial relative risk for ER-negative disease and may contribute to improved ER-negative and BRCA1 breast cancer risk prediction.
6.
  • Film International Issue 1
  • 2003
  • Ingår i: Film International. - Intellect Ltd.. - 1651-6826. ; 1:1
  • Annan publikation (övrigt vetenskapligt)abstract
    • Contents: Editorial (Michael Tapper), Ingmar Bergman's Writings and Films (Maaret Koskinen), The Perfect Money Machine(s): George Lucas and Steven Spielberg (Jon Lewis), Genre Films and Cultural Myth (Barry Keith Grant), Nobody's Perfect: Billy Wilder and Postwar American Cinema (William Rothman), Peter Watkins: Culloden x 2 (Nicholas J Cull/John R Cook). Reviews: books, films.
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7.
  • Film International Issue 11
  • 2004
  • Ingår i: Film International. - Intellect Ltd.. - 1651-6826. ; 2:5
  • Annan publikation (övrigt vetenskapligt)abstract
    • Contents: Larry Cohen: Film Crazy - An Interview (Patrick McGilligan), Fucking Monsters: Post-Apocalyptic Desire in Tim Roths The War Zone (Charles Jason Lee), Only (Dis)Connect and never Relaxez-Vous Or, I Can't Sleep: Claire Denis - Cinema of Transgressiom 2:2 (Robin Wood), I Bollywood an Imitation of Hollywood?: Western Media Influence on The Indian Movie Industry (Soo Ye Hoo), Shakespeare in Translation (Daniel Gronsky). Reviews: books, dvds, films
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8.
  • Film International Issue 12
  • 2004
  • Ingår i: Film International. - Intellect Ltd.. - 1651-6826. ; 2:6
  • Annan publikation (övrigt vetenskapligt)abstract
    • Contents: Planet Osaka: Independent Japanese Film (Johannes Schönherr), Interview with Walter Hill: Last Man Standing (Patrick McGilligan), False Criticism: Cinema and the Conservative Critique of Bourgeois Society (Christopher Sharrett), Hollywood/Taiwan: Connections, Countercurrents and Ang Lee's Hulk (Gina Marchetti), Louise Brooks: The Martyrdom of Lulu (Dan Callahan). Reviews: film festivals.
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9.
  • Film International Issue 14
  • 2005
  • Ingår i: Film International. - Intellect Ltd.. - 1651-6826. ; 3:2
  • Annan publikation (övrigt vetenskapligt)abstract
    • Contents: Editorial (Michael Tapper), Errol Morris' Forms of Control (Ira Jaffe), Masao Adachi: Portrait of a Radical in Cinema and Politics (Johannes Schönherr), Paranoia Pictures Presents... (Michael Coyne), The Heroism of Disobediance and Deceit: Where Is the Friend's Home? (Robin Wood). Reviews: books, dvds, film festivals.
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10.
  • Film International Issue 15
  • 2005
  • Ingår i: Film International. - Intellect Ltd.. - 1651-6826. ; 3:3
  • Annan publikation (övrigt vetenskapligt)abstract
    • Contents: Ingmar Bergman as "Ingmar Bergman" (Jan Holmberg), THX 1138: A Portrait of the Artist as an Angry Young Man (Andrew Gordon), Shamans, Sex Beasts and Abuse: Mother-Son Relationships in Popular and Cult Cinema (Charles Jason lee), Neo-Splatter: Bride of Chucky and the Horror of Heteronormative (Judith Halberstam), The Irrational Enlargement of Queen Kong (IQ Hunter), Pictures of the Lands of Violent Death: Kiyotaka Tsurisaki Interviewed (Johannes Schönherr). reviews: dvds, books.
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