SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Wennerberg Ann 1955 ) ;lar1:(cth)"

Sökning: WFRF:(Wennerberg Ann 1955 ) > Chalmers tekniska högskola

  • Resultat 1-10 av 21
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  • Alenezi, Ali, et al. (författare)
  • Characteristics of 2 Different Commercially Available Implants with or without Nanotopography
  • 2013
  • Ingår i: International Journal of Dentistry. - 1687-8728. ; 2013:Art. no. 769768
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to assess histologically and histomorphometrically the early bone forming properties after 3 weeks for 2 commercially available implants, one supposedly possessing nanotopography and one without, in a rabbit femur model. Twenty-four implants divided equally into 2 groups were utilized in this study. The first group (P-I MICRO+NANO) was a titanium oxide (TiO2) microblasted and noble gas ion bombarded surface while the second group (Ospol) was anodic oxidized surface with calcium and phosphate incorporation. The implants were placed in the rabbit femur unicortically and were allowed to heal for 3 weeks. After euthanasia, the samples were subjected to histologic sectioning and bone-implant contact and bone area were evaluated histomorphometrically under an optical microscope. The histomorphometric evaluation presented that the P-I MICRO+NANO implants demonstrated significantly higher new bone formation as compared to the Ospol implants. Within the limitations of this study, the results suggested that nanostructures presented significantly higher bone formation after 3 weeks in vivo, and the effect of chemistry was limited, which is indicative that nanotopography is effective at early healing periods.
4.
  •  
5.
  • Bougas, Kostas, et al. (författare)
  • In vitro Evaluation of Calcium Phosphate Precipitation on Possibly Bioactive Titanium Surfaces in the Presence of Laminin.
  • 2011
  • Ingår i: Journal of Oral & Maxillofacial Research. - 2029-283X. ; 2:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives: The aim of the present study was to evaluate calcium phosphate precipitation and the amount of precipitated protein on three potentially bioactive surfaces when adding laminin in simulated body fluid. Material and Methods: Blasted titanium discs were prepared by three different techniques claimed to provide bioactivity: alkali and heat treatment (AH), anodic oxidation (AO) or hydroxyapatite coating (HA). A blasted surface incubated in laminin-containing simulated body fuid served as a positive control (B) while a blasted surface incubated in non laminin-containing simulated body fuid served as a negative control (B-). The immersion time was 1 hour, 24 hours, 72 hours and 1 week. Surface topography was investigated by interferometry and morphology by Scanning Electron Microscopy (SEM). Analysis of the precipitated calcium and phosphorous was performed by Energy Dispersive X-ray Spectroscopy (EDX) and the adsorbed laminin was quantified by iodine (125I) labeling. Results: SEM demonstrated that all specimens except for the negative control were totally covered with calcium phosphate (CaP) after 1 week. EDX revealed that B- demonstrated lower sum of Ca and P levels compared to the other groups after 1 week. Iodine labeling demonstrated that laminin precipitated in a similar manner on the possibly bioactive surfaces as on the positive control surface. Conclusions: Our results indicate that laminin precipitates equally on all tested titanium surfaces and may function as a nucleation center thus locally elevating the calcium concentration. Nevertheless further studies are required to clarify the role of laminin in the interaction of biomaterials with the host bone tissue.
6.
  •  
7.
  • Cecchinato, Francesca, et al. (författare)
  • In vitro evaluation of human fetal osteoblast response to magnesium loaded mesoporous TiO2 coating.
  • 2013
  • Ingår i: Journal of biomedical materials research. Part A. - 1552-4965. ; 102:11, s. 3862-3871
  • Tidskriftsartikel (refereegranskat)abstract
    • This work aimed to evaluate the in vitro response of Transfected Human Foetal Osteoblast (hFOB) cultured on a magnesium-loaded mesoporous TiO2 coating. The application of mesoporous films on titanium implant surfaces has shown very promising potential to enhance osseointegration. This type of coating has the ability to act as a framework to sustain bioactive agents and different drugs. Magnesium is the element that, after calcium, is the most frequently used to dope titanium implant surfaces, since it is crucial for protein formation, growth factor expression, and aids for bone mineral deposition on implant surfaces. Mesoporous TiO2 films with an average pore-size of 6 nm were produced by the evaporation-induced self-assembly method (EISA) and deposited onto titanium discs. Magnesium loading was performed by soaking the mesoporous TiO2discs in a magnesium chloride solution. Surface characterization was con- ducted by SEM, XPS, optical interferometry, and AFM. Magnesium release profile was assessed at different time points using a Magnesium Detection kit. Cell morphology and spreading were observed with SEM. The cytoskeletal organization was stained with TRITC-conjugated Phalloidin and cell viability was evaluated through a mitochondrial colorimetric (MTT) assay. Furthermore, gene expression of bone markers and cell mineralization were analyzed by real time RT-PCR and alizarin-red staining, respectively. The surface chemical analysis by XPS revealed the successful adsorption of magnesium to the mesoporous coating. The AFM measurements revealed the presence of a nanostructured surface roughness. Osteoblasts viability and adhesion as well as the gene expression were unaffected by the addition of magnesium possibly due to its rapid burst release, however, were enhanced by the 3D nanostructure of the TiO2l ayer.
  •  
8.
  • Franke Stenport, Victoria, 1970-, et al. (författare)
  • Precipitation of calcium phosphate in the presence of albumin on titanium implants with four different possibly bioactive surface preparations. An in vitro study
  • 2008
  • Ingår i: Journal of Materials Science: Materials in Medicine. - 0957-4530. ; 19:12, s. 3497-3505
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of the present study was to compare the nucleating behaviour on four types of bioactive surfaces by using the simulated body fluid (SBF) model with the presence albumin. Titanium discs were blasted (B) and then prepared by alkali and heat treatment (AH), anodic oxidation (AO), fluoridation (F), or hydroxyapatite coating (HA). The discs were immersed in SBF with 4.5 mg/ml albumin for 3 days, 1, 2, 3 and 4 weeks and analysed with scanning electron microscopy/energy dispersive X-ray analysis (SEM/EDX) and X-ray photoelectron spectroscopy (XPS). Topographic surface characterisation was performed with a contact stylus profilometer. The results demonstrated that the bioactive surfaces initiated an enhanced calcium phosphate (CaP) formation and a more rapid increase of protein content was present on the bioactive surfaces compared to the blasted control surface. The observation was present on all bioactive surfaces. The fact that there was a difference between the bioactive surfaces and the blasted control surface with respect to precipitation of CaP and protein content on the surfaces support the fact that there may be biochemical advantages in vivo by using a bioactive surface.
  •  
9.
  • Göransson, Anna, 1970-, et al. (författare)
  • An in vitro comparison of possibly bioactive titanium implant surfaces.
  • 2009
  • Ingår i: Journal of Biomedical Materials Research Part A. - 1552-4965. ; 88:4, s. 1037-1047
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of the study was to compare Ca and P formation (CaP) and subsequent bone cell response of a blasted and four different possibly bioactive commercially pure (cp) titanium surfaces; 1. Fluoride etched (Fluoride), 2. Alkali-heat treated (AH), 3. Magnesium ion incorporated anodized (TiMgO), and 4. Nano HA coated and heat treated (nano HA) in vitro. Furthermore, to evaluate the significance of the SBF formed CaP coat on bone cell response. The surfaces were characterized by Optical Interferometry, Scanning Electron Microscopy (SEM) and X-ray Photoelectron Spectroscopy (XPS). CaP formation was evaluated after 12, 24 and 72 h in simulated body fluid (SBF). Primary human mandibular osteoblast-like cells were cultured on the various surfaces subjected to SBF for 72 h. Cellular attachment, differentiation (osteocalcin) and protein production (TGF-beta(1)) was evaluated after 3 h and 10 days respectively. Despite different morphological appearances, the roughness of the differently modified surfaces was similar. The possibly bioactive surfaces gave rise to an earlier CaP formation than the blasted surface, however, after 72 h the blasted surface demonstrated increased CaP formation compared to the possibly bioactive surfaces. Subsequent bone cell attachment was correlated to neither surface roughness nor the amount of formed CaP after SBF treatment. In contrast, osteocalcin and TGF-beta(1) production were largely correlated to the amount of CaP formed on the surfaces. However, bone response (cell attachment, osteocalcin and TGF-F production) on the blasted controls were similar or increased compared to the SBF treated fluoridated, AH and TiMgO surface.
  •  
10.
  • Hayashi, Mariko, et al. (författare)
  • In vitro characterization and osteoblast responses to nanostructured photocatalytic TiO2 coated surfaces
  • 2012
  • Ingår i: Acta Biomaterialia. - Elsevier. - 1742-7061. ; 8:6, s. 2411-2416
  • Tidskriftsartikel (refereegranskat)abstract
    • The aims of the study were to characterize a nanostructured photoactive titanium dioxide (TiO(2)) coating and to compare the cellular response of human osteoblasts before and after ultraviolet (UV) irradiation of the coating. A specific nanostructured TiO(2) powder (Degussa P-25), which consists of approximately 80% anatase and 20% rutile, was spin-coated onto commercially pure titanium discs, and was heat-treated thereafter. After topographical, chemical and photocatalytic property characterizations, human osteoblasts were cultured on the coated discs before and after UV irradiation. Cell morphology was evaluated by scanning electron microscopy (SEM), and cell viability was analysed by 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium bromide (MTT) assay. From the contact angle analysis, the wettability significantly improved after UV irradiation. The cultured cells were flattened with numerous elongated lammellipodia; however, no morphological differences were indicated between -UV and +UV surfaces. The MTT assay analysis showed that -UV surface presented significantly higher viability compared to the +UV surface except for one cell population group at 3h where there were no differences. The nanostructured photoactive TiO(2) surface improved its hydrophilicity by UV irradiation, however no enhancing effect in cell response was confirmed at the time tested compared to the non-irradiated surface.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 21
Åtkomst
fritt online (3)
Typ av publikation
tidskriftsartikel (21)
Typ av innehåll
refereegranskat (21)
Författare/redaktör
Wennerberg, Ann, 195 ... (21)
Andersson, Martin, 1 ... (15)
Jimbo, Ryo, 1979-, (7)
Franke Stenport, Vic ... (7)
Currie, Fredrik, 197 ... (6)
Albrektsson, Tomas, ... (5)
visa fler...
Arvidsson, Anna, 197 ... (5)
Kjellin, Per, 1972-, (5)
Svanborg, Lory Melin ... (5)
Sul, Young-Taeg, 196 ... (4)
Meirelles, Luiz, 197 ... (4)
Hayashi, Mariko (3)
Johansson, Carina B. ... (2)
Mustafa, K. (2)
Kjellin, Per (2)
Mustafa, Kamal (2)
Bougas, Kostas (2)
Sawase, Takashi (2)
Schwartz-Filho, Humb ... (2)
Melin Svanborg, Lory ... (2)
Martinelli, Anna, 19 ... (1)
Tengvall, Pentti, (1)
Petronis, Sarunas, 1 ... (1)
Andersson, Martin (1)
Karlsson, Johan (1)
Skarnemark, Gunnar, ... (1)
Lindh, Liselott (1)
Alenezi, Ali (1)
Naito, Yoshihito (1)
Chrcanovic, Bruno R. (1)
Allard, Stefan, 1968 ... (1)
Coelho, Paulo G (1)
Kjellin, P (1)
Sotres, Javier (1)
Currie, Fredrik (1)
Halvarsson, Mats, 19 ... (1)
Hayashi, M. (1)
Karlsson, Johan, 198 ... (1)
Hoffman, Maria (1)
Xue, Ying (1)
Södervall, Ulf, 1954 ... (1)
Xue, Y, (1)
Schwartz-Filho, H.O. ... (1)
Currie, F. (1)
Vandeweghe, Stefan (1)
Jeong, Yongsoo (1)
Cecchinato, Francesc ... (1)
He, Wenxiao, 1985-, (1)
Peltola, Timo, (1)
Fathali, Hoda Mashad ... (1)
visa färre...
Lärosäte
Göteborgs universitet (15)
Malmö högskola (13)
RISE (1)
Språk
Engelska (21)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (21)
Teknik (3)
Naturvetenskap (1)

År

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy