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Sökning: WFRF:(Wierzbicka Aneta)

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  • Bekö, Gabriel, et al. (författare)
  • Ultrafine particles: Exposure and source apportionment in 56 Danish homes.
  • 2013
  • Ingår i: Abstract of the 2013 Conference of the International Society of Environmental Epidemiology (ISEE), the International Society of Exposure Science (ISES), and the International Society of Indoor Air Quality and Climate (ISIAQ). - Environ Health Perspect.. ; No. 4059, ID: P-2-08-23
  • Annan publikation (refereegranskat)
  • Bekö, Gabriel, et al. (författare)
  • Ultrafine Particles: Exposure and Source Apportionment in 56 Danish Homes
  • 2013
  • Ingår i: Environmental Science & Technology. - AMER CHEMICAL SOC. - 0013-936X. ; 47:18, s. 10240-10248
  • Tidskriftsartikel (refereegranskat)abstract
    • ABSTRACT: Particle number (PN) concentrations (10−300 nm in size) were continuously measured over a period of ∼45 h in 56 residences of nonsmokers in Copenhagen, Denmark. The highest concentrations were measured when occupants were present and awake (geometric mean, GM: 22.3 × 103 cm−3), the lowest when the homes were vacant (GM: 6.1 × 103 cm−3) or the occupants were asleep (GM: 5.1 × 103 cm−3). Diary entries regarding occupancy and particle related activities were used to identify source events and apportion the daily integrated exposure among sources. Source events clearly resulted in increased PN concentrations and decreased average particle diameter. For a given event, elevated particle concentrations persisted for several hours after the emission of fresh particles ceased. The residential daily integrated PN exposure in the 56 homes ranged between 37 × 103 and 6.0 × 106 particles per cm3·h/day (GM: 3.3 × 105 cm−3·h/day). On average, ∼90% of this exposure occurred outside of the period from midnight to 6 a.m. Source events, especially candle burning, cooking, toasting, and unknown activities, were responsible on average for ∼65% of the residential integrated exposure (51% without the unknown activities). Candle burning occurred in half of the homes where, on average, it was responsible for almost 60% of the integrated exposure.
  • Hagerman, Inger, et al. (författare)
  • Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study
  • 2014
  • Ingår i: Atmospheric Environment. - Elsevier. - 1352-2310. ; 88, s. 165-171
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in nano-sized particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups. Aim of study: The aim was to evaluate the impact of nano-sized indoor air particles on HRV for healthy and adult females. Methods: All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene + ozone reactions or filtered air in a double-blind cross over design. Twenty-two healthy females were investigated during 10 min periods at different exposures and the reactivity in high frequency (HF) spectral band of HRV were computed. Results: Heart rate was unchanged from baseline values in all groups during all experimental settings. HF power of HRV tended to increase during exposure to particles from burning candle while particles from terpene + ozone reactions tended to decrease HF power. Conclusions: Exposure to nano-sized particles of burning candles or terpene + ozone reactions results in different patterns of heart rate variability, with signs of altered autonomic cardiovascular control. Practical implications: This study indicates that the HRV method may be used for information on physiological responses of exposure to different nano-sized particles and contribute to the understanding of mechanisms behind health effects of particle exposures. (C) 2014 The Authors. Published by Elsevier Ltd.
  • Isaxon, Christina, et al. (författare)
  • A Novel System for Source Characterization and Controlled Human Exposure to Nanoparticle Aggregates Generated During Gas–Metal Arc Welding
  • 2013
  • Ingår i: Aerosol Science and Technology. - Taylor and Francis. - 0278-6826. ; 47:1, s. 52-59
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instrumentation, consisting of a tapered element oscillating microbalance, a scanning mobility particle sizer, and a sampler for electron microscopy and particle-induced X-ray emission analysis was connected to the stainless steel chamber. The feasibility of the system for human exposure studies was evaluated by exposing 31 human volunteers, in groups of three, to a test aerosol containing 1 mg/m(3) welding fumes and to conditioned, filtered air. The results show that an aerosol that accurately represents dilute welding fume exposures that occur in workplaces can be produced in a controlled manner, and that the experimental setup can be used for 6 h, double-blind, exposures of human subjects. Particle mass concentration levels could be varied from <5 mu g/m(3) to more than 1000 mu g/m(3). Fumes from metal active gas welding showed a unimodal size distribution with a mean mobility diameter of 160 nm, transmission electron microscopy showed aggregates with a clearly nanosized structure.
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