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Sökning: WFRF:(Wilson Mark 1954 )

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  • Artigas Soler, María, et al. (författare)
  • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
  • 2011
  • Ingår i: Nature genetics. - 1546-1718. ; 43:11, s. 1082-90
  • Tidskriftsartikel (refereegranskat)abstract
    • Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 second and the ratio of forced expiratory volume in 1 second to forced vital capacity in 48,201 individuals of European ancestry with follow up of the top associations in up to an additional 46,411 individuals. We identified new regions showing association (combined P < 5 × 10(-8)) with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2. Identification of these 16 new loci may provide insight into the molecular mechanisms regulating pulmonary function and into molecular targets for future therapy to alleviate reduced lung function.
  • Kilpeläinen, Tuomas O, et al. (författare)
  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
  • 2011
  • Ingår i: Nature genetics. - 1546-1718. ; 43:8, s. 753
  • Tidskriftsartikel (refereegranskat)abstract
    • Genome-wide association studies have identified 32 loci influencing body mass index, but this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-analyzed associations between similar to 2.5 million SNPs and body fat percentage from 36,626 individuals and followed up the 14 most significant (P &lt; 10(-6)) independent loci in 39,576 individuals. We confirmed a previously established adiposity locus in FTO (P = 3 x 10(-26)) and identified two new loci associated with body fat percentage, one near IRS1 (P = 4 x 10(-11)) and one near SPRY2 (P = 3 x 10(-8)). Both loci contain genes with potential links to adipocyte physiology. Notably, the body-fat-decreasing allele near IRS1 is associated with decreased IRS1 expression and with an impaired metabolic profile, including an increased visceral to subcutaneous fat ratio, insulin resistance, dyslipidemia, risk of diabetes and coronary artery disease and decreased adiponectin levels. Our findings provide new insights into adiposity and insulin resistance.
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • between you and me
  • 2011
  • Ingår i: Animal Influence, Interactive Futures ' 11, 17th to 19th November 2011, Vancouver, Canada.
  • Konferensbidrag (refereegranskat)abstract
    • between you and me This presentation focuses on the exhibition by Snæbjörnsdóttir/Wilson, entitled “between you and me”. The project centres on the representations and intrinsic value of things and calls into question the myriad bases upon which we construct such representations. Snæbjörnsdóttir/Wilson have for some time in their work examined specific relationships between human and non-human animals – in “nanoq: flat out and bluesome” the polar bear, in “Big Mouth” the Tasmanian Tiger, in “(a)fly” urban pets etc. “between you and me” examines a contemporary set of relationships between humans and seals, with its particular focus on the coastal areas of Iceland where humans and seals, with its particular focus on the coastal areas of Iceland where interaction of one sort or another has been customary for many centuries. In the Kalmar Art Museum, the installation was interspersed throughout the entire building – on the ground floor, the library, the upper stairwell and the main gallery on the top floor. In this upper space, the artists placed their key video work, “the naming of things”, in direct dialogue with selected works from the collection at Kalmar including drawings, prints, paintings, photographs and textiles, all of which in one way or another represent animals. Our colonization of the building in this way, its implications for the audience, together with our staging of a public seminar event held during the exhibition are all discussed during this presentation. In addition, short video extracts will be screened. Because most representations are constructed to perform some agenda of our own – in the case of animals, to entertain, to inform, to provide food, to remember, to stand for all others of the species, to symbolize human behavioural characteristics etc – in this process, the animal itself is occluded – eclipsed by its avatar or likeness, which is always a simplification and therefore must accordingly signify a loss. Snæbjörnsdóttir/Wilson’s work challenges the anthropocentric systems of convenience that sanction a daily acceptance of such loss and in an attempt to address such historical and contemporary imbalance, posits the alternative idea of “parities in meeting”.
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • between you, nanoq and me
  • 2011
  • Ingår i: Cultures of Preservation, Animal Skin and Colonial Practice, 12th - 14th of May 2011, Natural History Museum, London.
  • Konferensbidrag (refereegranskat)
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Listrannsóknir og eigin verk
  • 2011
  • Ingår i: Bil Beggja: Safnið sem vettvangur lista og lærdóms, 15th October 2011, Hafnarborg, Iceland.
  • Konferensbidrag (refereegranskat)
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Uncertainty in the City
  • 2011
  • Ingår i: People, Places, Stories. 28-30th Sept. 2011, Linnaeus University, Kalmar.
  • Konferensbidrag (refereegranskat)abstract
    • Abstract Uncertainty in the City: Pets, Pests and Prey For millennia, humans have been making divisions between themselves and other animals. By building settlements, towns and cities, they created a refuge and a physical division separating themselves from wild animals. The artists Bryndís Snæbjörnsdóttir and Mark Wilson explored these divisions through their art project Uncertainty in the City. In this project they travelled with a mobile radio station interviewing people about their relationships to non-human animals. The result a series of stories located in the ever-shifting margins of tolerance, gathering anecdotes and stories of human/animal cohabitation, encroachment and mutually beneficial partnerships. This paper discusses their art project and some of the stories recorded.
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Uncertainty in the City: Pets, Pests and Prey
  • 2010
  • Ingår i: Uncertainty in the City: Pets, Pests and Prey, 21st Sept. to 27th of November 2010, Storey Gallery, Lancaster, UK.
  • Konstnärligt arbete (övrigt vetenskapligt)abstract
    • An exhibition in which the artists Snæbjörnsdóttir/Wilson explore our complex feelings towards our ‘animal others’. In 2007 Storey Gallery commissioned the artist team Snæbjörnsdóttir/Wilson to develop a project investigating the various and complex relationships between human and non-human animals in shared and contested spaces. Working primarily in the city of Lancaster and the surrounding area, with a variety of individuals, businesses and organisations, the artists burrowed around the ever-shifting margins of tolerance, gathering anecdotes and stories of human/animal cohabitation, encroachment and symbiotic partnerships. In addition, they toured around the UK with a mobile radio unit, visiting people’s homes, country fairs, and town centres, documenting the multiplicity of people’s feelings towards animals-in-proximity. The conversations were recorded and aired live on Radio Animal, an online radio station created by Snæbjörnsdóttir/Wilson, dedicated to their discourse around human/animal relations. For millennia, humans have been making divisions between themselves and other animals. By building settlements, towns and cities, they created shelter and insulation from wild animals. However, animals have always been attracted to concentrations of human population because of the opportunities these provide for habitat and food. For some humans, the presence of these creatures – pigeons, starlings, rats, mice, foxes, and all manner of insects - constitutes a threat, a kind of leakage. It highlights the fragility of our insulation from the ‘wild’, its unpredictability, and the seeming chaos of ‘nature’. The exhibition Uncertainty in the City: Pests, Pets, and Prey explores this animal infringement through the use of sound, sculpture, text, video, and photography. It builds a picture of human ambivalence towards animals – of tolerance and intolerance, of fear and loathing, of affection, conflict, and admiration - and at the same time it explores more broadly our own duplicity in relation to ideas of the ‘other’.
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Uncertainty in the City: Pets, Pests and Prey
  • 2011
  • Bok (övrigt vetenskapligt)abstract
    • Snæbjörnsdóttir/Wilson: Uncertainty in the City is a result of a research project in which Bryndis Snæbjörnsdóttir and Mark Wilson investigated the margins of tolerance in the fraught relationship between humans and other animals. During their research they observed ambivalence and contradictory vested interests in relation to a wide range of creatures. Most significant is the mixture of responses, the paradoxical nature of human attitudes towards agents of the ‘wild’, and the implicit cohesion-in-tension of the human/nature paradigm. Uncertainty in the City is a guidebook that looks at the human response to the other, to the animals that surround us. The form of the book refers to the genre of field guides and thus underlines the research-based nature of the artistic practice of Snæbjörnsdòttir/Wilson. With contributions by Erica Fudge, Chris Wilbert, Peter Lurz, Rikke Hansen and Suzy Jones.
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Vanishing Point.
  • 2011
  • Ingår i: The GIBCA Speak Easy, 7th September 2011, House of Win Win, Gothenburg Biennial 2011..
  • Konferensbidrag (övrigt vetenskapligt)
  • Snæbjørnsdóttir, Bryndis, 1955-, et al. (författare)
  • Vanishing Point: Where Species Meet
  • 2011
  • Ingår i: Artistic Seminar, 8th December 2011, Faculty of Fine, Applied and Performing Art, Gothenburg University.
  • Konferensbidrag (övrigt vetenskapligt)abstract
    • Abstract: Vanishing Point: Where Species Meet Vanishing Point: Where Species Meet is the title of Snæbjörnsdóttir/Wilson’s most recent artwork, which was part of the Gothenburg Biennial 2011. The title, which references Donna Haraway’s book When Species Meet, pinpoints significant ambiguities in meetings between human and animal. The focus of this artwork is the attempt by the artist to share a meal with members of another species, namely seagulls, on camera. The three-screen video work sets out the conditions for a meeting but does not fetishize or document the act of species coming together. The talk will explore the thinking behind this artwork and the processes of its making. It will question the ambition of recording an equal meeting between human and animal, at least on camera and in the context of contemporary art, whilst avoiding either being sensationalist or prompting readings of domestication. It proposes that despite the impossibility of a visual exposition of this meeting, a meeting has nevertheless occurred which as a consequence, provides the basis for considering the nature and the possibilities of such a connection.
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