| 1. |
- Bauer, M., et al.
(författare)
-
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
- 2021
-
Ingår i: International Journal of Bipolar Disorders. - : Springer Science and Business Media LLC. - 2194-7511. ; 9:1
-
Tidskriftsartikel (refereegranskat)abstract
- Background Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. Methods Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun's electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). Results This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. Conclusion A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed.
|
|
| 2. |
- Bauer, M., et al.
(författare)
-
Association between polarity of first episode and solar insolation in bipolar I disorder
- 2022
-
Ingår i: Journal of Psychosomatic Research. - : Elsevier BV. - 0022-3999 .- 1879-1360. ; 160
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar insolation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P ≤ 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.
|
|
| 3. |
- Bauer, M., et al.
(författare)
-
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
- 2023
-
Ingår i: International Journal of Bipolar Disorders. - 2194-7511. ; 11:1
-
Tidskriftsartikel (refereegranskat)abstract
- BackgroundSunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample.MethodsData for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P <= 0.001.ResultsThe 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger.ConclusionUVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
|
|
| 4. |
- Bauer, M., et al.
(författare)
-
Solar insolation in springtime influences age of onset of bipolar I disorder
- 2017
-
Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 136:6, s. 571-582
-
Forskningsöversikt (refereegranskat)abstract
- Objective: To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. Method: Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth-cohort, family history, polarity of first episode and country physician density. Results: There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset. This effect was reduced in those without a family history of mood disorders and with a first episode of mania rather than depression. The maximum monthly increase occurred in springtime. The youngest birth-cohort had the youngest age of onset. All prior relationships were confirmed using both the entire sample, and only the youngest birth-cohort (all estimated coefficients P < 0.001). Conclusion: A large increase in springtime solar insolation may impact the onset of bipolar disorder, especially with a family history of mood disorders. Recent societal changes that affect light exposure (LED lighting, mobile devices backlit with LEDs) may influence adaptability to a springtime circadian challenge.
|
|
| 5. |
- Wild, J. A., et al.
(författare)
-
Midnight sector observations of auroral omega bands
- 2011
-
Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 116, s. A00I30-
-
Tidskriftsartikel (refereegranskat)abstract
- We present observations of auroral omega bands on 28 September 2009. Although generally associated with the substorm recovery phase and typically observed in the morning sector, the features presented here occurred just after expansion phase onset and were observed in the midnight sector, dawnward of the onset region. An all-sky imager located in northeastern Iceland revealed that the omega bands were similar to 150 x 200 km in size and propagated eastward at similar to 0.4 km s(-1) while a colocated ground magnetometer recorded the simultaneous occurrence of Ps6 pulsations. Although somewhat smaller and slower moving than the majority of previously reported omega bands, the observed structures are clear examples of this phenomenon, albeit in an atypical location and unusually early in the substorm cycle. The THEMIS C probe provided detailed measurements of the upstream interplanetary environment, while the Cluster satellites were located in the tail plasma sheet conjugate to the ground-based all-sky imager. The Cluster satellites observed bursts of 0.1-3 keV electrons moving parallel to the magnetic field toward the Northern Hemisphere auroral ionosphere; these bursts were associated with increased levels of field-aligned Poynting flux. The in situ measurements are consistent with electron acceleration via shear Alfven waves in the plasma sheet similar to 8 R-E tailward of the Earth. Although a one-to-one association between auroral and magnetospheric features was not found, our observations suggest that Alfven waves in the plasma sheet are responsible for field-aligned currents that cause Ps6 pulsations and auroral brightening in the ionosphere. Our findings agree with the conclusions of earlier studies that auroral omega bands have a source mechanism in the midtail plasma sheet.
|
|
| 6. |
- Andersson, L., et al.
(författare)
-
New Features of Electron Phase Space Holes Observed by the THEMIS Mission
- 2009
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:22, s. 225004-
-
Tidskriftsartikel (refereegranskat)abstract
- Observations of electron phase-space holes (EHs) in Earth's plasma sheet by the THEMIS satellites include the first detection of a magnetic perturbation (delta B-parallel to) parallel to the ambient magnetic field (B-0). EHs with a detectable delta B-parallel to have several distinguishing features including large electric field amplitudes, a magnetic perturbation perpendicular to B-0, high speeds (similar to 0.3c) along B-0, and sizes along B-0 of tens of Debye lengths. These EHs have a significant center potential (Phi similar to k(B)T(e)/e), suggesting strongly nonlinear behavior nearby such as double layers or magnetic reconnection.
|
|
| 7. |
- Bauer, Michael, et al.
(författare)
-
Association between solar insolation and a history of suicide attempts in bipolar I disorder.
- 2019
-
Ingår i: Journal of psychiatric research. - : Elsevier BV. - 1879-1379 .- 0022-3956. ; 113, s. 1-9
-
Tidskriftsartikel (refereegranskat)abstract
- In many international studies, rates of completed suicide and suicide attempts have a seasonal pattern that peaks in spring or summer. This exploratory study investigated the association between solar insolation and a history of suicide attempt in patients with bipolar I disorder. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area on Earth. Data were collected previously from 5536 patients with bipolar I disorder at 50 collection sites in 32 countries at a wide range of latitudes in both hemispheres. Suicide related data were available for 3365 patients from 310 onset locations in 51 countries. 1047 (31.1%) had a history of suicide attempt. There was a significant inverse association between a history of suicide attempt and the ratio of mean winter solar insolation/mean summer solar insolation. This ratio is smallest near the poles where the winter insolation is very small compared to the summer insolation. This ratio is largest near the equator where there is relatively little variation in the insolation over the year. Other variables in the model that were positively associated with suicide attempt were being female, a history of alcohol or substance abuse, and being in a younger birth cohort. Living in a country with a state-sponsored religion decreased the association. (All estimated coefficients p < 0.01). In summary, living in locations with large changes in solar insolation between winter and summer may be associated with increased suicide attempts in patients with bipolar disorder. Further investigation of the impacts of solar insolation on the course of bipolar disorder is needed.
|
|
| 8. |
- Ergun, R. E., et al.
(författare)
-
Observations of Double Layers in Earth's Plasma Sheet
- 2009
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:15, s. 155002-
-
Tidskriftsartikel (refereegranskat)abstract
- We report the first direct observations of parallel electric fields (E-parallel to) carried by double layers (DLs) in the plasma sheet of Earth's magnetosphere. The DL observations, made by the THEMIS spacecraft, have E-parallel to signals that are analogous to those reported in the auroral region. DLs are observed during bursty bulk flow events, in the current sheet, and in plasma sheet boundary layer, all during periods of strong magnetic fluctuations. These observations imply that DLs are a universal process and that strongly nonlinear and kinetic behavior is intrinsic to Earth's plasma sheet.
|
|
| 9. |
- Eriksson, S., et al.
(författare)
-
Magnetic island formation between large-scale flow vortices at an undulating postnoon magnetopause for northward interplanetary magnetic field
- 2009
-
Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 114:2, s. A00C17-
-
Tidskriftsartikel (refereegranskat)abstract
- Time History of Events and Macroscale Interactions during Substorms multispacecraft observations are presented for a similar to 2-h-long postnoon magnetopause event on 8 June 2007 that for the first time indicate that the trailing (sunward) edges of Kelvin-Helmholtz (KH) waves are commonly related to small-scale < 0.56 R-E magnetic islands or flux transfer events (FTE) during the growth phase of these surface waves. The FTEs typically show a characteristic bipolar B-N structure with enhanced total pressure at their center. Most of the small-scale FTEs are not related to any major plasma acceleration. TH-A observations of one small FTE at a transition from the low-latitude boundary layer (LLBL) into a magnetosheath plasma depletion layer were reconstructed using separate techniques that together confirm the presence of a magnetic island within the LLBL adjacent to the magnetopause. The island was associated with a small plasma vortex and both features appeared between two large-scale (similar to 1 R-E long and 2000 km wide) plasma vortices. We propose that the observed magnetic islands may have been generated from a time-varying reconnection process in a low ion plasma beta (beta(i) < 0.2) and low 8.3 degrees field shear environment at the sunward edge of the growing KH waves where the local magnetopause current sheet may be compressed by the converging flow of the large-scale plasma vortices as suggested by numerical simulations of the KH instability.
|
|
| 10. |
- Johansson, T., et al.
(författare)
-
Observation of an inner magnetosphere electric field associated with a BBF-like flow and PBIs
- 2009
-
Ingår i: Annales Geophysicae. - : Copernicus GmbH. - 0992-7689 .- 1432-0576. ; 27:4, s. 1489-1500
-
Tidskriftsartikel (refereegranskat)abstract
- Themis E observed a perpendicular (to the magnetic field) electric field associated with an Earthward plasma flow at XGSM=-9.6 R-E on 11 January 2008. The electric field observation resembles Cluster observations closer to Earth in the auroral region. The fast plasma flow shared some characteristics with bursty bulk flows (BBFs) but did not meet the usual criteria in maximum velocity and duration to qualify as one. Themis C observed the same flow further downtail but Themis D, separated by only 1 R-E in azimuthal direction from Themis E, did not. At the time of the electric field and ion flow event, the all-sky imager and ground-based magnetometer at Rankin Inlet observed Poleward Boundary Intensifications (PBIs) and a negative bay signature. None of the other Themis ground-based observatories recorded any significant auroral or magnetic field activity, indicating that this was a localized activity. The joint Themis in situ and ground-based observations suggest that the two observations are related. This indicates that auroral electric fields can extend to regions much farther out than previously seen in Cluster observations.
|
|
