Search: WFRF:(Azizi E)
> (1997-1999) >
Obliteration of a p...
Obliteration of a posttraumatic spinal cord cyst with solid human embryonic spinal cord grafts : first clinical attempt.
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- Falci, S (author)
- Department of Neurosurgery, Craig Hospital, Denver, Colorado
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- Holtz, A (author)
- Uppsala universitet,Institutionen för neurovetenskap
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- Akesson, E (author)
- Karolinska Institutet
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- Azizi, M (author)
- Uppsala universitet,Institutionen för neurovetenskap
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- Ertzgaard, Per (author)
- Uppsala universitet,Linköpings universitet,Rehabiliteringsmedicin,Medicinska fakulteten,Institutionen för neurovetenskap
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- Hultling, C (author)
- Karolinska Institutet
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- Kjaeldgaard, A (author)
- Department of Clinical Science, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden
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- Levi, Richard (author)
- department of Clinical Neuroscience and Family Medicine, Karolinska Institute, Stockholm, Sweden,Spinalis
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- Ringden, O (author)
- Karolinska Institutet
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- Westgren, M (author)
- Karolinska Institutet
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- Lammertse, D (author)
- department of Physical Medicine and Rehabilitation, Craig Hospital, Denver, Colorado
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- Seiger, A (author)
- Karolinska Institutet,Spinalis
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Akesson, M (author)
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- Hultling, A (author)
- Spinalis
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(creator_code:org_t)
- Mary Ann Liebert Inc, 1997
- 1997
- English.
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In: Journal of Neurotrauma. - : Mary Ann Liebert Inc. - 0897-7151 .- 1557-9042. ; 14, s. 875-
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https://doi.org/10.1...
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Abstract
Subject headings
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- Cystic lesions of the spinal cord (syringomyelia) may occur after spinal cord injury. Posttraumatic syringomyelia may result in a myelopathy causing symptoms of sensory and motor loss, as well as worsening spasticity, pain, hyperhidrosis, and autonomic dysreflexia. Shunting of the cyst cavity along with untethering of the scarred spinal cord is widely accepted as the treatment of choice. However, the long-term stabilization of the progressive myelopathy caused by a posttraumatic cyst is suboptimal because of arachnoidal rescarring, shunt tube blockage, and cyst reexpansion. A new neurosurgical strategy to overcome the complication of cyst reexpansion was designed. Experimental studies have shown the successful use of embryonic spinal cord grafts, including human grafts, to obliterate induced spinal cord cavities in rats. The authors report the first use of solid human embryonic spinal cord grafts to successfully obliterate 6 cm of a large cyst cavity in a patient becoming myelopathic from a posttraumatic cyst. The grafts are well visualized by MRI to the 7-month postoperative follow-up and cyst obliteration is seen in the region where the grafts were placed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- syringomyelia; spinal cord injury; cyst; embryonic transplant; regeneration; tethering
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Falci, S
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Holtz, A
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Akesson, E
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Azizi, M
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Ertzgaard, Per
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Hultling, C
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show more...
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Kjaeldgaard, A
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Levi, Richard
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Ringden, O
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Westgren, M
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Lammertse, D
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Seiger, A
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Akesson, M
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Hultling, A
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
- Articles in the publication
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Journal of Neuro ...
- J Neurotrauma
- By the university
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Linköping University
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Umeå University
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Karolinska Institutet
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Uppsala University