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Sökning: WFRF:(Bäckman Lars) > (2000-2004)

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1.
  • Maitland, Scott B, et al. (författare)
  • Selective sex differences in declarative memory.
  • 2004
  • Ingår i: Mem Cognit. - : Springer Science and Business Media LLC. - 0090-502X .- 1532-5946. ; 32:7, s. 1160-9
  • Tidskriftsartikel (refereegranskat)abstract
    • Sex invariance of a six-factor, higher order model of declarative memory (two second-order factors: episodic and semantic memory; and four first-order factors: recall, recognition, fluency, and knowledge) was established for 1,796 participants (35-85 years). Metric invariance of first- and second-order factor loadings across sex was demonstrated. At the second-order level, a female advantage was observed for both episodic and semantic memory. At the first-order level, sex differences in episodic memory were apparent for both recall and recognition, whereas the differences in semantic memory were driven by a female superiority in fluency. Additional tests of sex differences in three age groups (35-50, 55-65, and 70-85 years of age) indicated that the female superiority in declarative memory diminished with advancing age. The factor-specific sex differences are discussed in relation to sex differences in hippocampal function.
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2.
  • Nilsson, Lars-Göran, et al. (författare)
  • Betula : a prospective cohort study on memory, health and aging
  • 2004
  • Ingår i: Aging, Neuropsychology and Cognition. - Hove : Psychology Press. - 1382-5585 .- 1744-4128. ; 11:2-3, s. 134-148
  • Tidskriftsartikel (refereegranskat)abstract
    • This article describes the Betula Study with respect to objectives, design, participants, and assessment instruments for health and cognition. Three waves of data collection have been completed in 5-year intervals since 1988-1990. A fourth wave started in 2003 and will be completed in 2005. An overview of Betula research is presented under the headings of memory and cognition and cognitive neuroscience. Health-related issues and sex differences as well as comparisons between cross-sectional and longitudinal studies are discussed in the first section. The influence of different genes and of some brain abnormalities for memory functioning in adulthood and old age constitute main topics in the second section. New data are presented on the association between blood pressure and dementia. We demonstrated that a demented group of participants had higher levels of systolic blood pressure and pulse pressure than non-dementia controls 10 years before diagnosis. The new fourth wave of data collection will, in addition to enriching the Betula database, permit revisiting and reanalyzing the existing data from new perspectives.
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3.
  • Nordling Nilson, Linda, 1947, et al. (författare)
  • Dose-related cognitive deficits among floor layers with previous heavy exposure to solvents.
  • 2003
  • Ingår i: Archives of environmental health. - 0003-9896. ; 58:4, s. 208-17
  • Tidskriftsartikel (refereegranskat)abstract
    • The authors used tests of attention and memory, which are sensitive to the influence of aging, to explore possible adverse effects on cognitive functioning following past heavy exposure to solvent-based glues, with special reference to dose-effect relationships and interactions with the aging process. The study included 41 floor layers and 40 carpenters (referents) who participated in a longitudinal follow-up assessment. The authors assessed cognitive functioning with the following tests: trail-making, color words, and word recall. Higher cumulative exposure was associated with poorer test performance that was related to concept shifting, episodic memory, and speed of congruent and incongruent color naming. The magnitude of the decrements in memory tasks was equivalent to about 20 yr of age-related decline. Dose-effect relationships were seen mainly for contact adhesives, and there was partial evidence for an interaction between exposure and aging.
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4.
  • Nyberg, Lars, et al. (författare)
  • Cognitive aging : A view from brain imaging
  • 2004
  • Ingår i: New frontiers in cognitive aging. - : Oxford University Press, Oxford. - 0 19 852569 9 ; , s. 135-159
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • The contributions in this volume, and numerous other journal articles and chapters, provide unequivocal evidence that cognitive functions decline across the adult lifespan Importantly, though, some cognitive functions are more affected than others For example, in recent work from the Betula project (Nilsson eta!, 1997), we contrasted episodic and semantic long term memory (Nyberg eta!, 2003) It was found that episodic memory performance deteriorated gradually from middle age through young-old age to old-old age By contrast, semantic memory performance increased from middle-age to young-old age, and the old-old participants performed at a level comparable to the middle aged (Figure 7 la) Furthermore, within the domam of episodic memory, increasing age was associated with a greater reduction of pei form ance on measures of recall compared to measures of recognition (Figure 7 ib) These results provide evidence that episodic long-term memory is more age-sensitive than semantic long-term memory, and that recall is more age-sensitive than recognition. These age-related long-term memory changes can be related to patterns of data in working-memory tasks (Gick, Crajic, and Morris, 1988) Working-memory tasks differ with regard to their demand on executive processing and it has been found that age differences are small when the executive demands are low, and substantial wlten such demands are high (see Morris, Gick and Craik, 1988). Many cognitive tasks require working memory functions to a smaller or greater extent, and it has been shown that working memory capacity accounts for a considerable portion of the variance in long-term memory tasks (Hultsch, I-Iertzog, and Dixon, 1990; Park eta!., 1996). Relatedly, the relationship between age and episodic memory has been found to be mediated by proficiency of executive functioning (Troyer, Graves, and Cullum, 1994).
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6.
  • Derwinger, Anna, et al. (författare)
  • Remembering Numbers in Old Age : Mnemonic Training Versus Self-Generated Strategy Training
  • 2003
  • Ingår i: Aging, Neuropsychology and Cognition. - : Routledge. - 1382-5585 .- 1744-4128. ; 10:3, s. 202-214
  • Tidskriftsartikel (refereegranskat)abstract
    • The effectiveness of two memory training programs designed to enhance four-digit number recall was examined in 90 healthy older adults. One group received instruction and training in the number-consonant mnemonic, whereas another group was instructed to adopt their own encoding and retrieval strategies to enhance number recall. Also, a control group receiving no training between testing occasions was included. The criterion task was administered according to the Buschke selective reminding procedure. Posttest performance was evaluated with and without cognitive support for remembering (i.e., verbal cues). Under unsupported conditions, the mnemonic group improved number recall following training and the selfgenerated strategy group showed a tendency in the same direction. When support was provided, group differences in favor of the two training groups increased. In addition, no training-related gains were observed in two verbal transfer tasks. The relatively similar patterns of gains in the two intervention groups were discussed in terms of advantages and disadvantages in the two training regimens balancing each other.
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7.
  • Falk, Lars, et al. (författare)
  • Genotyping of Chlamydia trachomatis would improve contact tracing
  • 2003
  • Ingår i: Sexually Transmitted Diseases. - : Ovid Technologies (Wolters Kluwer Health). - 0148-5717 .- 1537-4521. ; 30:3, s. 205-210
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The reported number of genital Chlamydia trachomatis infections has increased 15% annually since 1997 in Sweden. Inaccurate partner notification might be one reason.Goal: The goals were to determine if genotyping of C trachomatis would improve partner notification and to study the duration of infection.Study Design: Sexual networks were constructed. C trachomatis isolates from 231 individuals attending the Örebro STD clinic during 1 year were typed by sequencing of the omp1 gene.Results: All individuals were traced and diagnoses were established in 30 of 161 networks. More than one genotype was seen in seven networks. The mean duration of C trachomatis infection in each network was calculated to be 23 weeks.Conclusion: Genotyping could be a useful tool in partner notification when there are discrepant or uncommon genotypes. Limited clinic catchment areas create information difficulties that obstruct accurate contact tracing.
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8.
  • Forsberg, Anna, 1969, et al. (författare)
  • Experiencing liver transplantation: a phenomenological approach.
  • 2000
  • Ingår i: Journal of advanced nursing. - 0309-2402. ; 32:2, s. 327-34
  • Tidskriftsartikel (refereegranskat)abstract
    • In order to promote health, nurses and other health care professionals need to discover and articulate the meaning that is implicit in experiencing life after liver transplantation. From such an understanding, appropriate nursing interventions can be based. The aim of this study was to investigate the subjective experiences of the meaning of having a liver transplant, 1 year after the transplantation. After approval from the ethics committee at Goteborg University, 12 patients, nine women and three men, were interviewed. The study sample was chosen strategically to represent common diagnoses preceding liver transplantation. A phenomenological approach was chosen for the study. Analyses of the interviews were based on a modified version of a phenomenological method by Karlsson. Seven categories emerged: facing the inevitable; recapturing the body; emotional chaos; leaving the experts; family and friends; the threat of graft rejection; and honouring the donor. Having undergone a liver transplant meant living in a paradoxical situation. Knowing that you survived, it was a struggle to regain physical strength under great emotional stress. The recipients had to self-administer life-long medication, recognize symptoms indicating a potential problem and monitor for the possibility of graft rejection. Social support was essential for recovery. Meeting others with the same experience helped liver-transplanted patients to deal with their identity crises as well as undergo a transformation from being utterly unique to a survivor among others. The clinical implications from this study are that interventions, such as patient education, and social and mental support, are important tools to optimize both self-care capacity and the ability to maintain a healthy perception of identity after having a liver transplant at least up to 12 months post-transplant.
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9.
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10.
  • Forsberg, Anna, 1969, et al. (författare)
  • Liver transplant recipients' ability to cope during the first 12 months after transplantation--a prospective study.
  • 2002
  • Ingår i: Scandinavian journal of caring sciences. - 0283-9318 .- 1471-6712. ; 16:4, s. 345-52
  • Tidskriftsartikel (refereegranskat)abstract
    • Little is known about the coping style and coping strategies among liver transplant recipients. The aim of this study was to evaluate the change in the sense of coherence and coping strategies among liver transplant recipients before and during the first year after liver transplantation. The aim was also to study whether or not there was any relationship between the sense of coherence and the coping strategies. Thirty-five patients met the inclusion criteria. Twenty-six-patients gave their verbal consent to participate in this longitudinal study and 21 patients (80%) completed the follow-up study. The Sense of Coherence scale (SOC) was used for investigation of coping style. The Jalowiec Coping Scale (JCS-40) was used to assess general coping behaviour. The Ethics Committee gave approval to perform this study. The group was heterogeneous regarding the change in the sense of coherence with pronounced individual changes in meaningfulness during the first 3 months and in comprehensibility 6-12 months after liver transplantation. The group showed a homogeneous pattern of change in coping strategies. Confrontational coping strategy was commonly used during the period. A relationship was found between comprehensibility and palliative coping. This prospective study indicated that coping style, assessed by the SOC scale, changed primarily at an individual level during the first year after liver transplantation while changes in coping strategies, according to JSC-40, were in common for the group. The usual coping strategy during the first posttransplant year was confrontational coping.
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