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- Ahlberg, Rickard, 1970-, et al.
(författare)
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Auricular acupuncture for substance use : a randomized controlled trial of effects on anxiety, sleep, drug use and use of addiction treatment services
- 2016
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Ingår i: Substance Abuse Treatment, Prevention, and Policy. - London, United Kingdom : BioMed Central. - 1747-597X. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: A common alternative treatment for substance abuse is auricular acupuncture. The aim of the study was to evaluate the short and long-term effect of auricular acupuncture on anxiety, sleep, drug use and addiction treatment utilization in adults with substance abuse.Method: Of the patients included, 280 adults with substance abuse and psychiatric comorbidity, 80 were randomly assigned to auricular acupuncture according to the NADA protocol, 80 to auricular acupuncture according to a local protocol (LP), and 120 to relaxation (controls). The primary outcomes anxiety (Beck Anxiety Inventory; BAI) and insomnia (Insomnia Severity Index; ISI) were measured at baseline and at follow-ups 5 weeks and 3 months after the baseline assessment. Secondary outcomes were drug use and addiction service utilization. Complete datasets regarding BAI/ISI were obtained from 37/34 subjects in the NADA group, 28/28 in the LP group and 36/35 controls. Data were analyzed using Chi-square, Analysis of Variance, Kruskal Wallis, Repeated Measures Analysis of Variance, Eta square (η(2)), and Wilcoxon Signed Ranks tests.Results: Participants in NADA, LP and control group improved significantly on the ISI and BAI. There was no significant difference in change over time between the three groups in any of the primary (effect size: BAI, η(2) = 0.03, ISI, η(2) = 0.05) or secondary outcomes. Neither of the two acupuncture treatments resulted in differences in sleep, anxiety or drug use from the control group at 5 weeks or 3 months.Conclusion: No evidence was found that acupuncture as delivered in this study is more effective than relaxation for problems with anxiety, sleep or substance use or in reducing the need for further addiction treatment in patients with substance use problems and comorbid psychiatric disorders. The substantial attrition at follow-up is a main limitation of the study.Trial registration: Clinical Trials NCT02604706 (retrospectively registered).
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| 2. |
- Sagerfors, Marcus, MD, PhD, 1977-, et al.
(författare)
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Patient-Perceived Outcome After Total Wrist Arthroplasty : A Single-Center Study of 223 Cases
- 2016
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Ingår i: Hand. - : Sage Publications. - 1558-9447 .- 1558-9455. ; 11:1_suppl, s. 2S-2S
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: Total wrist arthroplasty (TWA) is an established surgical treatment for wrist arthritis. The aim of the investigation is to report patient-perceived outcome measures after TWA operated at a single referral center in Sweden.Methods: In a cohort study with prospective collection of data, we evaluated 193 consecutive patients with a TWA (223 wrists) preoperatively, 1 and 5 years postoperatively. The wrists were implanted between 2002 and 2014. Outcome measures studied were range of motion (ROM), visual analogue scale (VAS) pain scores, hand grip strength, and patient-related outcome measures. Secondary outcome measures included implant survivorship, which was estimated using the Kaplan-Meier method, and radiographic loosening 5 years postoperatively.Results: VAS pain scores and patient-related outcome measures improved significantly for all TWAs. Improved hand grip strength was noted for all TWAs except Universal 2. ROM improved somewhat, especially for the Biax and Maestro TWAs. Cumulative implant survival after 5 years was 99% for Remotion, 95% for Maestro, and 84% for Biax. Radiographic loosening was present in 26% of the Biax cases, 18% of the Remotion cases, and 2% of the Maestro cases.Conclusions: All TWA designs in this study offer a high level of patient satisfaction. The design of the implant may affect patient-perceived outcome 5 years postoperatively. Good mid to long-term results can be achieved in patients undergoing TWA.
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