| 1. |
- von Euler, G., et al.
(författare)
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Coactivation of dopamine D1 and D2 receptors increases the affinity of cholecystokinin-8 receptors in membranes from post-mortem human caudate-putamen
- 1992
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Ingår i: Brain Research. - Amsterdam, Netherlands : Elsevier. - 0006-8993 .- 1872-6240. ; 584:1-2, s. 157-162
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Tidskriftsartikel (refereegranskat)abstract
- The effects of dopamine in vitro were investigated on the binding sites for cholecystokinin-8 (sulphated, CCK-8) and neurotensin in membrane preparations of the caudate-putamen and nucleus accumbens of post-mortem human brains. Dopamine reduced the IC50 value of competition curves with CCK-8 for [125I]CCK-8 binding in membranes from the caudate-putamen, but not the nucleus accumbens, with a maximal decrease of -25 +/- 9% at 300 nM of dopamine. This decrease could be antagonized by 100 nM of SCH 23390 or 100 nM of raclopride. Kinetic analysis of [125I]CCK-8 binding showed a decrease in the first order dissociation rate constant and in the kinetic Kd (-22 +/- 6% and -24 +/- 6%, respectively) at 300 nM of dopamine, without any significant effect on the apparent or actual association rate constant. Competition curves with neurotensin versus [125I]neurotensin were not affected by dopamine (10-1000 nM) in membranes from the caudate-putamen or the nucleus accumbens. These results suggest that dopamine, by synergistic stimulation of both D1 and D2 receptors, selectively increases the affinity of CCK-8 receptors in the human caudate-putamen, by a selective inhibition of ligand dissociation. This increase may reflect a positive feed-back mechanism, further enhancing the modulatory effects of CCK-8 on dopamine neurotransmission.
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| 2. |
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| 3. |
- Duarte, L.G.S., et al.
(författare)
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Invertible point transformations, Painlevé analysis and anharmonic oscillators
- 1990
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Ingår i: Journal of Physics A. - : IOP Publishing. - 0305-4470 .- 1361-6447. ; 23, s. 1457-1463
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Tidskriftsartikel (refereegranskat)abstract
- The techniques of an invertible point transformation and the Painleve analysis can be used to construct integrable ordinary differential equations. The authors compare both techniques for anharmonic oscillators.
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| 4. |
- Euler, Norbert, et al.
(författare)
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Invertible point transformations, Painlevé test, and the second Painlevé transcendent
- 1991
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Ingår i: International journal of theoretical physics. - 0020-7748 .- 1572-9575. ; 30:9, s. 1267-1271
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Tidskriftsartikel (refereegranskat)abstract
- The techniques of invertible point transformations and the Painlevé analysis can be used to construct integrable ordinary differential equations. We compare both techniques for the second Painlevé transcendent.
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| 5. |
- Steeb, Willi-Hans, et al.
(författare)
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Painlevé test and energy level motion
- 1990
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Ingår i: International journal of theoretical physics. - 0020-7748 .- 1572-9575. ; 29:6, s. 637-642
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Tidskriftsartikel (refereegranskat)
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