↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Freedman Neal D) srt2:(2012)"

Sökning: WFRF:(Freedman Neal D) > (2012)

Resultat 1-2 av 2

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Lim, Stephen S, et al. (författare) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. 2012 Ingår i: Lancet. - 1474-547X. ; 380:9859, s. 2224-60 Tidskriftsartikel (refereegranskat)abstract Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No complete revision of global disease burden caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed changes in burden attributable to risk factors over time.
2.	Jacobs, Kevin B, et al. (författare) Detectable clonal mosaicism and its relationship to aging and cancer. 2012 Ingår i: Nature Genetics. - New York : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 44:6, s. 651-658 Tidskriftsartikel (refereegranskat)abstract In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples. We observed mosaic abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of >2 Mb in size in autosomes of 517 individuals (0.89%), with abnormal cell proportions of between 7% and 95%. In cancer-free individuals, frequency increased with age, from 0.23% under 50 years to 1.91% between 75 and 79 years (P = 4.8 × 10(-8)). Mosaic abnormalities were more frequent in individuals with solid tumors (0.97% versus 0.74% in cancer-free individuals; odds ratio (OR) = 1.25; P = 0.016), with stronger association with cases who had DNA collected before diagnosis or treatment (OR = 1.45; P = 0.0005). Detectable mosaicism was also more common in individuals for whom DNA was collected at least 1 year before diagnosis with leukemia compared to cancer-free individuals (OR = 35.4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases.

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-2 av 2

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (2)

Typ av innehåll: refereegranskat (2)

Författare/redaktör: Tjønneland, Anne (1); Boutron-Ruault, Mari ... (1); Krogh, Vittorio (1); Khaw, Kay-Tee (1); Romieu, Isabelle (1); Riboli, Elio (1); visa fler...; Petzold, Max, 1973 (1); Brunekreef, Bert (1); Wolk, Alicja (1); Henderson, Brian E (1); Haiman, Christopher ... (1); Berndt, Sonja I (1); Chanock, Stephen J (1); Gapstur, Susan M (1); Stevens, Victoria L (1); Albanes, Demetrius (1); Giles, Graham G (1); Kogevinas, Manolis (1); Sapkota, Amir (1); Johansen, Christoffe ... (1); Feychting, Maria (1); Farzadfar, Farshad (1); Jonas, Jost B. (1); Khang, Young-Ho (1); Lopez, Alan D. (1); Lozano, Rafael (1); Malekzadeh, Reza (1); Micha, Renata (1); Mozaffarian, Dariush (1); Naghavi, Mohsen (1); Vos, Theo (1); Murray, Christopher ... (1); Lim, Stephen S. (1); Mensah, George A. (1); Salomon, Joshua A. (1); Andersson, Ulrika (1); Gakidou, Emmanuela (1); Ahlbom, Anders (1); Gallinger, Steven (1); Visvanathan, Kala (1); White, Emily (1); Peters, Ulrike (1); Severi, Gianluca (1); Jiao, Li (1); Jenab, Mazda (1); Bueno-de-Mesquita, H ... (1); Trichopoulos, Dimitr ... (1); Canzian, Federico (1); Hallmans, Göran (1); Andrulis, Irene L. (1); visa färre...

Lärosäte: Göteborgs universitet (1); Umeå universitet (1); Uppsala universitet (1); Karolinska Institutet (1)

Språk: Engelska (2)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (2)

År: 2012 (2)Ta bort avgränsningen

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy