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1.	Gudmundsson, Julius, et al. (author) Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. 2008 In: Nat Genet. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 40:3, s. 281-3 Journal article (peer-reviewed)
2.	Ordeig, Olga, et al. (author) On-Chip Electric Field Driven Electrochemical Detection Using a Poly(dimethylsiloxane) Microchannel with Gold Microband Electrodes 2008 In: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 80:10, s. 3622-3632 Journal article (peer-reviewed)abstract An external electric field driven in-channel detection technique for on-chip electrochemical detection in micro fabricated devices is described based on a microfluidic system containing an array of 20 microband electrodes. It is shown that an external electric field induces a potential difference between two gold microband electrodes in a poly(dimethylsiloxane) (PDMS) microchannel, and that this enables the electrochemical detection of electroactive species such as ascorbic acid and Fe(CN)64−. The results, which are supported by simulations of the behavior of the microband electrodes in the microfluidic system, show that the induced potential difference between the electrodes can be controlled by altering the external electric field or by using different microbands in the microband array. As the obtained currents depend on the concentrations of electroactive species in the flowing solution and the detection can be carried out anywhere within the channel without interference of the external electric field, the present approach significantly facilitates electrochemical detection in capillary electrophoresis. This approach consequently holds great promise for application in inexpensive portable chip-based capillary electrophoresis (CE) devices.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Adami, Hans Olov (1); Stattin, Pär (1); Wiklund, Fredrik (1); Thibodeau, Stephen N (1); del Campo, Javier (1); Jonsson, Eirikur (1); show more...; Thorleifsson, Gudmar (1); Rafnar, Thorunn (1); Thorsteinsdottir, Un ... (1); Stefansson, Kari (1); Kiemeney, Lambertus ... (1); Sulem, Patrick (1); Gudmundsson, Julius (1); Agnarsson, Bjarni A. (1); Sigurdsson, Asgeir (1); Benediktsdottir, Kri ... (1); Jakobsdottir, Margre ... (1); Kostic, Jelena (1); Magnusdottir, Dropla ... (1); Ghosh, Shyamali (1); Birgisdottir, Birgit ... (1); Blondal, Thorarinn (1); Bergthorsson, Jon T. (1); Gudbjartsson, Daniel (1); Manolescu, Andrei (1); Kristjansson, Kristl ... (1); Suarez, Brian K. (1); Ober, Carole (1); Gronberg, Henrik (1); Catalona, William J. (1); Einarsson, Gudmundur ... (1); Barkardottir, Rosa B ... (1); Gulcher, Jeffrey R. (1); Kong, Augustine (1); Nyholm, Leif (1); Nikolajeff, Fredrik (1); Yaspan, Brian L (1); Swinkels, Dorine W. (1); Schaid, Daniel J (1); Xu, Jianfeng (1); Wiley, Kathleen E (1); Walsh, Patrick C (1); McDonnell, Shannon K (1); Isaacs, William B (1); Lindström, Sara (1); Wang, Liang (1); Cerhan, James R. (1); Cunningham, Julie M. (1); Zheng, S Lilly (1); Sun, Jielin (1); show less...

University: Umeå University (1); Uppsala University (1); Karolinska Institutet (1)

Language: English (2)

Research subject (UKÄ/SCB): Natural sciences (1)

Year: 2008 (2)Undo refine

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