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- Jönsson, K. Ingemar, 1959-, et al.
(author)
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Sexual patterns of prebreeding energy reserves in the common frog Rana temporaria along a latitudinal gradient
- 2009
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In: Ecography. - : Wiley-Blackwell. - 0906-7590 .- 1600-0587. ; 32:5, s. 831-839
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Journal article (peer-reviewed)abstract
- The ability to store energy is an important life history trait for organisms facing long periods without energy income, and in particular for capital breeders such as temperate zone amphibians, which rely on stored energy during reproduction. However, large scale comparative studies of energy stores in populations with different environmental constraints on energy allocation are scarce. We investigated energy storage patterns in spring (after hibernation and before reproduction) in eight common frog (Rana temporaria) populations exposed to different environmental conditions along a 1600 km latitudinal gradient across Scandinavia (range of annual activity period 3-7 months). Analyses of lean body weight (eviscerated body mass), weight of fat bodies, liver weight, and liver fat content, showed that (i) post-hibernation/pre-breeding energy stores increased with increasing latitude in both sexes, (ii) males generally had larger energy reserves than females and (iii) the difference in energy stores between sexes decreased towards the north. Larger energy reserves towards the north can serve as a buffer against less predictable and/or less benign weather conditions during the short activity period, and may also represent a risk-averse tactic connected with a more pronounced iteroparous life history. In females, the continuous and overlapping vitellogenic activity in the north may also demand more reserves in early spring. The general sexual difference could be a consequence of the fact that, at the time of our sampling, females had already invested their energy into reproduction in the given year (i.e. their eggs were already ovulated), while the males' main reproductive activities (e.g. calling, mate searching, sexual competition) occurred later in the season.
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- Knutsen Rydberg, Ellen, 1969, et al.
(author)
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Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages
- 2004
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In: Arterioscler Thromb Vasc Biol. ; 24:11, s. 2040-2045
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Journal article (peer-reviewed)abstract
- OBJECTIVE: Macrophage-mediated oxidation of low-density lipoprotein (LDL) by enzymes, such as the lipoxygenases, is considered of major importance for the formation of oxidized LDL during atherogenesis. Macrophages have been identified in hypoxic areas in atherosclerotic plaques. METHODS AND RESULTS: To investigate the role of hypoxia in macrophage-mediated LDL oxidation, we incubated human monocyte-derived macrophages with LDL under normoxic (21% O2) or hypoxic (0% O2) conditions. The results showed that hypoxic macrophages oxidized LDL to a significantly higher extent than normoxic cells. Interestingly, the mRNA and protein expression of 15-lipoxygenase-2 (15-LOX-2) as well as the activity of this enzyme are elevated in macrophages incubated at hypoxia. Both the unspliced 15-LOX-2 and the spliced variant 15-LOX-2sv-a are found in macrophages. In addition, 15-LOX-2 was identified in carotid plaques in some macrophage-rich areas but was only expressed at low levels in nondiseased arteries. CONCLUSIONS: In summary, these observations show for the first time that 15-LOX-2 is expressed in hypoxic macrophages and in atherosclerotic plaques and suggest that 15-LOX-2 may be one of the factors involved in macrophage-mediated LDL oxidation at hypoxia.
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- Stobaeus, Per, et al.
(author)
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En bukett av bibliska blomster
- 2008
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In: Förbistringar och förklaringar: festskrift till Anders Piltz. - 9789187976292 ; , s. 575-585
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Book chapter (other academic/artistic)
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- Ambjörn, Lena, et al.
(author)
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Gifter, droger och mat : om läkemedel i den medeltida medicinen i islam
- 2008
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In: Förbistringar och förklaringar : festskrift till Anders Piltz. - 9789187976292 ; , s. 25-33
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Book chapter (pop. science, debate, etc.)abstract
- Drugs prepared from organic and mineral substances have, throughout history, held a central position when it comes to preventing and curing disease. In Galenic medicine, foodstuffs, drugs and deadly substances, or poisons, were all accredited with the potential to affect the constitution of the body. While the Galenic paradigm continued to dominate formal medicine in the Middle Ages, the language used for scientific communication changed from Greek and Syriac to Arabic. This means that our knowledge of most aspects of medieval highly qualified medicine depends on the study of Arabic sources. The preserved Arabic material on pharmacology is extensive, and it is clear that physicians in the Arabo-Islamic cultural sphere have contributed to the knowledge of both single substances and compound preparations.
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| 9. |
- Andersson, Martin, et al.
(author)
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HFSZEEMAN - A program for computing weak and intermediate field fine and hyperfine structure Zeeman splittings from MCDHF wave functions
- 2008
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In: Computer Physics Communications. - : Elsevier BV. - 0010-4655 .- 1879-2944. ; 178:2, s. 156-170
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Journal article (peer-reviewed)abstract
- Given electronic wave functions generated by the grasp2K relativistic atomic structure package, this program calculates diagonal magnetic dipole A(J) and electric quadrupole B-J hyperfine interaction constants and Lande g(J) factors. In addition the program computes diagonal and off-diagonal reduced hyperfine and Zeeman matrix elements and constructs the total interaction matrix for an atom in an external magnetic field. By diagonalizing the interaction matrix and plotting eigenvalues as functions of the magnetic field, Zeeman splittings of hyperfine levels are obtained. The method is applicable in the weak and intermediate field regions and yields results that are useful when analyzing spectra from e.g. EBIT sources and magnetic stars. The program can also be used in the field free limit to calculate mixing coefficients that determine rates of hyperfine induced transitions. For atoms with zero nuclear spin I the program computes splittings of the fine-structure levels. Program summary Program title: HFSZEEMAN Catalogue identifier: ADZS_v1_0 Program summary URL: http://cpc.cs.qub.ac.uk/summaries/ADZS-v1-0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 1528 No. of bytes in distributed program, including test data, etc.: 294 664 Distribution format: tar.gz Programming language: Fortran, Matlab Computer: IBM-compatible PC, unix workstation Operating system: Unix, Linux Classification: 11.6 Subprograms used: Cat Id: ADZL_v1_0; Title: grasp2K v1.0; Reference: CPC 177 (2007) 597 Nature of problem: Prediction of weak and intermediate field Zeeman splittings of fine- and hyperfine structure levels using multiconfiguration Dirac-Hartree-Fock wave functions. Solution method: The electronic wave function for a state labeled Gamma JM is expanded in terms of jj-coupled configuration state functions vertical bar Gamma JM > = Sigma(gamma)c(gamma)vertical bar gamma JM >. In this representation the reduced matrix elements used to construct the interaction matrix can be computed as sums over one-particle radial integrals. By diagonalizing the interaction matrix and plotting eigenvalue as functions of the magnetic field, Zeeman splittings of fine- and hyperfine structure levels are obtained. Restrictions: The complexity of the cases that can be handled is entirely determined by the grasp2K package [P. Jonsson, H. Xe, C. Froese Fischer, I.P. Grant, Comput. Phys. Commun. 177 (2007) 597] used for the generation of the electronic wave functions. Running time: CPU time required to execute test cases: a few seconds.
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| 10. |
- Andersson, Martin, et al.
(author)
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Hyperfine induced interference effects in the 4s4d 3D2–4s4f 3F2,3 transitions in Ga II
- 2006
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In: Journal of Physics B. - : Bibliopolis, Edizioni di Filosofia e Scienze. - 0953-4075 .- 1361-6455. ; 39:20, s. 4239-4247
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Journal article (peer-reviewed)abstract
- We report relativistic multiconfiguration Dirac–Hartree–Fock calculations of transitions between the hyperfine levels of 4s4f 3F2,3 and 4s4d 3D2 in Ga II. The capacity of two newly developed programs connected to the graspVU package for generating synthetic spectra is explored. The obtained theoretical spectra are compared to Fourier transform spectra and good agreement is found. The importance of hyperfine induced interference effects for the 4s4d 3D2–4s4f 3F2 transitions is pointed out, and the gf values for all the hyperfine transitions are given.
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