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| 2. |
- Jansson, Patrik, 1972, et al.
(author)
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Polytypic Compact Printing and Parsing
- 1999
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In: European Symposium on Programming. ; 1576, s. 273-287
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Conference paper (peer-reviewed)abstract
- A generic compact printer and a corresponding parser are constructed. These programs transform values of any regular datatype to and from a bit stream. The algorithms are constructed along with a proof that printing followed by parsing is the identity. Since the binary representation is very compact, the printer can be used for compressing data - possibly supplemented with some standard algorithm for compressing bit streams. The compact printer and the parser are described in the polytypic Haskell extension PolyP.
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| 3. |
- Svensson, Johan, 1964, et al.
(author)
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Treatment of obese subjects with the oral growth hormone secretagogue MK-677 affects serum concentrations of several lipoproteins, but not lipoprotein(a).
- 1999
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In: The Journal of clinical endocrinology and metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 84:6, s. 2028-33
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Journal article (peer-reviewed)abstract
- Obesity is associated with blunted GH secretion and an unfavorable lipoprotein pattern. The objective of this study was to investigate the effects of treatment with the oral GH secretagogue MK-677 on lipoproteins in otherwise healthy obese males. The study was randomized, double blind, and parallel. Twenty-four obese males, aged 18-50 yr, with body mass index greater than 30 kg/m2 and waist/hip ratio above 0.95 were treated with 25 mg MK-677 (n = 12) or placebo (n = 12) daily for 8 weeks. MK-677 treatment did not significantly change serum lipoprotein(a) [Lp(a)] levels. Serum apolipoprotein A-I and E (apoA-I and apoE) were increased at 2 weeks (P < 0.001 and P < 0.01 vs. placebo, respectively), but were not changed at study end. Serum total cholesterol and low density lipoprotein (LDL) cholesterol (LDL-C) levels were not significantly changed by MK-677 treatment. Serum high density lipoprotein (HDL) cholesterol (HDL-C) was increased at 2 weeks of MK-677 treatment (P < 0.01 vs. placebo), but not at 8 weeks. The LDL-C/HDL-C ratio was reduced after 8 weeks of MK-677 treatment (P < 0.05 vs. placebo). Mean LDL particle diameter was decreased at 2 weeks (P < 0.05 vs. placebo), but was unchanged compared with baseline values at 8 weeks (P = NS vs. placebo). The level of serum triglycerides was increased at 2 (P < 0.05 vs. placebo), but not at 8, weeks. Lipoprotein lipase activity in abdominal and gluteal sc adipose tissue was not affected by active treatment. In conclusion, treatment with the oral GH secretagogue MK-677 affected circulating lipoproteins. The effects on serum apoA-1, apoE, triglycerides, and mean LDL particle diameter were transient. At study end, the LDL-C/HDL-C ratio was decreased. MK-677 treatment did not significantly affect serum Lp(a) concentrations at the present dose and administration protocol.
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| 4. |
- Wikner, Johan, 1961-, et al.
(author)
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Differences in consumption of allochthonous DOC under limnic and estuarine conditions in a watershed
- 1999
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In: Aquatic Microbial Ecology. - Oldendorf : Inter-Research. - 0948-3055 .- 1616-1564. ; 17:3, s. 289-299
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Journal article (peer-reviewed)abstract
- A temporal study of the bacterial utilisation of allochthonous dissolved organic carbon (DOC) was performed in a lake and estuary situated in the same boreal watershed. A greater utilisation of allochthonous DOC was observed under estuarine as compared to Limnic conditions. However, the bacterial biomass yield was not significantly different between the environments, indicating a lower growth efficiency on allochthonous DOC by the estuarine bacterioplankton. The largest fraction of the allochthonous DOC utilised (20 %) was observed under estuarine conditions and coincided with the spring flood. The utilisation of allochthonous DOC and bacterial biomass yield in the experimental bottles was Limited by the availability of nitrogen or phosphorus in both environments. Our results showed that the major bacterial transformation of DOC occurred in the estuarine rather than the Limnic environment, due to the shift in physicochemical milieu and bacterial assemblage. However, the estuarine bacteria also respired a greater fraction of the DOC utilised than their limnic counterparts.
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