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Sökning: WFRF:(Johansson Evelina) > (2015-2019)

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1.
  • Carvalho-Queiroz, Claudia, et al. (författare)
  • Associations between EBV and CMV Seropositivity, Early Exposures, and Gut Microbiota in a Prospective Birth Cohort : A 10-Year Follow-up
  • 2016
  • Ingår i: Frontiers in Pediatrics. - : Frontiers Media SA. - 2296-2360. ; 4
  • Tidskriftsartikel (refereegranskat)abstract
    • Early-life infections with persistent Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are delayed in affluent countries, probably due to alterations in early environmental exposures, such as maternal age, siblings, and day-care attendance. We have previously reported that the timing of EBV and CMV contraction is related both to allergic sensitization and changes in functional competence of immune cells, while the presence/absence of lactobacilli [Lactobacillus (L.) casei, L. paracasei, and L. rhamnosus] or Staphylococcus (S.) aureus in feces is related to the risk for allergy. Here, we used the same prospective longitudinal birth cohort of children to investigate early-life environmental exposures and their influence on EBV and CMV contraction over time. Since gut microbes also belong to this category of early exposures, we investigated their association with herpesvirus contraction. Our results show that these two viruses are acquired with different kinetics and that EBV and CMV seroprevalence at 10 years of age was 47 and 57%, respectively. We also observed that a delayed EBV or CMV infection was associated with older maternal age [time ratio (TR) 1.14, 95% confidence interval (CI) 1.07-1.21, P-adj < 0.001 and TR 1.09, CI 1.03-1.16, P-adj = 0.008, respectively]. Further, we present the novel finding that S. aureus colonization reduced the time to CMV acquisition (TR 0.21, CI 0.06-0.78, = 0.02). Together, these findings suggest that there is a relationship between timing of herpesvirus acquisition and early-life immune modulating exposures, which interestingly also includes the early infant gut microbiota.
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2.
  • Falkenjack, Johan, 1986-, et al. (författare)
  • Services for Text Simplification and Analysis
  • 2017
  • Ingår i: Proceedings of the 21st Nordic Conference on Computational Linguistics, NoDaLiDa. - : Linköping University Electronic Press. - 9789176856017 ; , s. 309-313
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • We present a language technology servicefor web editors’ work on making textseasier to understand, including tools fortext complexity analysis, text simplification and text summarization. We alsopresent a text analysis service focusing onmeasures of text complexity.
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