| 51. |
- Blagorodnova, N., et al.
(författare)
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Progenitor, precursor, and evolution of the dusty remnant of the stellar merger M31-LRN-2015
- 2020
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press. - 0035-8711 .- 1365-2966. ; 496:4, s. 5503-5517
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Tidskriftsartikel (refereegranskat)abstract
- M31-LRN-2015 is a likely stellar merger discovered in the Andromeda Galaxy in 2015. We present new optical to mid-infrared photometry and optical spectroscopy for this event. Archival data show that the source started to brighten similar to 2 yr before the nova event. During this precursor phase, the source brightened by similar to 3 mag. The light curve at 6 and 1.5 months before the main outburst may show periodicity, with periods of 16 +/- 0.3 and 28.1 +/- 1.4 d, respectively. This complex emission may be explained by runaway mass-loss from the system after the binary undergoes Roche lobe overflow, leading the system to coalesce in tens of orbital periods. While the progenitor spectral energy distribution shows no evidence of pre-existing warm dust in the system, the remnant forms an optically thick dust shell at approximately four months after the outburst peak. The optical depth of the shell increases dramatically after 1.5 yr, suggesting the existence of shocks that enhance the dust formation process. We propose that the merger remnant is likely an inflated giant obscured by a cooling shell of gas with mass similar to 0.2 M-circle dot ejected at the onset of the common envelope phase.
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| 52. |
- Brady, Mark V., et al.
(författare)
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Att se skogens alla värden – en samhällsekonomisk analys
- 2021
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Ingår i: Policy brief / AgriFood Economics Centre.
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Det pågår en intensiv debatt om hur vi bäst kan använda skogen som resurs. Att ersätta fossila bränslen med förnybara bränslen från den svenska skogen lyfts fram som ett sätt att bidra till klimatmål. Men ett ökat uttag av biomassa kräver att skogen brukas mer intensivt vilket kan vara negativt för en rad andra samhällsmål som skogen bidrar till. Vad skulle ett intensivare skogsbruk totalt sett betyda för samhället? Resultaten visar att:- Skogen bidrar med stora värden till samhället utöver produktionen av biomassa.- När hänsyn även tas till sociala och miljömässiga värden kan ett mer intensivt skogsbruk än idag vara negativt för samhället.- Ett mer varierat skogsbruk, som exempelvis inkluderar hyggesfritt bruk, kan ge större värden både idag och för framtida generationer.
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| 53. |
- Brethouwer, Gert, et al.
(författare)
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Turbulence and cyclic bursts in rotating channel flow
- 2020
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Ingår i: ETC 2013 - 14th European Turbulence Conference. - : Zakon Group LLC.
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Konferensbidrag (refereegranskat)abstract
- DNS have been performed of turbulent channel flow with spanwise rotation and bulk Reynolds number Re up to 30000. At moderate rotation rates Ro the flow on one side of the channel is approximately laminar, or has turbulent patches or oblique turbulent-laminar patterns. Intense cyclic bursts of turbulence with long time intervals are in some cases observed at sufficiently high Re and Ro. A linear analysis indicates that the turbulence bursts are initiated by a linear instability of plane waves aligned with the rotation axis. This linear instability can develop even if parts of the flow are strongly turbulent.
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| 54. |
- Breton, Gwenna, et al.
(författare)
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Comparison of sequencing data processing pipelines and application to underrepresented African human populations
- 2021
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Ingår i: BMC Bioinformatics. - : BioMed Central (BMC). - 1471-2105. ; 22:1
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Tidskriftsartikel (refereegranskat)abstract
- Background Population genetic studies of humans make increasing use of high-throughput sequencing in order to capture diversity in an unbiased way. There is an abundance of sequencing technologies, bioinformatic tools and the available genomes are increasing in number. Studies have evaluated and compared some of these technologies and tools, such as the Genome Analysis Toolkit (GATK) and its "Best Practices" bioinformatic pipelines. However, studies often focus on a few genomes of Eurasian origin in order to detect technical issues. We instead surveyed the use of the GATK tools and established a pipeline for processing high coverage full genomes from a diverse set of populations, including Sub-Saharan African groups, in order to reveal challenges from human diversity and stratification. Results We surveyed 29 studies using high-throughput sequencing data, and compared their strategies for data pre-processing and variant calling. We found that processing of data is very variable across studies and that the GATK "Best Practices" are seldom followed strictly. We then compared three versions of a GATK pipeline, differing in the inclusion of an indel realignment step and with a modification of the base quality score recalibration step. We applied the pipelines on a diverse set of 28 individuals. We compared the pipelines in terms of count of called variants and overlap of the callsets. We found that the pipelines resulted in similar callsets, in particular after callset filtering. We also ran one of the pipelines on a larger dataset of 179 individuals. We noted that including more individuals at the joint genotyping step resulted in different counts of variants. At the individual level, we observed that the average genome coverage was correlated to the number of variants called. Conclusions We conclude that applying the GATK "Best Practices" pipeline, including their recommended reference datasets, to underrepresented populations does not lead to a decrease in the number of called variants compared to alternative pipelines. We recommend to aim for coverage of > 30X if identifying most variants is important, and to work with large sample sizes at the variant calling stage, also for underrepresented individuals and populations.
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| 55. |
- Brett, Calvin
(författare)
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Neutron and X-ray Surface Scattering Reveals the Morphology of Soft Matter Thin Films
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The last decades have been overshadowed by reports about the seemingly endless increase use of fossil-based resources. With the development of new products, our mindset is changing so that we more and more need to consider sustainability in our daily lives. Furthermore, smarter devices are indispensable in our world and daily life, and these are expected to be smaller and smaller in size.To support the transition from fossil-based to sustainable materials, we need to develop knowledge of new materials. Within this thesis project, the aim has been to understand the thin-film properties of sustainable materials and to develop methodologies to measure these. As sustainable template material wood-based nanocellulose was chosen as a bio-degradable representative with favourable favourable physical properties, such as lightweight, transparency, and flexibility. These properties make nanocellulose a perfect candidate for future advanced applications in thin-film organic solar cells, supercapacitors, or sensors. Nanocellulose comprises only a part of such a device, and hence the relevant functional materials and their combinations have to be studied to reveal the interaction between multiple material components on the final device performance. As the nanoscale, or even Ångstrom scale, governs the macroscopic physical properties, it is crucial to understand the materials in detail. Ergo, neutron and X-ray surface-sensitive scattering methods were applied to study nanoparticle deposition layering kinetics and the effects of environmental changes, which revealed the morphology of the resulting nanoporous nanocellulose thin films. The knowledge was used to infiltrate water-soluble intrinsic conductive polymers into these nanopores, which serves as a model for transparent but conductive templates for organic electronics. By changing the environment of the films through humidity cycling, the impact of the environment during a real-life application could be illustrated. Neutron scattering experiments also showed that the cellulose-conductive polymer composite (or hybridmaterial) changes irreversibly during humidity cycling while the pure nanocellulose films show fully reversible properties.Furthermore, the thermal decomposition of silver nitrate deposited on nanocellulose was studied to understand the nanofibrils' impact on the synthesis of nanoparticles. The transparency allowed in situ studies of the synthesis process, the spectroscopic properties as well as the plasmonic effect, which demonstrated routes for minimal material usage concepts for surface synthesis processes. It was also discovered that the process allows for band-gap tuning, which can be directly be applied in organic solar cells to tailor the band-gap to be adapted and hence increasing the efficiency.The morphological properties, as studied using X-rays and neutrons, were correlated to macroscopic properties by measuring wettability, surface topography, spectroscopy, or conductivity to examine the full materials application possibilities. Neutron and X-ray scattering methods are complementary and wisely combined, thus allowed pioneering studies of bio-based sustainable nanocomposites leading to advanced functional material concepts that support the development of devices using less fossil-based materials.
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| 56. |
- Budeus, B., et al.
(författare)
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamics
- 2021
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Ingår i: Journal of Immunology. - : The American Association of Immunologists. - 0022-1767 .- 1550-6606. ; 206:12, s. 2839-2851
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Tidskriftsartikel (refereegranskat)abstract
- Neonatal and infant immune responses are characterized by a limited capability to generate protective Ab titers and memory B cells as seen in adults. Multiple studies support an immature or even impaired character of umbilical cord blood (UCB) B cells themselves. In this study, we provide a comprehensive molecular and functional comparison of B cell subsets from UCB and adult peripheral blood. Most UCB B cells have a mature, naive B cell phenotype as seen in adults. The UCB Ig repertoire is highly variable but interindividually conserved, as BCR clonotypes are frequently shared between neonates. Furthermore, UCB B cells show a distinct transcriptional program that confers accelerated responsiveness to stimulation and facilitated IgA class switching. Stimulation drives extensive differentiation into Ab-secreting cells, presumably limiting memory B cell formation. Humanized mice suggest that the distinctness of UCB versus adult B cells is already reflected by the developmental program of hematopoietic precursors, arguing for a layered B-1/B-2 lineage system as in mice, albeit our findings suggest only partial comparability to murine B-1 cells. Our study shows that UCB B cells are not immature or impaired but differ from their adult mature counterpart in a conserved BCR repertoire, efficient IgA class switching, and accelerated, likely transient response dynamics. © 2021 by TheAmericanAssociation of Immunologists, Inc.
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| 57. |
- Callaghan, Terry V., et al.
(författare)
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Improving dialogue among researchers, local and indigenous peoples and decision-makers to address issues of climate change in the North
- 2020
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Ingår i: Ambio: a Journal of the Human Environment. - : Springer Science and Business Media LLC. - 0044-7447. ; 49:6, s. 1161-1178
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Tidskriftsartikel (refereegranskat)abstract
- The Circumpolar North has been changing rapidly within the last decades, and the socioeconomic systems of the Eurasian Arctic and Siberia in particular have displayed the most dramatic changes. Here, anthropogenic drivers of environmental change such as migration and industrialization are added to climate-induced changes in the natural environment such as permafrost thawing and increased frequency of extreme events. Understanding and adapting to both types of changes are important to local and indigenous peoples in the Arctic and for the wider global community due to transboundary connectivity. As local and indigenous peoples, decision-makers and scientists perceive changes and impacts differently and often fail to communicate efficiently to respond to changes adequately, we convened a meeting of the three groups in Salekhard in 2017. The outcomes of the meeting include perceptions of how the three groups each perceive the main issues affecting health and well-being and recommendations for working together better.
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| 58. |
- Callaghan, Terry V, et al.
(författare)
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Snow, ice and the biosphere
- 2021. - 2
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Ingår i: Snow and ice-related hazards, risks, and disasters.. - 9780128171295 ; , s. 137-164
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Bokkapitel (refereegranskat)
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| 59. |
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| 60. |
- Dobrota, Ana S., et al.
(författare)
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Altering the reactivity of pristine, N- and P-doped graphene by strain engineering : A DFT view on energy related aspects
- 2020
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Ingår i: Applied Surface Science. - : ELSEVIER. - 0169-4332 .- 1873-5584. ; 514
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Tidskriftsartikel (refereegranskat)abstract
- For carbon-based materials, in contrast to metal surfaces, a general relationship between strain and reactivity is not yet established, even though there are literature reports on strained graphene. Knowledge of such relationships would be extremely beneficial for understanding the reactivity of graphene-based surfaces and finding optimisation strategies which would make these materials more suitable for targeted applications. Here we investigate the effects of compressive and tensile strain (up to +/- 5%) on the structure, electronic properties and reactivity of pure, N-doped and P-doped graphene, using DFT calculations. We demonstrate the possibility of tuning the topology of the graphene surface by strain, as well as by the choice of the dopant atom. The reactivity of (doped) strained graphene is probed using H and Na as simple adsorbates of great practical importance. Strain can both enhance and weaken H and Na adsorption on (doped) graphene. In case of Na adsorption, a linear relationship is observed between the Na adsorption energy on P-doped graphene and the phosphorus charge. A linear relationship between the Na adsorption energy on flat graphene surfaces and strain is found. Based on the adsorption energies and electrical conductivity, potentially good candidates for hydrogen storage and sodiumion battery electrodes are discussed.
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