| 1. |
- Abazov, V. M., et al.
(författare)
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The upgraded DO detector
- 2006
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 565:2, s. 463-537
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Tidskriftsartikel (refereegranskat)abstract
- The DO experiment enjoyed a very successful data-collection run at the Fermilab Tevatron collider between 1992 and 1996. Since then, the detector has been upgraded to take advantage of improvements to the Tevatron and to enhance its physics capabilities. We describe the new elements of the detector, including the silicon microstrip tracker, central fiber tracker, solenoidal magnet, preshower detectors, forward muon detector, and forward proton detector. The uranium/liquid -argon calorimeters and central muon detector, remaining from Run 1, are discussed briefly. We also present the associated electronics, triggering, and data acquisition systems, along with the design and implementation of software specific to DO.
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| 2. |
- Abazov, M, et al.
(författare)
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Measurement of the W Boson Mass
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:14, s. 141801-
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Tidskriftsartikel (refereegranskat)abstract
- We present a measurement of the W boson mass in W -> e nu decays using 1 fb(-1) of data collected with the D0 detector during Run II of the Fermilab Tevatron collider. With a sample of 499830 W -> e nu candidate events, we measure M-W=80.401 +/- 0.043 GeV. This is the most precise measurement from a single experiment.
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| 3. |
- Abazov, M, et al.
(författare)
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Direct Measurement of the W Boson Width
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:23, s. 231802-
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Tidskriftsartikel (refereegranskat)abstract
- We present a direct measurement of the width of the W boson using the shape of the transverse mass distribution of W -> e nu candidate events. Data from approximately 1 fb(-1) of integrated luminosity recorded at s=1.96 TeV by the D0 detector at the Fermilab Tevatron pp collider are analyzed. We use the same methods and data sample that were used for our recently published W boson mass measurement, except for the modeling of the recoil, which is done with a new method based on a recoil library. Our result, 2.028 +/- 0.072 GeV, is in agreement with the predictions of the standard model.
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| 4. |
- Abazov, M, et al.
(författare)
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A novel method for modeling the recoil in W boson events at hadron colliders
- 2009
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 609:2-3, s. 250-262
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Tidskriftsartikel (refereegranskat)abstract
- We present a new method for modeling the hadronic recoil in W -> lv events produced at hadron colliders. The recoil is chosen from a library of recoils in Z -> ll data events and overlaid on a simulated W -> lv event. Implementation of this method requires that the data recoil library describe the proper-ties of the measured recoil as a function of the true, rather than the measured, transverse momentum of the boson. We address this issue using a multidimensional Bayesian unfolding technique. We estimate the statistical and systematic uncertainties from this method for the W boson mass and width measurements assuming 1 fb(-1) of data from the Fermilab Tevatron. The uncertainties are found to be small and comparable to those of a more traditional parameterized recoil model. For the highprecision measurements that will be possible with data from Run 11 of the Fermilab Tevatron and from the CERN LHC, the method presented in this paper may be advantageous, since it does not require an understanding of the measured recoil from first principles.
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| 5. |
- Aulchenko, Yurii S, et al.
(författare)
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Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
- 2009
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 41:1, s. 47-55
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Tidskriftsartikel (refereegranskat)abstract
- Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides sampled randomly from 16 population-based cohorts and genotyped using mainly the Illumina HumanHap300-Duo platform. Our study included a total of 17,797-22,562 persons, aged 18-104 years and from geographic regions spanning from the Nordic countries to Southern Europe. We established 22 loci associated with serum lipid levels at a genome-wide significance level (P < 5 x 10(-8)), including 16 loci that were identified by previous GWA studies. The six newly identified loci in our cohort samples are ABCG5 (TC, P = 1.5 x 10(-11); LDL, P = 2.6 x 10(-10)), TMEM57 (TC, P = 5.4 x 10(-10)), CTCF-PRMT8 region (HDL, P = 8.3 x 10(-16)), DNAH11 (LDL, P = 6.1 x 10(-9)), FADS3-FADS2 (TC, P = 1.5 x 10(-10); LDL, P = 4.4 x 10(-13)) and MADD-FOLH1 region (HDL, P = 6 x 10(-11)). For three loci, effect sizes differed significantly by sex. Genetic risk scores based on lipid loci explain up to 4.8% of variation in lipids and were also associated with increased intima media thickness (P = 0.001) and coronary heart disease incidence (P = 0.04). The genetic risk score improves the screening of high-risk groups of dyslipidemia over classical risk factors.
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| 6. |
- Nene, Vishvanath, et al.
(författare)
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Genome sequence of Aedes aegypti, a major arbovirus vector.
- 2007
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 316:5832, s. 1718-23
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Tidskriftsartikel (refereegranskat)abstract
- We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae. Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of approximately 4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster. Nonetheless, chromosomal synteny is generally maintained among all three insects, although conservation of orthologous gene order is higher (by a factor of approximately 2) between the mosquito species than between either of them and the fruit fly. An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species.
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| 7. |
- Brown, Kevin M., et al.
(författare)
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Common sequence variants on 20q11.22 confer melanoma susceptibility
- 2008
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 40:7, s. 838-840
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Tidskriftsartikel (refereegranskat)abstract
- We conducted a genome-wide association pooling study for cutaneous melanoma and performed validation in samples totaling 2,019 cases and 2,105 controls. Using pooling, we identified a new melanoma risk locus on chromosome 20 (rs910873 and rs1885120), with replication in two further samples (combined P < 1 x 10(-15)). The per allele odds ratio was 1.75 (1.53, 2.01), with evidence for stronger association in early-onset cases.
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| 8. |
- Montgomery, William, et al.
(författare)
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A new conceptualization of value structure
- 2008
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Ingår i: ECP 14.
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Konferensbidrag (refereegranskat)abstract
- In Schwartz and Bilsky’s (1989, 1991) theory, values are organized in ten motivational types forming a circumplex structure. We modify the theory by proposing values that more clearly consists of opposite pairs. A given value (e.g., security) in a pair is associated with a positive emotion (feel afe) and a negative emotion (feel bored). The opposite value (e.g. courage) is associated with an opposite positive emotion (feel excited) and a negative emotion (feel afraid). Two surveys employing 144 respectively 120 undergraduates confirmed the proposed circumplex structure of values with positive and negative associated emotions.
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| 9. |
- Montgomery, William, et al.
(författare)
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A new look at value structure
- 2008
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Ingår i: SPSP meeting.
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Konferensbidrag (refereegranskat)abstract
- Schwartz and Bilsky (1989, 1991) assumed that values are organized in ten motivational types that form a circumplex structure. We extend and modify Schwartz and Bilsky’s theory by distinguishing between bipolar and unipolar values. Both types of values are associated with positive emotions. Bipolar values are organized such that a given value (e.g., security) that leads to experience of a given positive emotion (e.g., feel safe) at the expense of another positive emotion related to an opposite value (e.g., feel excited when attaining courage), which in turn implies experiencing a negative emotion (e.g., feel bored) when attaining the former value. Bipolar values are located opposite to each other in a two-dimensional circumplex structure. Unipolar values do not have any opposites. Therefore, they do not lead to any specific negative emotion resulting from decreasing attainment of an opposite value. These expectations were confirmed in two empirical studies. In Study 1 a total of 144 psychology students rated eight bipolar values from different perspectives (access, importance, positivity, ability, and engagement). Multidimensional scaling of the value ratings resulted in a circumplex structure. In Study 2 ratings by participants of 24 emotions in relation to eight bipolar values and four unipolar values revealed that each of the bipolar values were associated with positive and negative emotions. Increases of unipolar values were associated only with positive emotions while decreases were associated only with negative emotions.
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| 10. |
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