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| 2. |
- Anveskog, L., et al.
(författare)
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Att välja rätt standardsystem
- 1984
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Ingår i: Data (Nordisk datanytt), nr 10, 1984, sid. 50-52.
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Tidskriftsartikel (refereegranskat)abstract
- Vi står inför att välja standardsystem. Vårt mål är att standardsystemet skall ge ett effektivt bidrag till verksamheten. Syftet är också att tjäna tid och pengar jämfört med egenutveckling. Et sätt att välja är att köpa det standardsystem som vi omedelbart fastnar för. Risken är då att vi inte ser de svårigheter och nackdelar som ofta finns. Vi bländas lätt av de positiva möjligheter som erbjuds genom standardsystemet. Vi går in i valprocessen med en förutfattad mening.Ett alternativt sätt att välja är att mera noggrant jämföra tänkbara standardsystem mot den egna verksamheten. Vi behöver då ta ställning till en mångfald olika faktorer för att kunna välja "rätt" standardsystem. En systematisk metod hjälper oss att få en överblick. Vi får en säker grund att stå på för att dra riktiga slutsatser om standardsystemens möjligheter och brister
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| 3. |
- Anveskog, L., et al.
(författare)
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Verksamhetsutveckling - Att välja standardsystem
- 1984
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Bok (refereegranskat)abstract
- De flesta företag köper idag färdiga standardsystem, i stället för att programmera, när man datoriserar olika rutiner.Att välja system innebär att vi jämför företagets behov med vad som finns på marknaden. Arbetet kan ses som en beslutsprocess där vi successivt väljer bort standardsystem så att till slut det "bästa" alterntivet återstår. Boken presenterar en metod för bättre planering av Standardsystem I Verksamheter (SIV) med tonvikt på valproblematiken. SIV-metoden omfattar ett antal steg, behovsnanalys, förutsättningsanalys, markandsundersökning, leverantörsbedömning, offertbegäran, jämförelse, urval, demonstration, behovskomplettering, utvärdering, preliminärval, testkörning, förhandling, beslut och delgivning.Ibland behöver vi ändå förändra standardsystemet och/eller den egna verksamheten. En metod för detta presenteras i boken: " Verksamhetsutveckling - Att anpassa standardsystem" (Studenlitteratur, 1983) som kan ses som ett komplement till denna bok.Boken var förpublicerad som V-rapport V-4302, Institutet för Verksamhetsutveckling (Institut V) vid Handelshögskolan i Stockholm (1983-12-01)
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| 4. |
- de Luca, S., et al.
(författare)
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Proteoglycans from chick limb bud chondrocyte cultures. Keratan sulfate and oligosaccharides which contain mannose and sialic acid
- 1980
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Ingår i: Journal of Biological Chemistry. - 0021-9258. ; 255:13, s. 6077-6083
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Tidskriftsartikel (refereegranskat)abstract
- The precursors, [ 35S]sulfate and [2- 3H]mannose, were used to study the biosynthesis of keratan sulfate and other oligosaccharides on proteoglycans isolated from Day 8 cultures of chick limb bud chondrocytes. After alkaline borohydride treatment, three fractions with sialic acid were separated by molecular sieve chromatography. The first contained keratan sulfate which was purified by digestion with chondroitinase to remove chondroitin sulfate, followed by molecular sieve and ion exchange chromatography. The purified keratan sulfate contained about 8% of the 35S activity originally in monomer. The chains had an average length of about 40 monosaccharides and contained only trace amounts of mannose (less than 1 residue/three to four chains). The second fraction contained the majority of the [ 3H]mannose originally in monomer, but no 35S activity. This fraction appears to contain oligosaccharide-peptides of the asparagine-N-glycosylamine type because there were no reduced sugars present and the alkaline borohydride treatment extensively degraded the core protein. The composition of the oligosaccharides, with high proportions of mannose, N-acetylglucosamine, galactose, and sialic acid, was consistent with this suggestion. The third fraction consisted of a series of oligosaccharides with sizes between three to six saccharides. They contained N-acetylgalactosaminitol, indicating that they were attached to the core protein by O-glycoside bonds between N-acetylgalactosamine and hydroxyl groups on serine and threonine. Thus, proteoglycans contain two classes of oligosaccharides, a mannose-rich class characteristic of glycoproteins and an O-glycoside class characteristic of mucins, in addition to the chondroitin sulfate and keratan sulfate chains.
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| 5. |
- Erlinge, S, et al.
(författare)
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Predation on brown hare and ring-necked pheasant populations on southern Sweden
- 1984
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Ingår i: Holarctic Ecology. ; 7:3, s. 300-304
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Tidskriftsartikel (refereegranskat)abstract
- in an open field area in southern Sweden. Biomass and numbers of hares and pheasants eaten by the predators were calculated from data on food habits, food requirements, and numbers of the mammalian and avian predators present (11 species). At the same time estimates of numbers and production of hares and pheasants were obtained. At least 40% of the estimated annual production of hares and almost 60% of subadult-adultp heasants in autumn were consumed by the predators. Estimated numbers of hares and pheasants taken by the predators greatly exceeded shootinga nd road mortality.F oxes and cats were the predominantp reda-tors on hares( about9 0%o f total harec onsumption). Foxesa ccountedf or aboutt wo-thirds of predation on pheasants; cats and goshawks were of secondary importance. Pheasant nests were preyed upon by hooded crows and also by badgers. Hares and pheasantsc ontributedo nly about 3 and 1%, respectively,o f the food of the predators.
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| 8. |
- Nilsson, I, et al.
(författare)
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Denitrification of Water Using Immobilized Pseudomonas denitrificans Cells
- 1980
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Ingår i: European Journal of Applied Microbiology and Biotechnology. ; 10, s. 261-274
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Tidskriftsartikel (refereegranskat)abstract
- Preparations of living Pseudomonas denitrificans cells immobilized in alginate gel were used in the denitrification of water. In the presence of an exogenous carbon source the entrapped microorganisms reduced nitrate and nitrite to gaseous products and to achieve complete reduction, carbon to nitrogen ratios of over two were required. The effects on denitrification of particle size and the number of bacteria in the gel were investigated. Apparent Km values for nitrate and nitrite reduction were calculated for free and immobilized cells. When the immobilized cells were incubated in nutrient media, an increase in reduction rate was observed and this was shown to be caused by the growth of cells within the gel particles. Immobilized P. denitrificans cells retained 75% of their initial nitrate reduction capacity after 21 days of storage at +4°C. The operational stability of the alginate-immobilized cells was studied both in batch and in a column which was operated continuously. A column (45 g of alginate-cell fibers in 80 ml) denitrified a high nitrate drinking water (100 mg NO3/l) with a rate of 300 ml of nitrate and nitrite free water/day/g of gel. The half life for nitrate reduction was estimated to be 30 days.
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| 9. |
- Nilsson, I. M., et al.
(författare)
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Suppression of Secondary Antibody Response by Intravenous Immunoglobulin in a Patient with Haemophilia B and Antibodies
- 1983
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Ingår i: Scandinavian Journal of Haematology. - : Wiley. - 0036-553X. ; 30:5, s. 458-464
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Tidskriftsartikel (refereegranskat)abstract
- A 39‐year‐old patient, suffering from severe haemophilia B and antibodies against factor IX, has twice been treated with extracorporeal protein A‐Sepharose adsorption followed by conventional substitution therapy in combination with immunosuppression (cyclophos‐phamide). On both occasions, separated by a 2‐year interval, the same procedure was followed except that, on the second, administration of i.v. immunoglobulin (Gammonativ, KabiVitrum) was added. Within a week of the first treatment the patient developed a 15‐fold increase in the antibody titre. Following the second treatment described here, no secondary antibody response could be detected, and after a further 12 weeks only traces of antibodies are demonstrable. It seems that antibody synthesis was suppressed by the i.v. immunoglobulin. No evidence was found to demonstrate that the effect was due either to a non‐specific suppression of the immune and reticuloendothelial systems or to the action of interfering antibodies. It has not yet been established whether or not the protein A‐Sepharose adsorption technique, or the immunosuppressive treatment, contributed in any way to the result. The observations suggest a new approach to the treatment of haemophiliacs with antibodies of the high‐responding type.
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