| 1. |
- Rodrigues, A G, et al.
(författare)
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Germ tube formation changes surface hydrophobicity of Candida cells
- 1999
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Ingår i: Infectious Diseases in Obstetrics and Gynecology. - 1064-7449. ; 7:5, s. 222-226
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Tidskriftsartikel (refereegranskat)abstract
- Hydrophobic interaction is generally considered to play an important role in the adherence of microorganisms to eukaryotic cells and also to certain inert surfaces. Using a microbe adhesion assay to hydrocarbons (n-hexadecane), 68 strains of Candida albicans and 30 non-albicans strains were studied. Influence of source of isolate, age of the culture, and percentage of germ tube formation on adhesion were studied. C. albicans blastoconidia were found to be hydrophilic; conversely, blastoconidia of non-albicans strains were slightly more hydrophobic. Germ tube formation was associated with a significant rise in cell surface hydrophobicity.
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| 2. |
- Rodrigues, A G, et al.
(författare)
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Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines?
- 1999
-
Ingår i: American Journal of Obstetrics and Gynecology. - 1097-6868. ; 181:2, s. 367-370
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE AND STUDY DESIGN: We report for the first time an inhibitory effect on cell division and germ tube formation by Candida albicans and strains of other Candida species by putrescine and cadaverine. RESULTS: Both bacterial amines showed a dose-dependent inhibition of germ tube formation by C albicans, as well as budding (inhibition of cell division) of strains of other Candida species (ie, C glabrata, C krusei, and C tropicalis). CONCLUSIONS: We hypothesize that the presence of these and possibly other bacterial amines produced by anaerobes in the vaginal flora and seen in bacterial vaginosis, as in the healthy gut, may explain why candidosis is rarely seen in these instances.
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