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Numrering	Referens	Omslagsbild	Hitta
1.	Schröder, Fritz H, et al. (författare) Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. 2014 Ingår i: Lancet. - 1474-547X. ; 384:9959 Tidskriftsartikel (refereegranskat)abstract The European Randomised study of Screening for Prostate Cancer (ERSPC) has shown significant reductions in prostate cancer mortality after 9 years and 11 years of follow-up, but screening is controversial because of adverse events such as overdiagnosis. We provide updated results of mortality from prostate cancer with follow-up to 2010, with analyses truncated at 9, 11, and 13 years.
2.	Vedder, Moniek M, et al. (författare) The Added Value of Percentage of Free to Total Prostate-specific Antigen, PCA3, and a Kallikrein Panel to the ERSPC Risk Calculator for Prostate Cancer in Prescreened Men. 2014 Ingår i: European Urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 66:6, s. 1109-1115 Tidskriftsartikel (refereegranskat)abstract Prostate-specific antigen (PSA) testing has limited accuracy for the early detection of prostate cancer (PCa).
3.	Vickers, Andrew J., et al. (författare) Empirical estimates of prostate cancer overdiagnosis by age and prostate-specific antigen 2014 Ingår i: BMC Medicine. - : Springer Science and Business Media LLC. - 1741-7015. ; 12 Tidskriftsartikel (refereegranskat)abstract Background: Prostate cancer screening depends on a careful balance of benefits, in terms of reduced prostate cancer mortality, and harms, in terms of overdiagnosis and overtreatment. We aimed to estimate the effect on overdiagnosis of restricting prostate specific antigen (PSA) testing by age and baseline PSA. Methods: Estimates of the effects of age on overdiagnosis were based on population based incidence data from the US Surveillance, Epidemiology and End Results database. To investigate the relationship between PSA and overdiagnosis, we used two separate cohorts subject to PSA testing in clinical trials (n = 1,577 and n = 1,197) and a population-based cohort of Swedish men not subject to PSA-screening followed for 25 years (n = 1,162). Results: If PSA testing had been restricted to younger men, the number of excess cases associated with the introduction of PSA in the US would have been reduced by 85%, 68% and 42% for age cut-offs of 60, 65 and 70, respectively. The risk that a man with screen-detected cancer at age 60 would not subsequently lead to prostate cancer morbidity or mortality decreased exponentially as PSA approached conventional biopsy thresholds. For PSAs below 1 ng/ml, the risk of a positive biopsy is 65 (95% CI 18.2, 72.9) times greater than subsequent prostate cancer mortality. Conclusions: Prostate cancer overdiagnosis has a strong relationship to age and PSA level. Restricting screening in men over 60 to those with PSA above median (>1 ng/ml) and screening men over 70 only in selected circumstances would importantly reduce overdiagnosis and change the ratio of benefits to harms of PSA-screening.
4.	Carlsson, Sigrid, 1982, et al. (författare) RE: Prostate-specific antigen screening trials and prostate cancer deaths: the androgen deprivation connection. 2014 Ingår i: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 1460-2105 .- 0027-8874. ; 106:5 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
5.	Sooriakumaran, Prasanna, et al. (författare) Comparative effectiveness of radical prostatectomy and radiotherapy in prostate cancer: observational study of mortality outcomes. 2014 Ingår i: BMJ (Clinical research ed.). - : BMJ. - 1756-1833. ; 348 Tidskriftsartikel (refereegranskat)abstract To compare the survival outcomes of patients treated with surgery or radiotherapy for prostate cancer.

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Typ av publikation: tidskriftsartikel (5)

Typ av innehåll: refereegranskat (4); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Roobol, Monique J (5); Lilja, Hans (3); Hugosson, Jonas, 195 ... (2); Carlsson, Sigrid, 19 ... (2); Auvinen, Anssi (2); Vickers, Andrew J. (2); visa fler...; Schröder, Fritz H (2); Ulmert, David (1); Carlsson, Stefan (1); Wiklund, Peter (1); Steineck, Gunnar, 19 ... (1); CARLSSON, STEFAN, 19 ... (1); Holmberg, Erik, 1951 (1); Tammela, Teuvo L.J. (1); Akre, Olof (1); Godtman, Rebecka Arn ... (1); Hakama, Matti (1); Kujala, Paula (1); Taari, Kimmo (1); Aus, Gunnar, 1958 (1); Bangma, Chris H (1); Zappa, Marco (1); Puliti, Donella (1); Denis, Louis J (1); Nelen, Vera (1); Kwiatkowski, Maciej (1); Paez, Alvaro (1); Lujan, Marcos (1); de Koning, Harry J (1); Olsson, Mats (1); van der Kwast, Theo ... (1); Moss, Sue M (1); Steyerberg, Ewout W. (1); Scardino, Peter T. (1); Sjoberg, Daniel D (1); Villers, Arnauld (1); Rebillard, Xavier (1); Recker, Franz (1); Heijnsdijk, Eveline ... (1); Sooriakumaran, Prasa ... (1); van Schaik, Ron H. N ... (1); de Bekker-Grob, Esth ... (1); de Koning, Harry (1); Stenman, Ulf-Hakan (1); Thompson, Ian (1); van Leenders, Geert ... (1); Vertosick, Emily (1); Huber, Andreas (1); Haendler, Leif (1); Määttänen, Liisa (1); visa färre...

Lärosäte: Göteborgs universitet (3); Lunds universitet (3); Chalmers tekniska högskola (1); Karolinska Institutet (1)

Språk: Engelska (5)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (5)

År: 2014 (5)Ta bort avgränsningen

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