| 1. |
- Abulaiti, Yiming, et al.
(författare)
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Measurements of the Higgs boson production and decay rates and constraints on its couplings from a combined ATLAS and CMS analysis of the LHC pp collision data at root s=7 and 8 TeV
- 2016
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Ingår i: Journal of High Energy Physics (JHEP). - : SPRINGER. - 1126-6708 .- 1029-8479. ; :8
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Tidskriftsartikel (refereegranskat)abstract
- Combined ATLAS and CMS measurements of the Higgs boson production and decay rates, as well as constraints on its couplings to vector bosons and fermions, are presented. The combination is based on the analysis of five production processes, namely gluon fusion, vector boson fusion, and associated production with a W or a Z boson or a pair of top quarks, and of the six decay modes H -> ZZ; WW, gamma gamma; tau tau; bb, and mu mu. All results are reported assuming a value of 125: 09 GeV for the Higgs boson mass, the result of the combined measurement by the ATLAS and CMS experiments. The analysis uses the CERN LHC proton-proton collision data recorded by the ATLAS and CMS experiments in 2011 and 2012, corresponding to integrated luminosities per experiment of approximately 5 fb(-1) at root s = 7TeV and 20 fb(-1) at root s = 8TeV. The Higgs boson production and decay rates measured by the two experiments are combined within the context of three generic parameterisations: two based on cross sections and branching fractions, and one on ratios of coupling modifiers. Several interpretations of the measurements with more model-dependent parameterisations are also given. The combined signal yield relative to the Standard Model prediction is measured to be 1.09 +/- 0.11. The combined measurements lead to observed significances for the vector boson fusion production process and for the H -> tau tau decay of 5.4 and 5.5 standard deviations, respectively. The data are consistent with the Standard Model predictions for all parameterisations considered.
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| 2. |
- Abulaiti, Yiming, et al.
(författare)
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Search for single production of a vector-like quark via a heavy gluon in the 4b final state with the ATLAS detector in pp collisions at root s=8 TeV
- 2016
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 758, s. 249-268
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Tidskriftsartikel (refereegranskat)abstract
- A search is performed for the process pp -> G* -> B-H(b) over bar/(B) over bar (H)b -> Hb (b) over bar -> b (b) over barb (b) over bar, predicted in composite Higgs scenarios, where G* is a heavy colour octet vector resonance and B-H a vector-like quark of charge -1/3. The data were obtained from pp collisions at a centre-of-mass energy of 8 TeV corresponding to an integrated luminosity of 19.5 fb(-1), recorded by the ATLAS detector at the LHC. The largest background, multijet production, is estimated using a data-driven method. No significant excess of events with respect to Standard Model predictions is observed, and upper limits on the production cross section times branching ratio are set. Comparisons to the predictions from a specific benchmark model are made, resulting in lower mass limits in the two-dimensional mass plane of m(G*) vs. m(BH).
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| 3. |
- Abulaiti, Yiming, et al.
(författare)
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Search for the Higgs boson produced in association with a W boson and decaying to four b-quarks via two spin-zero particles in pp collisions at 13 TeV with the ATLAS detector
- 2016
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 76:11
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a dedicated search for exotic decays of the Higgs boson to a pair of new spin-zero particles, H -> aa, where the particle a decays to b-quarks and has a mass in the range of 20-60 GeV. The search is performed in events where the Higgs boson is produced in associationwith aW boson, giving rise to a signature of a lepton (electron or muon), missing transverse momentum, and multiple jets from b-quark decays. The analysis is based on the full dataset of pp collisions at root s = 13 TeV recorded in 2015 by theATLAS detector at theCERNLargeHadron Collider, corresponding to an integrated luminosity of 3.2 fb(-1). No significant excess of events above the Standard Model prediction is observed, and a 95% confidence-level upper limit is derived for the product of the production cross section for pp -> WH times the branching ratio for the decay H -> aa -> 4b. The upper limit ranges from 6.2 pb for an a-boson mass m(a) = 20 GeV to 1.5 pb for m(a) = 60 GeV.
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| 4. |
- Bergström, Petra, et al.
(författare)
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Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation
- 2016
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6
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Tidskriftsartikel (refereegranskat)abstract
- Amyloid precursor protein (APP) and its cleavage product amyloid beta (A beta) have been thoroughly studied in Alzheimer's disease. However, APP also appears to be important for neuronal development. Differentiation of induced pluripotent stem cells (iPSCs) towards cortical neurons enables in vitro mechanistic studies on human neuronal development. Here, we investigated expression and proteolytic processing of APP during differentiation of human iPSCs towards cortical neurons over a 100-day period. APP expression remained stable during neuronal differentiation, whereas APP processing changed. alpha-Cleaved soluble APP (sAPP alpha) was secreted early during differentiation, from neuronal progenitors, while beta-cleaved soluble APP (sAPP beta) was first secreted after deep-layer neurons had formed. Short A beta peptides, including A beta 1-15/16, peaked during the progenitor stage, while processing shifted towards longer peptides, such as A beta 1-40/42, when post-mitotic neurons appeared. This indicates that APP processing is regulated throughout differentiation of cortical neurons and that amyloidogenic APP processing, as reflected by A beta 1-40/42, is associated with mature neuronal phenotypes.
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