| 1. |
- Krite Svanberg, Emilie, et al.
(författare)
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Diode laser spectroscopy for non-invasive monitoring of oxygen in the lungs of newborn infants.
- 2016
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Ingår i: Pediatric Research. - : Springer Science and Business Media LLC. - 1530-0447 .- 0031-3998. ; 79, s. 621-628
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Tidskriftsartikel (refereegranskat)abstract
- Newborn infants have pulmonary disorders with abnormal gas distribution, e. g. respiratory distress syndrome. Pulmonary radiography is the clinical routine for diagnosis. Our aim was to investigate a novel non-invasive optical technique for rapid non-radiographic bedside detection of oxygen gas in the lungs of full-term newborn infants.
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| 2. |
- Svanberg, Emilie Krite, et al.
(författare)
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Non-invasive monitoring of oxygen in the lungs of newborn infants using diode laser spectroscopy
- 2016
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Ingår i: Cancer Imaging and Therapy, CANCER 2016. - 9781943580101 ; Part F13-CANCER 2016
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Konferensbidrag (refereegranskat)abstract
- The main purpose of this study was to investigate a novel non-invasive optical technique for rapid bedside detection of oxygen gas in the lungs of full-term newborn infants. The results suggest that the technique will be clinically useful as a diagnostic and monitoring tool for infants with lung disorders.
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| 3. |
- Brydegaard, Mikkel, et al.
(författare)
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Complete parameterization of temporally and spectrally resolved laser induced fluorescence data with applications in bio-photonics
- 2015
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Ingår i: Chemometrics and Intelligent Laboratory Systems. - : Elsevier BV. - 0169-7439. ; 142, s. 95-106
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Tidskriftsartikel (refereegranskat)abstract
- We present a set of spectrally and temporally resolved clinical fluorescence data-with two separate excitation wavelengths-that was recorded in vivo. We demonstrate that data in the spectral and temporal domains are in certain ways coupled and provide a method for integrated and effective parameterization of spectrally and temporally resolved fluorescence (i.e., time-resolved emission spectra). This parameterization is based on linear algebra, matrix formulation and system identification. We demonstrate how to empirically extract single exponentially decaying components and provide rectified emission spectra without prior knowledge. We investigate the potential for improved cancer diagnostics according to the reduced parameters along the various domains. In this case, in terms of cancer diagnostics, we were unable to identify any benefits of simultaneously measuring both the temporal and spectral properties of the observed fluorescence. However, we note that this may be explained by an important experimental bias present in many studies of optical cancer diagnostics, namely, that, in general, suspected lesions always differ visually from the neighboring healthy tissue. (C) 2015 Elsevier B.V. All rights reserved.
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| 4. |
- Huang, Jing, et al.
(författare)
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Assessment of human sinus cavity air volume using tunable diode laser spectroscopy, with application to sinusitis diagnostics.
- 2015
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Ingår i: Journal of Biophotonics. - : Wiley. - 1864-063X. ; 8:11-12, s. 985-992
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Tidskriftsartikel (refereegranskat)abstract
- Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over-prescription of antibiotics. A non-intrusive optical technique called GASMAS (GAs in Scattering Media Absorption Spectroscopy), which has a true potential of being developed into an important complement to other means of detection, was utilized in this work. Water vapor in the frontal sinuses, related to the free gas volume, was studied at around 937 nm in healthy volunteers. The results show a good stability of the GASMAS signals over extended times for the frontal sinuses for all volunteers, showing promising applicability to detect anomalies due to sinusitis. Measurements were also performed following the application of a decongestion spray. No noticeable signal change was observed, which is consistent with the fact that the water vapor concentration is given by the temperature only, and is not influenced by changes in cavity ventilation. Evaluated GASMAS data recorded on 6 consecutive days show signal stability for the left and right frontal sinus in one of the test volonteers.
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| 5. |
- Huang, Jing, et al.
(författare)
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Gas exchange in fruits related to skin condition and fruit ripening studied with diode laser spectroscopy
- 2016
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Ingår i: Journal of Biomedical Optics. - 1083-3668. ; 21:12
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Tidskriftsartikel (refereegranskat)abstract
- The concentration of the biologically active molecular oxygen gas is of crucial importance for fruits in the metabolic respiration, maturation, and ripening processes. In our study, oxygen content and oxygen transport in fruits, exemplified by apples and guavas, were studied noninvasively by gas in scattering media absorption spectroscopy. The technique is based on the fact that free gases typically have 10,000 times narrower absorption features than the bulk material. The technique was demonstrated in studies of the influence of the fruit skin in regulating the internal oxygen balance, by observing the signal response of the internal oxygen gas to a transient change in the ambient gas concentration on peeled and unpeeled fruits. In addition, the gas exchange rate at different ripening stages was also studied in intact guavas.
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| 6. |
- Li, Tianqi, et al.
(författare)
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Application of Tunable Diode Laser Spectroscopy for the Assessment of Food Quality
- 2017
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Ingår i: Applied Spectroscopy. - : SAGE Publications. - 0003-7028 .- 1943-3530. ; 71:5, s. 929-938
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Tidskriftsartikel (refereegranskat)abstract
- Adequate food packaging is important to ensure food quality and prolong the shelf life of food. Frequently, the method of modified atmosphere packaging (MAP) is used. We used a tunable diode laser spectroscopy technique to detect the oxygen content in food packages, e.g., in packaged milk and bread. Different detection geometries were adopted to be able to collect scattering light that had passed through the gas volume in the packages, and to avoid the disturbance of ambient air. Furthermore, studies of the bread-baking process have been performed by measuring the water vapor signals in a fermenting dough. The results demonstrate that the technique has a great potential for nonintrusive assessment of food quality and the bread-baking process.
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| 7. |
- Lin, Huiying, et al.
(författare)
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Diagnostics of femoral head status in humans using high-resolution laser spectroscopy : In vitro studies
- 2017
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Ingår i: CLEO: Applications and Technology, CLEO_AT 2017. - 9781943580279 ; Part F43-CLEO_AT 2017
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Konferensbidrag (refereegranskat)abstract
- Osteonecrosis of the femoral head is caused by inadequate blood supply to the affected bone. The bone decay process due to lacking blood supply would be likely to be accompanied by the formation of gas-filled pores. We have introduced diode laser absorption spectroscopy to successfully detect water vapor signals from pores in the femoral heads retrieved from hip replacement operations in 19 patients. The Gas in Scattering Media Absorption Spectroscopy (GASMAS) variety of tunable laser spectroscopy was employed. The results open up for the possibility of improved diagnostics for a very common disease.
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| 8. |
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| 9. |
- Svanberg, Katarina, et al.
(författare)
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Laser spectroscopy to meet some challenges in medicine
- 2017
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Ingår i: International Conference on Photonics and Imaging in Biology and Medicine, PIBM 2017. - 9781557528209 ; Part F70-PIBM 2017
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Konferensbidrag (refereegranskat)abstract
- Laser based spectroscopic techniques can be used in the detection and therapy of many human diseases. Examples will be given from a variety of clinical areas, such as oncology, orthopedics and pediatrics, and also from the field of food safety and antibiotic control.
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| 10. |
- Svanberg, Sune, et al.
(författare)
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Laser spectroscopy applied to environmental, ecological, agricultural and food safety research
- 2017
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Ingår i: International Conference on Photonics and Imaging in Biology and Medicine, PIBM 2017. - 9781557528209 ; Part F70-PIBM 2017
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Konferensbidrag (refereegranskat)abstract
- Laser spectroscopy has a multitude of applications of importance to human and ecosystem well-being, such as in the environmental, ecological, agricultural and food safety areas. Recent work, mostly from SCNU, will be reviewed.
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