| 41. |
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| 42. |
- Jacobsson, Amanda, et al.
(författare)
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”Ambulanssjukvården behöver genomgripande förändringar”
- 2021
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Ingår i: Dagens Medicin. - : Dagens Medicin. - 1402-1943. ; :2021-06-23
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Debattörer från Ambulance health research network vill se en nationell ledningsstruktur, ökad evidens för vården, akademisk kompetens i ledningsfunktioner samt en nationell utbildnings- och kompetensstandard.
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| 43. |
- Johansson, Michael, et al.
(författare)
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Biogaspotential från urbana gräsytor – Förstudie med Helsingborgs stad som case
- 2020. - 2020:10
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Rapporten är en förstudie avseende potential för biogasproduktion i Helsingborg,baserad på vegetation från urbana gräsytor. Rapporten fokuserar på frågor rörande tekniska aspekter på hela kedjan, dvs. från skörd av stadsgräs till leverans av vegetationen till en biogasanläggning. Rapporten innefattar även stad-landperspektivet, och värdet av biogödseln, samt olika nyttor för urbana gräsytor genom bland annat ökad biologisk mångfald, etc.Bakgrunden till förstudien är bland annat Helsingborgs Stads miljöstrategiskaarbete med kommunala strategi- och policydokument, och där bland annatöversiktsplaner enligt Plan- och bygglagen (PBL) bör sträva efter att uppnå hållbarutveckling. I förstudien diskuteras bland annat: Teknik och logistik - skörd och leverans av stadsgräs tillbiogasanläggningar för minsta möjliga miljöpåverkan vid insamling,eventuell mellanlagring och transport Biogödselns relevans för lokal växtnäringsförsörjning, markförbättring ochkolinlagring Ekosystemtjänster vid nyttjande av stadsgräs från urbana områden Olika biogasanläggningars krav för mottagning av stadsgräs, i våtrespektivei torrrötningsanläggningar Möjligheter att i torrötningsanläggningar röta stadsgräs med rejekt frånkällsorterat matavfall Stadens klimat- och miljömål samt efterfrågan på biogas.Eftersom förstudien är av tvärvetenskaplig karaktär har olika metoder använts förinsamling av det empiriska materialet. Metoder som tillämpats i förstudien är blandannat studiebesök och intervjuer, samt genomförande av en workshop medämnesrelevanta aktörer. Helsingborg har under projekttiden agerat som lokalfallstudie. Studien visar sammanfattningsvis på: Potential – Helsingborgs stads långgräs från 370 hektar grönytor kan förse250 gasbilar med drivmedel motsvarande årlig körsträcka på ca 1500 mil.Studien visar på att med fler källor av urban grön biomassa skullepotentialen kunna tredubblas, t.ex. från våtmarksslåtter, golfbanor medmera. Vi kan utifrån dessa förutsättningar driva 5-7 gånger fler gasbilar ihela Skåne, dvs. ca 1500 bilar Förutsättningar – Samverkan och kunskapshöjande åtgärder är viktigt föratt skapa lokalt baserade cirkulära resursflöden. Klimat- och miljömålengör att Sverige behöver satsa betydligt mer på lokalt producerad biogas.För att komma vidare i denna strävan är det viktigt att utgå frånbiogasanläggningarnas mottagningskrav. Den kanske största utmaningensom påträffades i studien var att systemet anpassades från merkravspecifika förutsättningar ställda från just biogasanläggningarna Värde och nytta – Förutom att grön biomassa baserat på långgräs frånurbana grönytor ger biogasdrivmedel och biogödsel så skapas många andraekosystemtjänstbaserade nyttor för en lokal hållbar samhällsplanering.Sammanfattning
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| 44. |
- Kissopoulou, Antheia, et al.
(författare)
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Monozygotic twins with myocarditis and a novel likely pathogenic desmoplakin gene variant
- 2020
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Ingår i: ESC Heart Failure. - : Wiley. - 2055-5822. ; 7:3, s. 1210-1216
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Tidskriftsartikel (refereegranskat)abstract
- Myocarditis most often affects otherwise healthy athletes and is one of the leading causes of sudden death in children and young adults. Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically determined heart muscle disorder with increased risk for paroxysmal ventricular arrhythmias and sudden cardiac death. The clinical picture of myocarditis and ARVC may overlap during the early stages of cardiomyopathy, which may lead to misdiagnosis. In the literature, we found several cases that presented with episodes of myocarditis and ended up with a diagnosis of arrhythmogenic cardiomyopathy, mostly of the left predominant type. The aim of this case presentation is to shed light upon a possible link between myocarditis, a desmoplakin (DSP) gene variant, and ARVC by describing a case of male monozygotic twins who presented with symptoms and signs of myocarditis at 17 and 18 years of age, respectively. One of them also had a recurrent episode of myocarditis. The twins and their family were extensively examined including electrocardiograms (ECG), biochemistry, multimodal cardiac imaging, myocardial biopsy, genetic analysis, repeated cardiac magnetic resonance (CMR) and echocardiography over time. Both twins presented with chest pain, ECG with slight ST-T elevation, and increased troponin T levels. CMR demonstrated an affected left ventricle with comprehensive inflammatory, subepicardial changes consistent with myocarditis. The right ventricle did not appear to have any abnormalities. Genotype analysis revealed a nonsense heterozygous variant in the desmoplakin (DSP) gene [NM_004415.2:c.2521_2522del (p.Gln841Aspfs*9)] that is considered likely pathogenic and presumably ARVC related. There was no previous family history of heart disease. There might be a common pathophysiology of ARVC, associated with desmosomal dysfunction, and myocarditis. In our case, both twins have an affected left ventricle without any right ventricular involvement, and they are carriers of a novel DSP variant that is likely associated with ARVC. The extensive inflammation of the LV that was apparent in the CMR may or may not be the primary event of ARVC. Nevertheless, our data suggest that irrespective of a possible link here to ARVC, genetic testing for arrhythmogenic cardiomyopathy might be advisable for patients with recurrent myocarditis associated with a family history of myocarditis.
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| 45. |
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| 46. |
- Kothari, Simple Futarmal, et al.
(författare)
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Effect of repetitive transcranial magnetic stimulation on altered perception of One's own face
- 2020
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Ingår i: Brain Stimulation. - : Elsevier. - 1935-861X .- 1876-4754. ; 13:3, s. 554-561
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Chronic orofacial pain (COP) patients often perceive the painful face area as "swollen" without clinical signs; such self-reported illusions of the face are termed perceptual distortion (PD). The pathophysiological mechanisms underlying PD remain elusive.OBJECTIVE: To test the neuromodulatory effect of repetitive transcranial magnetic stimulation (rTMS) on PD in healthy individuals, to gain insight into the cortical mechanisms underlying PD.METHODS: PD was induced experimentally by injections of local anesthetic (LA) around the infraorbital nerve and measured as perceived size changes of the affected area. Participants were randomly allocated to inhibitory rTMS (n = 26) or sham rTMS (n = 26) group. The participants rated PD at baseline, 6 min after LA, immediately, 20 and 40 min after rTMS. The rTMS (inhibitory and sham) was applied to face (lip) representation area of primary somatosensory cortex (SI) as an intervention at 10 min after the LA, when the magnitude of PD is large. As inhibitory rTMS, continuous theta-burst stimulation paradigm (50 Hz) for 40s was employed to inhibit cortical activity.RESULTS: We demonstrated a significant decrease in the magnitude of PD immediately and 20 min after the application of inhibitory rTMS compared with sham rTMS (P < 0.006). In two control experiments, we also showed that peripheral muscle stimulation and stimulation of a cortical region other than the lip representation area had no effect on the magnitude of the PD.CONCLUSIONS: Inhibitory rTMS applied to a somatotopical-relevant cortical region modulates PD of the face in healthy individuals and could potentially have therapeutic implications for COP patients.
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| 47. |
- Krishnaraja, Abinaya, et al.
(författare)
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Vertical InAs/InGaAsSb/GaSb Nanowire Tunnel FETs on Si with Drain Field-Plate and EOT = 1 nm Achieving Smin= 32 mV/dec and gm/ID= 100 V-1
- 2020
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Ingår i: 2020 IEEE Silicon Nanoelectronics Workshop, SNW 2020. - 9781728197357 ; , s. 17-18
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Konferensbidrag (refereegranskat)abstract
- We present vertical InAs/InGaAsSb/GaSb nanowire tunnel FETs (TFETs) on Si demonstrating subthreshold swing (S) of 32 mV/dec with ION = 4 µA/µm for IOFF = 1 nA/µm at VDS = 0.3V. The demonstrated drive currents is the highest reported for a TFET with S below 40 mV/dec resulting in a transconductance efficiency as high as 100 V-1. These results have been achieved by optimizing the source segment growth scheme and the device processing. The devices are compliant with low-power logic applications capable of operation at IOFF = 100 pA/µm.
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| 48. |
- Kylén, Erik, et al.
(författare)
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Development of an Animated Video for Pre- and Postoperative Learning for Osteoarthritis Patients
- 2020
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Ingår i: Education and New Developments 2020. - Lisboa, Portugal. - 9789895481521 ; , s. 428-432
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Osteoarthritis (OA) is a condition in the joint that is developing for a long time and hit first and mainlyarticular cartilage, and it is a long-term chronic disease characterized by deterioration. In the final stage itis affected all the tissues of the joints such as bones, ligaments, arthritis, joint fluid and muscles, whichresults in bones rubbing together and creating stiffness, pain, and impaired movement. This disease canaffect the joints in the knees, hands, feet, spine and shoulder. OA is the single most common cause ofdisability in older adults worldwide. Patients need to receive detailed information about the disability,learn about their disease, its treatment and how to follow recommendations both before and after thesurgery. As hospital stays are shortening the need of information is increasing, as the patients need toprepare themselves at home before the operation, as well as take care of their rehabilitation when they arecoming home, discharged from hospital. In this paper we present a case study about the development of aweb-based animated video that was developed to support the learning for patients with OA, using adesign science research approach. DSR is an iterative process that include three iterative research cycles.The relevance cycle provided the requirements for the application from the very beginning. The relevancecycle, the rigor cycle and the design cycle were conducted iteratively, and have generated designalternatives that have been evaluated in discussions with OA surgery physicians, as representatives fromthe application domain.
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| 49. |
- Lagedal, Rickard, et al.
(författare)
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Coronary angiographic findings after cardiac arrest in relation to ECG and comorbidity
- 2020
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Ingår i: Resuscitation. - : Elsevier BV. - 0300-9572 .- 1873-1570. ; 146, s. 213-219
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: The relations between specific ECG patterns and coronary angiographic findings in cardiac arrest patients with different comorbidities are not properly assessed. More evidence is needed to identify patients with the highest risk for acute coronary artery disease as a cause of the cardiac arrest. This study aims to describe the coronary artery findings after cardiac arrest in relation to ECG and comorbidity.Method: A retrospective study of out-of-hospital cardiac arrest patients, with coronary angiography performed within 28 days. ECG on admission, comorbidity, PCI attempts and angiographic findings are described. Data were retrieved from national registries in Sweden.Results: Among 1133 patients with available ECG and angiography information the mean age was 64 years. The rate of shockable rhythm was 79 degrees 0. The total incidence of any significant stenosis in cardiac arrest patients without ST-elevation who underwent coronary angiography within 28 days was 71 degrees 0. The incidence of any stenosis in patients with normal ECG was 62.1 degrees 0 and in patients with LBBB, 59.3 degrees 0. In patients with ST-depression or RBBB, PCI attempts were made in 47.1 degrees 0 and 42.4 degrees 0 respectively, compared with 33.3 degrees 0 in patients with normal ECG. Among patients without ST-elevation, those with diabetes mellitus and those with initial shockable rhythm respectively, 84.8 degrees 0 and 71.5 had at least one significant stenosis.Conclusion: Our study suggests, that evaluation of ECG patterns and comorbidities in out-of-hospital cardiac arrest patients without ST-segment elevation may be important to identify those with a high risk of coronary artery lesions that could benefit from early revascularization.
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| 50. |
- Li, Man-Bo, et al.
(författare)
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Silver-Triggered Activity of a Heterogeneous Palladium Catalyst in Oxidative Carbonylation Reactions
- 2020
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Ingår i: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 59:26, s. 10391-10395
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Tidskriftsartikel (refereegranskat)abstract
- A silver-triggered heterogeneous Pd-catalyzed oxidative carbonylation has been developed. This heterogeneous process exhibits high efficiency and good recyclability, and was utilized for the one-pot construction of polycyclic compounds with multiple chiral centers. AgOTf was used to remove chloride ions in the heterogeneous catalyst Pd-AmP-CNC, thereby generating highly active Pd-II, which results in high efficiency of the heterogeneous catalytic system.
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