SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Wang Qiang) srt2:(2005-2009)"

Sökning: WFRF:(Wang Qiang) > (2005-2009)

  • Resultat 1-10 av 23
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Wang, Chunjiang, et al. (författare)
  • Phase alignment and crystal orientation of Al3Ni in Al-Ni alloy by imposition of a uniform high magnetic field
  • 2008
  • Ingår i: Journal of Crystal Growth. - : Elsevier BV. - 0022-0248 .- 1873-5002. ; 310:6, s. 1256-1263
  • Tidskriftsartikel (refereegranskat)abstract
    • Solidification experiments of aluminum-nickel binary alloys under uniform high magnetic fields have been conducted. The effects of high magnetic fields on the crystal orientation of Al3Ni were investigated by XRD and the alignment of primary phases Al3Ni were also analyzed. Experimental results showed that the easy magnetization axis of Al3Ni crystal oriented parallel to the imposed magnetic fields and the primary phase Al3Ni aligned perpendicular to the magnetic fields. Magnetic orientation of crystal was determined by magnetic anisotropy energy. Whereas the phase alignment should be contributed to the combined effects of magnetic orientation, crystal growth and the effects of magnetic fields on mass transport during solidification.
  •  
2.
  •  
3.
  • Liu, Hai-Bin, et al. (författare)
  • Synthesis of 3-aryl-5-t-butylsalicylaldehydes and their chiral Schiff base compounds
  • 2007
  • Ingår i: Synthetic Communications. - : Informa UK Limited. - 0039-7911 .- 1532-2432. ; 37:19-21, s. 3815-3826
  • Tidskriftsartikel (refereegranskat)abstract
    • Six meta-substituted salicylaldehyde compounds have been prepared in 68-90% yields by the Suzuki-Miyaura coupling reaction using 3-bromo-5-t-butylsalicylaldehyde (la) and arylboronic acids (2a-f) as reactants. Among the obtained products, 3-(4-fluorophenyl)-5-t-butylsalicylaldehyde (3b), 3-(4-methylphenyl)-5-t-butylsalicylaldehyde (3d), 3-(1-naphthyl)-5-t-butylsalicylaldehyde (3e), and 3-(2-naphthyl)-5-t-butylsalicylaldehyde (3f) have not been reported so far. A series of new Schiff base ligands (L1-L10) were obtained in 51-89% yields from these salicylaldehyde derivatives.
  •  
4.
  • Lou, Changsheng, et al. (författare)
  • Migration and rotation of TiAl3 particles in an Al-melt solidified under high magnetic field conditions
  • 2009
  • Ingår i: Journal of Alloys and Compounds. - : Elsevier BV. - 0925-8388 .- 1873-4669. ; 472:1-2, s. 225-229
  • Tidskriftsartikel (refereegranskat)abstract
    • The effects of high magnetic fields on the migration and rotation of TiAl3 particles in an Al-7 wt.% Si alloy were studied. Without magnetic fields, the rod-like TiAl3 particles segregate at the lower part of the solidified structure. Under high uniform magnetic fields, these particles rotate to an orientation with their longitudinal axes parallel to the direction of the magnetic flux. The segregation of the particles reduces with the increase of the magnetic flux density. A negative gradient field enhances the effect of the uniform magnetic field. By altering high magnetic fields, Al-Si alloy samples containing homogeneously distributed and preferably aligned TiAl3 particles were prepared.
  •  
5.
  • Wang, Jing, et al. (författare)
  • Pulse delay and advancement in ring resonator with mutual modes coupling
  • 2008
  • Ingår i: Proc SPIE Int Soc Opt Eng. - : SPIE.
  • Konferensbidrag (refereegranskat)abstract
    • We show that a ring resonator with mutual modes coupling can achieve pulse delay or advancement of tens nano-seconds, which is similar as a ring resonator with single mode. Nevertheless, the pulse response can be sensitively tunable either through mutual mode coupling or through waveguide-ring coupling in the vicinity of resonant frequency.
  •  
6.
  • Yu, Ling-Zhu, et al. (författare)
  • MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation.
  • 2007
  • Ingår i: Cell cycle (Georgetown, Tex.). - 1551-4005. ; 6:3, s. 330-8
  • Tidskriftsartikel (refereegranskat)abstract
    • It is well known that MAPK plays pivotal roles in oocyte maturation, but the function of MEK (MAPK kinase) remains unknown. We have studied the expression, subcellular localization and functional roles of MEK during meiotic maturation of mouse oocytes. Firstly, we found that MEK1/2 phoshorylation (p-MEK1/2, indicative of MEK activation) was low in GV (germinal vesicle) stage, increased 2h after GVBD (germinal vesicle breakdown), and reached the maximum at metaphase II. Secondly, we found that P-MEK1/2 was restricted in the GV prior to GVBD. In prometaphase I and metaphase I, P-MEK1/2 was mainly associated with the spindle, especially with the spindle poles. At anaphase I and telophase I, p-MEK1/2 became diffusely distributed in the region between the separating chromosomes, and then became associated with the midbody. The association of p-MEK1/2 with spindle poles was further confirmed by its colocalization with the centrosomal proteins, gamma-tubulin and NuMA. Thirdly, we have investigated the possible functional role of MEK1/2 activation by intravenous administration and intrabursal injection of a specific MEK inhibitor, U0126, and by microinjection of MEK siRNA into oocytes. All these manipulations cause disorganized spindle poles and spindle structure, misaligned chromosomes and larger than normal polar bodies. Our results suggest that MEK1/2 may function as a centrosomal protein and may have roles in microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte maturation.
  •  
7.
  •  
8.
  • Guo, Xiao-Hua, et al. (författare)
  • Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability of endothelial cells
  • 2006
  • Ingår i: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. - : Wiley. - 1600-0463 .- 0903-4641. ; 114:12, s. 874-883
  • Tidskriftsartikel (refereegranskat)abstract
    • This study aimed to determine the effects of advanced glycation end products (AGEs) on endothelial cytoskeleton morphology and permeability, and to detect the underlying signaling mechanisms involved in these responses. Cultured endothelial cells (ECs) were exposed to AGE-modified human serum albumin (AGE-HSA), and EC cytoskeletal changes were evaluated by observing fluorescence of F-actin following ligation with labeled antibodies. Endothelial permeability was detected by measuring the flux of TRITC-albumin across the EC monolayers. To explore the signaling pathways behind AGE-induced EC alteration, ECs were treated with either soluble anti-AGE receptor (RAGE) IgG, or the MAPK inhibitors PD98059 and SB203580 before AGE-HSA administration. To further elucidate possible involvement of the ERK and p38 pathways in AGE-induced EC changes, adenovirus-carried recombinant constitutive dominant-negative forms of upstream ERK and p38 kinases, namely MEK1(A) and MKK6b(A), were pre-infected into ECs 24 h prior to AGE-HSA exposure. AGE-HSA induced actin cytoskeleton rearrangement, as well as EC hyperpermeability, in a dose and time-dependent manner. The effects were attenuated in cells pretreated with anti-RAGE IgG, PD98059 or SB203580, respectively. EC pre-infection with MEK1(A) and MKK6b(A) also alleviated the effect of AGEs. Furthermore, adenovirus-mediated administration of activated forms of either MEK1 or MKK6b alone induced rearrangement of F-actin and hyperpermeability. The results indicate that ERK and p38 MAPK play important roles in the mediation of AGE-induced EC barrier dysfunction associated with morphological changes of the F-actin.
  •  
9.
  • Hu, Jinhong, et al. (författare)
  • Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults
  • 2008
  • Ingår i: PLOS ONE. - : PLOS. - 1932-6203. ; 3:4
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The P. falciparum chimeric protein 2.9 (PfCP-2.9) consisting of the sequences of MSP1-19 and AMA-1 (III) is a malaria vaccine candidate that was found to induce inhibitory antibodies in rabbits and monkeys. This was a phase I randomized, single-blind, placebo-controlled, dose-escalation study to evaluate the safety and immunogenicity of the PfCP-2.9 formulated with a novel adjuvant Montanide ISA720. Fifty-two subjects were randomly assigned to 4 dose groups of 10 participants, each receiving the test vaccine of 20, 50, 100, or 200 microg respectively, and 1 placebo group of 12 participants receiving the adjuvant only.METHODS AND FINDINGS: The vaccine formulation was shown to be safe and well-tolerated, and none of the participants withdrew. The total incidence of local adverse events (AEs) was 75%, distributed among 58% of the placebo group and 80% of those vaccinated. Among the vaccinated, 65% had events that were mild and 15% experienced moderate AEs. Almost all systemic adverse reactions observed in this study were graded as mild and required no therapy. The participants receiving the test vaccine developed detectable antibody responses which were boosted by the repeated vaccinations. Sixty percent of the vaccinated participants had high ELISA titers (>1:10,000) of antigen-specific antibodies which could also recognize native parasite proteins in an immunofluorescence assay (IFA).CONCLUSION: This study is the first clinical trial for this candidate and builds on previous investigations supporting PfCP-2.9/ISA720 as a promising blood-stage malaria vaccine. Results demonstrate safety, tolerability (particularly at the lower doses tested) and immunogenicity of the formulation. Further clinical development is ongoing to explore optimizing the dose and schedule of the formulation to decrease reactogenicity without compromising immunogenicity.TRIAL REGISTRATION: Chinese State Food and Drug Administration (SFDA) 2002SL0046; Controlled-Trials.com ISRCTN66850051 [66850051].
  •  
10.
  • Li, Dong-gang, et al. (författare)
  • Diffusion layer growth at Zn/Cu interface under uniform and gradient high magnetic fields
  • 2008
  • Ingår i: Materials Science & Engineering. - : Elsevier BV. - 0921-5093 .- 1873-4936. ; 495:1-2, s. 244-248
  • Tidskriftsartikel (refereegranskat)abstract
    • As a common phenomenon occurring in many material processes, diffusion may induce significant changes in composition and microstructure near the interface. In the present study, liquid/solid (Zn/Cu) interface diffusion experiments in high magnetic fields (up to 12 T) were conducted and the thickness changes of diffusion layer under different magnetic field conditions were examined. It was found that there were no noticeable effects of high magnetic fields on the formation of intermetallic phases at the interface. However, the magnetic flux density exerted a non-linear influence on the diffusion layer thickness. This phenomenon should be attributed to the effect of magnetic fields suppressing natural convection and inducing thermo-electromagnetic convection. In addition, the diffusion of Zn into Cu could be retarded by a magnetic field gradient. These results indicate that both the strength and the gradient of high magnetic fields can be used to control the diffusion behavior.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 23

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy