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Träfflista för sökning "WFRF:(Wiklund Gunnar) srt2:(1990-1999)"

Sökning: WFRF:(Wiklund Gunnar) > (1990-1999)

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  • Andersson, Thord, et al. (författare)
  • WITAS Project at Computer Vision Laboratory; A status report (Jan 1998)
  • 1998
  • Ingår i: Proceedings of the SSAB symposium on image analysis. ; , s. 113-116
  • Konferensbidrag (refereegranskat)abstract
    • WITAS will be engaged in goal-directed basic research in the area of intelligent autonomous vehicles and other autonomous systems. In this paper an overview of the project is given together with a presentation of our research interests in the project. The current status of our part in the project is also given.
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  • Säfström, Kåge, 1959-, et al. (författare)
  • Unstable coronary artery disease in post-menopausal women : Identifying patients with significant coronary artery disease by basic clinical parameters and exercise test
  • 1998
  • Ingår i: European Heart Journal. - : Oxford University Press (OUP). - 0195-668X .- 1522-9645. ; 19:6, s. 899-907
  • Tidskriftsartikel (refereegranskat)abstract
    • Background The diagnostic information from an ECG taken while at rest and an exercise test is considered less reliable in women than in men, mostly due to a high percentage offalse-positive tests. This can be explained by a lower pre-test likelihood of coronary heart disease.Aims To evaluate the diagnostic information that can be gained from basic clinical parameters, an ECG and exercise test in a group of post-menopausal women with symptoms of unstable coronary artery disease in order to identify patients with significant coronary artery stenoses.Methods and Results We prospectively studied 200 postmenopausal women admitted to the coronary care unit with symptoms of unstable coronary artery disease and ECG changes suggestive of ischaemia. The diagnostic value of common risk factors, myocardial enzymes and an early exercise test were assessed. A coronary angiogram was performed within 60 days. Median age was 67 years. On admission, 38% had ST depression on an ECG taken while at rest, 76% had T-wave inversion, and 41% increased enzyme levels. The coronary angiogram revealed that 15% had no atherosclerosis, 14% had atherosclerosis but no lesion ≥ 50% of luminal diameter and 71 % had at least one significant stenosis. Of patients with known indicators of atherosclerotic disease, all but one had atherosclerosis visualized on the coronary angiogram. A relative ST depression ≥ 0·1 m V and a low maximum workload at exercise test were strong predictors of significant coronary artery disease. The positive predictive value of ST depression was 91% and of low maximum workload 84%.Conclusion In post-menopausal women with signs of unstable angina and ischaemia on an ECG taken while at rest, the prevalence of coronary atherosclerosis is high, 85%. Contrary to earlier studies, ST T-changes at the early exercise test had a high positive predictive value, especially in combination with a low maximum workload with no false-positive results.
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