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- Adell, Gunnar, 1953-, et al.
(författare)
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p53 status : an indicator for the effect of preoperative radiotherapy of rectal cancer.
- 1999
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Ingår i: Radiotherapy and Oncology. - 0167-8140 .- 1879-0887. ; 51:2, s. 169-174
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Rectal carcinoma is a common malignancy, with a history of high local recurrence rates following surgery. In recent years. preoperative radiotherapy and refined surgical technique have improved local control rates.AIM: To investigate the relationship between expression of nuclear p53 protein and the outcome in rectal carcinoma, with and without short-term preoperative radiotherapy.MATERIAL: Specimens from 163 patients from the Southeast Swedish Health Care region included in the Swedish rectal cancer trial between 1987-1990.METHOD: New sections from the paraffin blocks of the preoperative biopsy and the surgical specimen were examined immunohistochemically using a p53 antibody (PAb 1801).RESULT: Expression of nuclear p53 protein was seen in 41% of the tumours. The p53 negative patients treated with preoperative radiotherapy had a significant reduction of local failure compared with the non-irradiated p53 negative patients (P = 0.0008). In contrast, p53 positive patients showed no benefit from preoperative radiotherapy. The interaction between p53 status and the benefit of radiotherapy was statistically significant (P = 0.018).CONCLUSION: Expression of nuclear p53 protein in rectal carcinoma seems to be a significant predictive factor for local treatment failure after preoperative radiotherapy. Further investigations are necessary to select patients for preoperative treatment based on analysis of the preoperative biopsies.
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| 2. |
- Andersson, Nils-Eric, et al.
(författare)
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The influence of hot rolling on the variation of through thickness structure of AA7010 thick plates
- 1997
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Ingår i: Thermo-Mechanical Processing in Theory, Modelling & Practice. - Stockholm : Svenska fören. för materialteknik. - 9163054213 ; , s. 284-289
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The variation of through thickness structure and yield strength of AA7010-T7451 thick plate has been investigated. Grain size at different depths were determined qualitatively by using optical microscopy. Texture measurements were carried out using x-ray technique at the same depths as grain size studies. Tensile property tests have been performed and the EBSP technique has been used to compare the degree of recovered and recrystallized grain structure at different depths. Tensile testing determined through thickness variations in yield. The expected W shape of longitudinal yield strength through thickness was not observed. The yield strength decreases towards the center of the plate. An increasing amount of big recrystallized grains (through the thickness from T/8 towards the center of the plate) appears to be the reason behind the decreasing through thickness yield strength.
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| 3. |
- Andersson, Nils-Eric, et al.
(författare)
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The influence of hot rolling on the variation of through thickness structure of AA7010 thick plates
- 1996
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Ingår i: Thermomechanical processing in theory, modelling and practice [TMP]2. - 9163054213 ; , s. 284-289
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The variation of through thickness structure and yield strength of AA7010-T7451 thick plate has been investigated. Grain sizes at different depths were determined qualitatively by using optical microscopy. Texture measurements were carried out using X-ray technique at the same depths as grain size studies and tensile property tests have been performed. EBSP techdque has been used to compare the degree of recovered and recrystallized grain structure at different depths. Tensile testing determined through thickness variations in yield strength. The well known W shape of longitudinal yield strength variation through the thickness was not observed. The influence of texture on the yield strength measured is discussed.
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| 8. |
- Blank, Vladimir D., et al.
(författare)
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Electric resistivity and magnetoresistance of some superhard and ultrahard fullerites in the range 300-2K
- 1999
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Ingår i: AIP Conference Proceedings vol. 486. - Melville, NY : American Institute of Physics (AIP). - 1563969009 ; , s. 416-420
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Konferensbidrag (refereegranskat)abstract
- Electric resistivity and magnetoresistance were measured on samples with disordered structure synthesized from pure C60 and C70 at pressures in the range 8 - 12.5 GPa and temperature 900 - 1500 K. Different type of behaviour were observed: semimetallic and semiconducting, depending on the particular short-range order of the structure.
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| 9. |
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| 10. |
- Essen, M, et al.
(författare)
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Some results on Q(p) spaces, 0
- 1997
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Ingår i: JOURNAL FUR DIE REINE UND ANGEWANDTE MATHEMATIK. - : WALTER DE GRUYTER & CO. ; 485, s. 173-195
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- For p is an element of (0, 1), let Q(p) be a proper subspace of BMOA defined by means of a modified Garcia norm. We give a boundary value criterion for a function to be in Q(p) and a necessary and sufficient condition in terms of p-Carleson measure for an
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