| 1. |
- af Klinteberg, Britt, et al.
(författare)
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Family psychosocial characteristics influencing criminal behaviour and mortality - possible mediating factors : a longitudinal study of male and female subjects in the Stockholm Birth Cohort
- 2011
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Ingår i: BMC Public Health. - : Springer Science and Business Media LLC. - 1471-2458. ; 11, s. 756-
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Tidskriftsartikel (refereegranskat)abstract
- Background: Family psychosocial characteristics in childhood have been associated with children's development into criminal behaviour and mortality. This study explored these possible relationships and examined alcohol and/or drug use and mental problems as possible mediating factors, highlighting gender-specific patterns. Methods: Data from Swedish subjects born in 1953 (n = 14,294) from the Stockholm Birth Cohort study were examined. Several indicators of adverse family factors and individual problems were included in the present study. The information was derived from various data sources, covering different periods. Gender-specific associations with incidence of criminality (1966-1980) and mortality (1981-2009) were analysed using logistic regression. Furthermore, the population attributable fraction (PAF) was calculated for all variables in the fully adjusted models which were positively related to the outcome. Results: Overall incidence of criminality and mortality was (m/f 32.3/6.6) and (m/f 6.1/3.5), respectively. The results showed that all aspects of family psychosocial and individual problems studied were associated with criminality for both genders. Among males, individual problems seemed to partly mediate these relations, but the associations remained statistically significant. Interestingly, the PAF analysis revealed a reduction in criminality of 17.5% when individual problems with alcohol and/or drug use were considered. Among females, a significant impact of alcohol and/or drug use on the association between family psychosocial characteristics and subsequent criminality was obtained. Inclusion of father's occupational class only somewhat reduced the estimates for the genders. Concerning male mortality, father's alcohol abuse was significantly related to an increased risk. When individual criminality was accounted for, the association was substantially reduced but remained statistically significant. Among females, when adjusting for family psychosocial factors, only the association between parents' mental problems and females' mortality was significant. None of the individual problem variables managed to explain this association. Conclusions: Family psychosocial characteristics were associated with both subsequent criminal behaviour and mortality. These connections were partly explained by individual risk factors, especially by alcohol and/or drug use. The practical implications of the findings point to the importance of addressing the individual's alcohol and/or drug use in reducing criminal behaviour, which would also lower the mortality rates.
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| 4. |
- Ahrén, Jennie C., et al.
(författare)
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Psychosocial determinants and family background in anorexia nervosa : Results from the Stockholm Birth Cohort Study
- 2012
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Ingår i: International Journal of Eating Disorders. - : John Wiley & Sons. - 0276-3478 .- 1098-108X. ; 45:3, s. 362-369
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to examine the associations between psychosocial factors and family background and incidence of anorexia nervosa (AN) in a Swedish cohort. Method: The Stockholm Birth Cohort, SBC (N = 14,294) contains information on social background and general health in males and females, born in Stockholm 1953. Hospitalizations for AN, based on diagnoses from the ICD-8 through ICD-10, were recorded from 1969 to 2002. Cox proportional hazard regression was used to measure the association between psychosocial characteristics and family background and the risk of AN. Results: Higher maternal education was associated with a higher risk for hospitalization for AN. An increased risk for AN was also found among females who stated that they “often compare their future prospects with others.” Discussion: Although the study is based on a low number of cases, it confirms earlier findings of higher maternal education among individuals with eating disorders in similar cohorts.
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| 5. |
- Ahrén-Moonga, Jennie, et al.
(författare)
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Levels of tumour necrosis factor-alpha and interleukin-6 in severely ill patients with eating disorders
- 2011
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Ingår i: Neuropsychobiology. - : S. Karger AG. - 0302-282X .- 1423-0224. ; 63:1, s. 8-14
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Tidskriftsartikel (refereegranskat)abstract
- Background: The underlying pathophysiology of eating disorders (ED) is dependent on complex interactions between psychological, biological and social factors. The purpose of the present study was to examine a possible increase in cytokines indicating inflammation, as measured by tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in ED patients, and to explore possible relationships between cytokines and self-reported personality traits. Methods: Female patients with severe ED (n = 26) were recruited consecutively from an inpatient clinic and were compared to age-matched healthy females (n = 12). Commercial ELISA tests developed for the measurement of serum levels of TNF-α and IL-6 were employed. Personality traits were measured using Karolinska Scales of Personality. Results: The patient group displayed increased levels of the cytokine TNF-α and a tendency towards increased IL-6 levels. Spearman's rank correlation coefficient was used to examine possible relationships between levels of cytokines and personality traits. The results showed that IL-6 levels were positively related to both somatic and psychic anxiety and to aggression scales, such as irritability and suspicion. Increased levels of TNF-α, in turn, were significantly correlated with high scores on the depression-related anxiety scale Inhibition of Aggression. However, increased levels of cytokines in the ED group did not seem to be mainly associated with symptoms of depression. Conclusion: We cannot rule out the possibility that comorbid conditions in the group contribute to the higher cytokine values. Further studies need to explore the possible influence of cytokines on the severity of ED and whether this might be mediated or moderated by specific personality traits.
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| 6. |
- Birath, Christina Scheffel, et al.
(författare)
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Moods and expectancies of female alcohol drinking - an exploratory study
- 2010
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Ingår i: Scandinavian Journal of Caring Sciences. - : Wiley. - 0283-9318 .- 1471-6712. ; 24:3, s. 472-481
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Tidskriftsartikel (refereegranskat)abstract
- Gaining access to information concerning mood states and expectations of change preceding a typical drinking occasion is important for understanding the trigger factors for drinking, and for alcohol abuse treatment planning. The objective of the present study was twofold: (i) to explore self-reported states of mood and expectancies preceding a typical drinking occasion vs. relations with parents and drinking outcome; and (ii) to investigate if vulnerability factors in terms of personality and health are related to severity of alcohol problems. The population consisted of 50 women attending a Swedish alcohol clinic. Semi-structured interviews were conducted. A mixed-methods design was used encompassing qualitative interview-data and quantitative data from questionnaires and medical journals. Nine out of ten patients had a diagnosis of alcohol dependence, and four out of five had parents with dependency problems. As compared to a female norm group, the patients displayed significantly higher anxiety-related traits and irritability. Moods were described by patients as mostly negative and expectancies of change were evenly distributed between reducing, enhancing or flight from feeling. An expectancy of flight when drinking was also related to a positive relation to mother. The findings pointed to the need for differentiating between coping with and expectancies of drinking. Further, a hierarchical cluster analysis resulted in two groups, indicating one group characterized by higher risk values on personality scales and more severe consequences of drinking. The contribution of a treatment design informed through a gender and culture perspective to treatment outcome was discussed.
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| 7. |
- Birath, Christina Scheffel, et al.
(författare)
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Women with Substance Abuse Problems Exposed to Men's Violence - A Public Mental Health Challenge
- 2013
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Ingår i: Journal of Addiction Research & Therapy. - : OMICS Publishing Group. - 2155-6105. ; 4:2, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To explore self-rated physical and psychological health in two groups of women with substance misuse problems, subjected to male violence.Methods: An examination of the health situation for women with substance dependence being exposed to male violence during life. The study took place in a Swedish context exploring data from 35 women with housing (WwH) and 44 homeless women (HW), regarding posttraumatic stress disorder symptoms, psychological and physical problems. Mann-Whitney U-test and Pearson’s correlation coefficient were used to calculate differences between groups and correlations.Results: The proportion of women being exposed to male violence during life for the studied group was 91% (72 of 79 women; WwH 29; HW 43). It was found that the WwH had physical health problems but compared to the HW, significantly less frequent. Regarding psychological health problems, both groups were suffering from self-reported problems, most notably in variables measuring stress susceptibility and embitterment, where both WwH and HW had scores markedly above norm mean scores. The HW had overall a poorer mental health profile as compared to the WwH. The WwH still maintained a foundation in the society compared to the HW regarding housing (100/0%), and custody over their children (91/0%).Conclusion: The study indicated that women with substance dependence and those who are victims of male violence have major problems with both their psychological and physical health. Particularly vulnerable are the HW. Past experiences of violence that have not been processed can further aggravate the women’s health. Thus, we suggest initiating the process of asking women if they have experienced violence in order to then be able to provide appropriate treatment interventions. For the WwH, this process may lead to a prevention of serious consequences for both their housing situation and for their health.
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| 8. |
- Birath Scheffel, Christina, et al.
(författare)
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Barn till våldsutsatta kvinnor med missbruksproblem
- 2014
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Syftet med föreliggande rapport är att utifrån insamlade och bearbetade data från ursprungsprojektet 'Studie om mäns våld mot kvinnor med missbruksproblem' sammanställa resultat som speglar barns psykosociala familjesituation där modern har missbruksproblem och i många fall blivit utsatt för manligt våld av partner och/eller släkting, bekant, eller myndighetsperson. Sammanfattningsvis lyfter resultaten, avseende barnens egen ogynnsamma utveckling och den generationsöverskridande problematiken i föreliggande studie, frågan om betydelsen av tidiga interventioner riktade till barn i riskmiljöer. Detta förefaller vara av särskild vikt för att ge underbyggt stöd för aktivt handlande avseende Barns rätt i samhället enligt Barnkonventionen.
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| 9. |
- Birath Scheffel, Christina, et al.
(författare)
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Risky drinking women : contrasting therapeutic approaches
- 2014
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Ingår i: Journal of Alcoholism & Drug Dependence. - : OMICS Publishing Group. - 2329-6488. ; 2:3, s. 1000160-
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Tidskriftsartikel (refereegranskat)abstract
- Background: The importance of early identification and effective treatment for risky drinking grows with the increasing rate of alcohol use by women. Objectives: This study aims to contrast treatment approaches for two samples of problem drinking women. Methods: The samples consisted of (i) 134 alcohol treatment-seeking Swedish women receiving long-term comprehensive services; and (ii) 152 US women who were not seeking treatment for alcohol but were medical outpatients with one of four conditions exacerbated by excessive alcohol use and received a brief intervention as part of a study. Data consisted of questionnaires assessing alcohol consumption, perceived stress and attitudes towards change. Results: While the treatment-seeking Swedish group drank more alcohol at the start of treatment, all women reduced their consumption of alcohol at the end of treatment/follow-up. Women who reported more stress drank more initially in both samples. Conclusion and Scientific Significance: This report contrasts two “extreme” approaches to treatment: longterm, open-ended, outpatient treatment and, time-limited, structured brief intervention for risky drinking women. Both treatment methods yielded positive results with significantly reduced drinking. Factors associated with successful outcome included the women’s attitudes toward treatment and conviction for the necessity of change in drinking habits.
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| 10. |
- DeYoung, Colin G., et al.
(författare)
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Variation in the catechol-O-methyltransferase Val(158)Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents
- 2010
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Ingår i: Psychiatric Genetics. - 0955-8829 .- 1473-5873. ; 20:1, s. 20-24
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Tidskriftsartikel (refereegranskat)abstract
- Objective Variation in the catechol-O-methyltransferase gene (COMT) has been associated with antisocial behavior in populations with attention deficit/hyperactivity disorder (ADHD). This study examined whether COMT would predict antisocial behavior in a sample with high levels of behavior problems, not necessarily ADHD. In addition, because previous research suggests that COMT may be associated with ADHD in males, association between COMT and ADHD symptoms was examined. Method This study tested whether variation in three polymorphisms of the COMT gene was predictive of symptoms of conduct disorder and ADHD, in a sample of 174 incarcerated Russian adolescent male delinquents. Results The Val allele of the Val(158)Met polymorphism was significantly associated with conduct disorder diagnosis and symptoms, whereas the Met allele was associated with ADHD symptoms. Conclusion The Val(158)Met polymorphism of the COMT gene shows a complex relation to behavior problems, influencing conduct disorder and ADHD symptoms in opposite directions in a high-risk population. Psychiatr Genet 20:20-24 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
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