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Träfflista för sökning "db:Swepub ;conttype:(scientificother);srt2:(1990-1999);srt2:(1996)"

Sökning: db:Swepub > Övrigt vetenskapligt/konstnärligt > (1990-1999) > (1996)

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Numrering	Referens	Omslagsbild	Hitta
1.	A Case of Stable Variation in Spoken Standard Estonian 1996 Proceedings (redaktörskap) (övrigt vetenskapligt/konstnärligt)
2.	A Comparison between Tove Janson´s Picture-Book "The Dangerous Journey" and Lewis Carroll´s "Alice in Wonderland" (Muumien taikaa : tutkimusretkiä Tove Janssonin maailmaan) 1996 Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract Referat:; (Svensk; litteraturvetenskaplig; bibliografi; )Består av föredragen från en konferens arrangerad i Tampere 1994 av Finska barnboksinstitutet samt ytterligare ett antal bidrag
3.	A place to live : gender research on housing in Africa 1996 Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract Be it a house or a makeshift, a shared or rented room, or a home of one's own, a place to live is central in surviving strategies of all urban households. In this volume the authors explore the gendered experiences of housing and housing rights in African countries. There are many differences but also many similarities in the pattern of women not having the same access and control over housing as men have. While women often are the bread-winners, they are also the home-makers, in the sense that it is women who put intense efforts in making a place home.
4.	Abdel-Motal, Ussama M (författare) Binding and immunogenicity of MHC class-I specific peptides and glycopeptides 1996 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract Short synthetic MHC class I (MHC-I) Db and Kb binding peptides were found to be strongly immunogenic and capable of inducing virus-specific cytotoxic T lymphocyte (CTL) responses. Restimulation of primed splenocytes with a low peptide concentration generated optimal CTL responses. CTL responses were found to correlate with the capacity of peptides to bind to MHC class I measured as MHC-I upregulation (I-II). Earlier studies using 15-16 mer peptides have demonstrated that CD4+ helperT-cells were required to induce optimal CTL responses. We investigated if optimal-length peptides still required CD4+ T-cell help to generate CTL. The results clearly established that activation of CTL responses by short optimal peptides did not require CD4+ T-cell help (III). MHC-I heavy chains can appear on the cell surface in different configurations, including forms which are designated as functionally "empty". Such empty MHC-I molecules can directly bind synthetic peptides having the correct motifs. A method to measure the fraction of "empty " Db molecules on different cells was established by using monoclonal antibodies, staining either for Db-bound glycopeptides and for Db itself (IV). This method has been used to measure "empty" MHC-I molecules on cells from TAP and b2-M gene targeted mice as well as TAP1/b2-M double mutant mice. The influence of pH on glycopeptide binding to MHC-I molecules was also investigated (V). MHC-I chains are known to internalize and recycle, to the cell surface, and this has been suggested to be important in peptide presentation. Whether MHC-I bound peptides also can recycle was not known. We have investigated this by two different approaches. First, glycopeptide recycling was tested with Gal2 specific monoclonal antibodies. By flow cytometry, a return of Gal2 epitopes to the surface was found, after cellular internalization and cell surface clearance by pronase treatment (VI). Recycling may be important for MHC-I processing of exogenous antigens. Second, this was tested using two different forms ofthe H-2Db molecule expressed in transgenic mice, either transmembraneous (Db-tm) or with a glycophosphatidylinositol (GPI)-lipid anchor (Db-GPI). Only the tm form of Db was found to readily internalize and recycle glycopeptides to the cell surface. When transgenic mice were immunized with influenza A virus and tested for CTL responses against an immunodominant nucleoprotein epitope, only Db-tm mice were found to generate specific CTL responses (VII). We have found that some Kb binding glycopeptides generated CTL which could recognize the carbohydrate present in a glycolipid form, in an MHC-I unrestricted way. An interesting finding in the present investigation was that glycopeptide and glycolipid specific CTL were found to use different T cell receptors (TCR:s) to recognize and kill target cells (VIII).
5.	AbdelHalim, SM, et al. (författare) The strong insulin release induced by forskolin in GK rats is accompanied by enhanced generation of cAMP in the diabetic islets 1996 Ingår i: DIABETOLOGIA. - 0012-186X. ; 39, s. 479-479 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
6.	AbdelRehim, M, et al. (författare) Enantiomer separation of underivatized tocainide and related compounds by CGC using ammonia as carrier gas 1996 Ingår i: JOURNAL OF MICROCOLUMN SEPARATIONS. - 1040-7685. ; 8, s. 151- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
7.	Abdsaleh, Shahin, et al. (författare) MR Imaging in Diagnosis of Primary Lymphedema. 1996 Ingår i: 1996 Scientific Program RSNA. ; , s. 419- Recension (övrigt vetenskapligt/konstnärligt)
8.	Abdulwahab, Fethi, 1964, et al. (författare) Quality assured plate solution 1996 Rapport (övrigt vetenskapligt/konstnärligt)
9.	Abedi, Mohammad Reza (författare) The chimeric SCID mouse in studies of the human immune system 1996 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract Several methods have been developed to transfer components of the human immune system into mice. In particular, the adoptive transfer of human Iymphoid cells or tissues into mice with severe combined immunodeficiency (SCID mice) has demonstrated the general applicability of such an approach. SCID mice have an autosomal recessive defect that impairs the rearrangement of antigen receptor genes in Iymphoid progenitors. Lack of an effective immune response, coupled with the intact hematopoietic microenvironment, allows the SCID mice to be reconstituted with human cells. Intraperitoneal transfer of human peripheral blood Iymphocytes was utilized to reconstitute the animals. Homing of human cells into mouse tissues and the synthesis of human immunoglobulins in chimenc SCID mice were analyzed. The effect of pretreatment regimens such as total body irradiation as well as the inf1uence of the source of cells on human immunoglobulin synthesis were investigated. Studies were performed to characterize animals repopulated with cells from individuals with primary immunoglobulin deficiencies and autoimmunity. The effect of gammaglobulin treatment on autoantibody production was investigated in SCID mice engrafted with cells from patients with primary biliary cirrhosis. Human antimitochondrial antibodies could be detected in reconstituted animals. Treatment with human gammaglobulin resulted in a rapid decrease of autoantibodies in the circulation. SCID mice engrafted with Iymphocytes from donors seropositive for Epstein-Barr virus frequently develop Iymphoproliferative disease of human origin. The antitumor effect of various treatment modalities such as antiviral or gammaglobulin treatments was studied in the chimeric SCID mice. A preventive effect of gammaglobulin treatment on tumor formation was found which was shown to be due to the presence of antibodies directed to Epstein-Barr virus-related antigens in the gammaglobulin preparations. The last study was aimed at developing a mouse model of suicide gene therapy for human plasma cell tumors. SCID mice were injected subcutaneously with human myeloma cell lines transduced with a herpes simplex thymidine kinase gene and subsequently treated with ganciclovir. An in vivo bystander effect was noticed when mice received mixtures of transduced and unmodified cells.
10.	Abeysekera, John, et al. (författare) Utveckling av metoder för provning och värdering av personlig skyddsutrustning med avseende på våt värmeavgivning 1996 Rapport (övrigt vetenskapligt/konstnärligt)

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