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Sökning: db:Swepub > Linköpings universitet > Högskolan i Skövde > Forskningsöversikt

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1.
  • Meng, N, et al. (författare)
  • RECK, a novel matrix metalloproteinase regulator
  • 2008
  • Ingår i: Histology and Histopathology. - : Hernandéz. - 0213-3911 .- 1699-5848. ; 23:8, s. 1003-1010
  • Forskningsöversikt (refereegranskat)abstract
    • Extracellular matrix (ECM) macromolecules are important for creating the cellular environments required during development and morphogenesis of tissues. Matrix metalloproteinases (MMPs) are a family of Zn-dependent endopeptidases that collectively are capable of cleaving virtually all ECM substrates, and play an important role in some physiological and pathological processes. MMP activity can be inhibited by some natural and artificial inhibitors. A newly found membrane-anchored regulator of MMPs, the reversion-inducing-cysteine-rich protein with kazal motifs (RECK), is downregulated when the cells undergo a process of malignant transformation, and is currently the subject of considerable research activity because of its specific structure and function. In this review, we have chosen to concentrate our efforts on the structure, function, regulation, and future prospect of RECK in order to provide a new target for prevention and treatment of tumours
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2.
  • Ziemke, Tom (författare)
  • The body of knowledge : On the role of the living body in grounding embodied cognition
  • 2016
  • Ingår i: Biosystems (Amsterdam. Print). - : Elsevier. - 0303-2647 .- 1872-8324. ; 148, s. 4-11
  • Forskningsöversikt (refereegranskat)abstract
    • Embodied cognition is a hot topic in both cognitive science and Al, despite the fact that there still is relatively little consensus regarding what exactly constitutes 'embodiment'. While most embodied Al and cognitive robotics research views the body as the physical/sensorimotor interface that allows to ground computational cognitive processes in sensorimotor interactions with the environment, more biologically based notions of embodied cognition emphasize the fundamental role that the living body - and more specifically its homeostatic/allostatic self-regulation - plays in grounding both sensorimotor interactions and embodied cognitive processes. Adopting the latter position - a multi-tiered affectively embodied view of cognition in living systems - it is further argued that modeling organisms as layered networks of bodily self-regulation mechanisms can make significant contributions to our scientific understanding of embodied cognition. 
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  • Resultat 1-2 av 2
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forskningsöversikt  (2)Ta bort avgränsningen
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refereegranskat (2)
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Li, Y. (1)
Sun, Xiao-Feng, 1959 ... (1)
Ziemke, Tom (1)
Zhang, Hong (1)
Meng, N (1)
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Linköpings universitet  (2)Ta bort avgränsningen
Högskolan i Skövde  (2)Ta bort avgränsningen
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