1.
Svensson, Leif, et al.
(författare)
Cirkulation, Bröstsmärtor
2009
Ingår i: Prehospital akutsjukvård. - : Stockholm: Liber. - 9789147084487 ; , s. 264-278
Bokkapitel (övrigt vetenskapligt/konstnärligt)
2.
Svensson, Leif, et al.
(författare)
Diabetes
2009
Ingår i: Prehospital akutsjukvård. - : Stockholm: Liber. - 9789147084487 ; , s. 316-325
Bokkapitel (övrigt vetenskapligt/konstnärligt)
3.
Bremer, Anders, 1957-, et al.
(författare)
Mötet med närstående
2009. - 1
Ingår i: Prehospital akutsjukvård. - : Liber. - 9789147084487 ; , s. 150-161
Bokkapitel (övrigt vetenskapligt/konstnärligt)
4.
Nyström, Maria, et al.
(författare)
Psykisk ohälsa
2009
Ingår i: Prehospital akutsjukvård. - : Liber. - 9789147084487 ; , s. 337-348, s. 703-739
Bokkapitel (övrigt vetenskapligt/konstnärligt)
5.
Sarlöv, Catharina, et al.
(författare)
Obstruktiv lungsjukdom
2009
Ingår i: Prehospital akutsjukvård. - Stockholm : Stockholm: Liber. - 9789147084487 ; , s. 243-251
Bokkapitel (övrigt vetenskapligt/konstnärligt)
6.
Borovszky, Helena, et al.
(författare)
Stroke
2009
Ingår i: Prehospital akutsjukvård. - : Stockholm: Liber. - 9789147084487 ; , s. 325-330
Bokkapitel (övrigt vetenskapligt/konstnärligt)
7.
8.
Dillenbeck, Emelie, et al.
(författare)
The design of the PRINCESS 2 trial: A randomized trial to study the impact of ultrafast hypothermia on complete neurologic recovery after out-of-hospital cardiac arrest with initial shockable
2024
Ingår i: American Heart Journal. - : MOSBY-ELSEVIER. - 0002-8703 .- 1097-6744. ; 271, s. 97-108
Tidskriftsartikel (refereegranskat) abstract
Background Delayed hypothermia, initiated after hospital arrival, several hours after cardiac arrest with 8-10 hours to reach the target temperature, is likely to have limited impact on overall survival. However, the effect of ultrafast hypothermia, i.e., delivered intra-arrest or immediately after return of spontaneous circulation (ROSC), on functional neurologic outcome after out -of -hospital cardiac arrest (OHCA) is unclear. In two prior trials, prehospital trans -nasal evaporative intra-arrest cooling was safe, feasible and reduced time to target temperature compared to delayed cooling. Both studies showed trends towards improved neurologic recovery in patients with shockable rhythms. The aim of the PRINCESS2-study is to assess whether cooling, initiated either intra-arrest or immediately after ROSC, followed by in -hospital hypothermia, significantly increases survival with complete neurologic recovery as compared to standard normothermia care, in OHCA patients with shockable rhythms. Methods/design In this investigator -initiated, randomized, controlled trial, the emergency medical services (EMS) will randomize patients at the scene of cardiac arrest to either trans -nasal cooling within 20 minutes from EMS arrival with subsequent hypothermia at 33 degrees C for 24 hours after hospital admission (intervention), or to standard of care with no prehospital or in -hospital cooling (control). Fever ( > 37,7 degrees C) will be avoided for the first 72 hours in both groups. All patients will receive post resuscitation care and withdrawal of life support procedures according to current guidelines. Primary outcome is survival with complete neurologic recovery at 90 days, defined as modified Rankin scale (mRS) 0-1. Key secondary outcomes include survival to hospital discharge, survival at 90 days and mRS 0-3 at 90 days. In total, 1022 patients are required to detect an absolute difference of 9% (from 45 to 54%) in survival with neurologic recovery (80% power and one-sided alpha= 0,025, beta = 0,2) and assuming 2,5% lost to follow-up. Recruitment starts in Q1 2024 and we expect maximum enrolment to be achieved during Q4 2024 at 20-25 European and US sites. Discussion This trial will assess the impact of ultrafast hypothermia applied on the scene of cardiac arrest, as compared to normothermia, on 90 -day survival with complete neurologic recover y in OHCA patients with initial shockable rhythm. Trial registration NCT06025123. (Am Heart J 2024;271:97-108.)
9.
Hagiwara, Magnus, et al.
(författare)
Vård och bedömning
2009
Ingår i: Prehospital akutsjukvård. - : Stockholm: Liber. - 9789147084487 ; , s. 117-145
Bokkapitel (övrigt vetenskapligt/konstnärligt)
10.
Henriksson, Catrin, et al.
(författare)
Knowledge and attitudes toward seeking medical care for AMI-symptoms
2011
Ingår i: International Journal of Cardiology. - : Elsevier BV. - 0167-5273 .- 1874-1754. ; 147:2, s. 224-227
Tidskriftsartikel (refereegranskat) abstract
Background: Time is crucial when an acute myocardial infarction (AMI) occurs, but patients often wait before seeking medical care. Aim: To investigate and compare patients' and relatives' knowledge of AMI, attitudes toward seeking medical care, and intended behaviour if AMI-symptoms occur. Methods: The present study was a descriptive, multicentre study. Participants were AMI-patients <= 75 years (n = 364) and relatives to AMI-patients (n = 319). Questionnaires were used to explore the participants' knowledge of AMI and attitudes toward seeking medical care. Results: Both patients and relatives appeared to act more appropriate to someone else's chest pain than to their own. Patients did not have better knowledge of AMI-symptoms than relatives. Women would more often contact someone else before seeking medical care. A greater percentage of elderly (65-75 years), compared to younger individuals, reported that they would call for an ambulance if chest pain occurred. Conclusions: There were only minor differences between patients and relatives, regarding both knowledge and attitudes. It seems easier to act correctly as a bystander than as a patient. Therefore, in order to decrease patients' delay time it is important to educate relatives as well as patients on how to respond to symptoms of an AMI.
