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- Belfrage, Per, et al.
(författare)
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Dispersion of viable pig liver cells with collagenase
- 1975
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Ingår i: Life Sciences. - : Elsevier BV. - 1879-0631 .- 0024-3205. ; 17:8, s. 1219-1225
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Tidskriftsartikel (refereegranskat)abstract
- Viable suspended hepatocytes were prepared from surgical biopsy specimens of pig and human liver by digestion with collagenase. Initial perfusion of the tissue through cannulated blood vessels with 0.5 mM EGTA followed by 0.2% collagenase gave the best results. 20−870 × 106 cells of which 60–95 % excluded trypan blue were obtained from 5–30 g pig liver pieces, while results with human liver specimens were usually less satisfactory. In some experiments, however, viable cells, as judged by vital stain exclusion and ability to synthesize lipids were obtained in sufficient yield. In the pig hepatocytes glycerolipid synthesis from [3H] glycerol and oxidation and esterification of [14C] oleic acid had the same characteristics as those observed earlier in rat hepatocytes.
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- Frisén, Lars, 1939, et al.
(författare)
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A simple relationship between the probability distribution of visual acuity and the density of retinal output channels.
- 1976
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Ingår i: Acta ophthalmologica. - 0001-639X. ; 54:4, s. 437-44
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Tidskriftsartikel (refereegranskat)abstract
- Throughout the retina, the parameters of the probability distribution of visual acuity for monochromatic interference fringes are closely proportional to the number of retinal ganglion cells per degree of visual angle. There are no simple relationships to receptor spatial frequencies. These findings suggest that neuro-retinal acuity is determined principally by the spatial frequency of neural output channels.
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- Frisén, Lars, 1939, et al.
(författare)
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Communicating exophthalmos: a sign of bilateral orbital roof defects.
- 1978
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Ingår i: Acta neurochirurgica. - 0001-6268. ; 41:1-3, s. 157-61
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Tidskriftsartikel (refereegranskat)abstract
- The term communicating exophthalmos is suggested for a condition where manual retropulsion of one eye results in proptosis of the other eye. This sign was observed in a patient with bilateral pulsating exophthalmos. The pulsating exophthalmos was ascribed to orbital roof defects in combination with post-traumatic hydrocephalus. It was controlled by a shunting procedure.
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- Frisén, Lars, 1939, et al.
(författare)
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Cyclic compression of the intracranial optic nerve: patterns of visual failure and recovery.
- 1976
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Ingår i: Journal of neurology, neurosurgery, and psychiatry. - 0022-3050. ; 39:11, s. 1109-13
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Tidskriftsartikel (refereegranskat)abstract
- A patient with a cystic craniopharyngioma below the right optic nerve had several recurrences requiring surgery. Finally the cyst was connected with a subcutaneous reservoir by means of a fine catheter. Symptoms of optic nerve compression recurred more than 50 times during the following year, and were relieved within seconds upon drainage of the reservoir. In each cycle, a drop in visual acuity preceded a measurable change in the visual field. The pattern of field changes was an increasingly severe, uniform depression. Optic nerve ischaemia induced by compression was probably the most important factor causing visual failure in this case.
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- Frisén, Lars, 1939, et al.
(författare)
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Detection of extracranial carotid stenosis by computed tomography.
- 1979
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Ingår i: Lancet (London, England). - 0140-6736. ; 1:8130, s. 1319-20
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Tidskriftsartikel (refereegranskat)abstract
- Ten patients with transient ischaemic attacks (T.I.A.) within the carotid territory were examined by aortic-arch angiography and computed tomography (C.T.) of the neck. C.T. showed evidence of carotid calcifications in all 17 angiographically abnormal arteries, and there was no evidence of calcification in the 3 normal arteries. C.T. of the neck promises to be a useful technique for the investigation of patients with T.I.A.s.
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