| 1. |
- Hedlin, Gunilla, et al.
(författare)
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Astma
- 1992
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Ingår i: Allergi och astma hos barn. - Lund : Draco Läkemedel AB. - 9186058320
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Bokkapitel (refereegranskat)
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| 2. |
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| 3. |
- Wennergren, Göran, 1947, et al.
(författare)
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Characteristics and prognosis of hospital-treated obstructive bronchitis in children aged less than two years.
- 1992
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Ingår i: Acta paediatrica (Oslo, Norway : 1992). - 0803-5253. ; 81:1, s. 40-5
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Tidskriftsartikel (refereegranskat)abstract
- In a prospective study 101 children aged less than 2 years (median age 10 months), were examined the first time they were admitted to a paediatric ward for asthmatic symptoms. Two-thirds were boys and 58 had parents or siblings with allergic symptoms. During winter-spring, respiratory syncytial (RS) virus was verified in 50% of children. Other viral agents were adenovirus, parainfluenza 3, coxsackie B 2, ECHO 6 and rotavirus. At the acute stage, 54% of the children displayed changes on pulmonary X-ray. The total IgE value was greater than or equal to +2 SD score units in 14 children. At reinvestigation after 3-4.5 years, when the children were aged 3.3-6.3 years, 53% were free from asthmatic symptoms; the median age for the last episode was 2 years. A total of 33% had mild asthma, 8% moderate and 6% severe asthma. The factors which correlated significantly with persistent asthma were: (1) The need for daily medication for at least 6 months. (2) A young age in conjunction with the first wheezing episode and on the first admission to a paediatric ward because of asthmatic symptoms. (3) Other past or present atopic symptoms. Heredity, tobacco smoking at home, having a furry pet, RS virus infection, or high total IgE at the time of the first admission did not correlate significantly with the persistence of asthma 3-4.5 years later. The results emphasize the good overall prognosis of wheezing in early childhood, even when the wheezing is severe enough to lead to inpatient treatment.
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| 4. |
- Holmgren, Daniel, 1945, et al.
(författare)
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Transcutaneous blood gas monitoring during salbutamol inhalations in young children with acute asthmatic symptoms.
- 1992
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Ingår i: Pediatric pulmonology. - 8755-6863. ; 14:2, s. 75-9
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Tidskriftsartikel (refereegranskat)abstract
- The effect of salbutamol inhalations on transcutaneous blood gases was investigated in 23 children (aged 11 months-2.5 years) with asthmatic symptoms. After one salbutamol inhalation there was a mean increase in transcutaneous PO2 (tcPO2) of 0.5 kPa (P less than 0.01); after a second dose given 30 minutes later, the mean increase was 1.2 kPa (P less than 0.001). The increase in tcPO2 after only one dose of salbutamol was significantly correlated to age (P less than 0.01). No such correlation was observed after a second dose. The overall increase in tcPO2 after two salbutamol inhalations showed a negative correlation to the duration of the current symptomatic period (P less than 0.05). We conclude that salbutamol inhalations have beneficial effects in young children with acute asthmatic symptoms, even below the age of 18 months, provided that an adequate dose reaches the lung and preferably at an early stage of obstruction.
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