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- Malmgren, Helge, 1945
(författare)
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Asteno-emotionellt syndrom, kognitiv dysfunktion : Astheno-emotional syndrome and cognitive dysfunction after whiplash injuries
- 1999
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Ingår i: Konferens och utbildningsdag om whiplash-skador, Göteborg 19/10 1999.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Typiska manifestationer av lindriga till måttliga asteno-emotionella syndrom (AE-syndrom, AED): • Koncentrationssvårigheter (ssk. svårighet att upprätthålla koncentration över tid) • Psykisk uttröttbarhet • Sekundära minnestörningar (påverkan såväl på korttidsminnet som på lagring till och framtagning från långtidsminnet) • Emotionell labilitet • Irritabilitet • Överkänslighet för sensoriska stimuli Tänkbara orsaker till AED vid whiplash-trauma: • Vid uppenbar hjärnskada kan ett tydligt AED framträda relativt tidigt. • Ett lindrigt AED baserat på en centralnervös funktionsrubbning kan möjligen uppstå primärt, även om amnesi för episoden inte föreligger. Observera att ett lindrigt AE-syndrom i denna fas kan maskeras av andra, mer påtagliga symtom. • Ett patologiskt signalflöde från den skadade nackregionen (vare sig det når medvetandet eller ej) kan sannolikt innebära en överbelastning av högre centra i CNS, och därför ge ett lindrigt sekundärt AED utan primär dysfunktion i CNS. • Kroniska, upplevda symtom av skadan (smärta, yrsel etc) kan på längre sikt också ge en sådan överbelastning , vilket leder till ett lindrigt AED. Tänkbara följder av AED vid whiplash: AED kan i sig ge psykogena komplikationer, svåra eller omöjliga att skilja från reaktioner av typ PTSD och från sekundära reaktioner på övriga kroniska symtom av skadan. Vanliga psykogena komplikationer: • Ängslan och ångest • Spänning • Huvudvärk • Vegetativa symptom • Depressivitet Av dessa reaktioner är den sekundära depressionen vid utdragna besvär särskilt viktig att beakta, liksom givetvis möjligheten till många onda cirklar med övrig symtomatologi vid whiplashskador (AED --> ökad smärtreaktivitet --> värre AED). Förslag till revision av vårdprogram: • Anamnes beträffande AED bör alltid tas tidigt i förloppet • Neuropsykologisk utredning kan vara indicerad tidigt, även om tydliga kognitiva symtom inte spontant rapporterats • Patientinformationen bör tidigt innefatta en diskussion av symptom, prognos och lämpliga åtgärder vid lindriga astenoemotionella syndrom • Försiktighet med återgång till fullt arbete innan AED har uteslutits.
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| 2. |
- Munthe, Christian, 1962
(författare)
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Ethical Aspects of Risk Decisions
- 1999
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Ingår i: Novakova (ed.), Amalgam and Health - New Perspectives on Risks. - Stockholm : Forskningsrådsnämnden. ; , s. 160-164
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Edgerton, Michael, et al.
(författare)
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Multiple Sound Sources of the Vocal Tract.
- 1999
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Ingår i: Status and Progress Report. ; , s. 131-140
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- This paper will discuss multiple sound sources of the vocal tract, focusing specifically on one type of multiple sound source, that of (imitated Tibetan) chant. First I will present a physiological outline of multiple sound sources, in order to better understand chant as just one of the many types of multiple sound sources that composers and performers might utilize. The main body of the paper will then describe a collaborative study between Drs. Khidr, Bless and the author, which is designed to quantify the physiologic and acoustic parameters of chant. By doing so, this paper will attempt to merge current musical compositional imperatives with current scientific rigor and rationale. Ultimately, this cross-disciplinary work will impact both voice science and musical expression as much more needs to be learned regarding the limits of the voice. Compositionally, the value for introducing scientific rigor into the world of new music has been well understood by those associated with electronic and computer music, acoustic modeling and design, or for composers exploring the limits of expression associated with the extensions of performance technique. However, the voice has been treated much with the same musical aesthetic and principles of phonation that existed during the 18th and 19th centuries. So that while instruments have incorporated multiphonics, complex (noise-based) frequency signals, and transient gestures, the voice has remained, for the most part, the carrier of simple melodic formuli. Therefore, this paper will suggest that by knowing the limits of the voice and what is pedagogically safe, contemporary performance/compositional practices will begin to explore and expand upon the current trends of positing simple solutions when approaching the voice.
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| 6. |
- Munthe, Christian, 1962
(författare)
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Genetic Treatment and Preselection. Ethical Similarities and Differences
- 1999
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Ingår i: Nordgren, A (ed.), Gene Therapy and Ethics, Studies in Bioethics and Research Ethics No. 4, Uppsala 1999: Acta Universitatis Upsaliensis. - Uppsala : Acta Universitatis Upsaliensis. - 915544640X ; , s. 159-173
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Medical genetic interventions can be performed in two ways. First, genetic defects may be repaired (gene therapy). Secondly, a possible future individual (an embryo or a possible combination of gametes) may be preselected because of its favourable genetic make-up (by using genetic diagnostic methods and procedures from reproductive medicine so called Preimplantation Genetic Diagnosis). The first kind of intervention means that someone gets medical treatment in the normal sense, however, the second kind does not. Rather, in that case, the potential patient is exchanged for another individual who is in no need of treatment. The paper explores to what extent arguments for and against these kinds of genetic intervention apply equally to all of them. For example, may the benefits that can be achieved through gene therapy be equally well achieved through genetic preselection? Are fears of a resurrection of eugenic practices through gene technology more warranted regarding therapeutic interventions than regarding preselective ones (or vice versa)? Since genetic preselection is an intervention at the germ-line level and is presently clinically applied: How is it possible to motivate that clinical application of germ-line gene therapy is not similarily permitted?
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| 7. |
- Munthe, Christian, 1962
(författare)
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Pure Selection. The Ethics of Preimplantation Genetic Diagnosis and Choosing Children without Abortion
- 1999
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Preimplantation ge¬netic diagnosis (PGD) is taken to mark the starting-point of a new phase in human reproduction, where the possibility of choosing children on genetic grounds without having to resort to ethi¬cally controversial procedures (such as abortion) will grad¬ually increase. Ethical and political issues actu¬alised by this develop¬ment are addressed. The discussion touches upon issues regarding the moral status of em¬bryos and gametes, the moral import of respecting individual auton¬omy and its implications for the requirement of informed consent in health-care, the connec¬tion between sickness, dis¬ability and the value of life, the moral status of possible future people, and the connection between choosing children and eugenic policies of the past. Practical policy issues are adressed on the basis of this, as well as an empirical case-study of the intro¬duction of PGD in Sweden. The book ends up in a set of recommendations regarding the management of re¬search on, introduction and routine use of procedures for pure se¬lection, both within health care and from the point of view of society as a whole. It is argued that research on such procedures should be allowed and supported by society. However, tight restrictions regarding the clinical introduction of new procedures in this area is highly desirable. A rough model for implementing such re¬strictions is also pre¬sented. It is further asserted that, although reasons of economy and safety should limit the access to pure se¬lection, society should not apply any explicit restrictions based on ideasregarding how different traits affect a person’s quality of life. It is stressed that, in order to to avoid a re¬sur¬rection of eugenic policies of the past, the development in this field un¬der¬lines the need for continued and strengthen public support to the sick, dis¬abled and mentally retarded.
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